Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Voclosporin shows clinical promise for treatment of active lupus nephritis

1. A significantly greater proportion of patients in the voclosporin group achieved complete renal responses after 52 weeks compared to the placebo group. 2. The...

Reports of myocarditis in healthy adolescents after Pfizer-BioNTech COVID-19 Vaccination

 1. In a case series, 7 healthy male adolescents aged 14-19 developed acute myocarditis or myopericarditis within 4 days of receiving the second dose of...

Effect of cognitive behavioral therapy-based counseling on perceived stress in pregnant women with history...

1. Cognitive behavioral therapy (CBT)-based counseling significantly improved perceived stress, anxiety, and quality of life among women with primary infertility. 2. Measures of depression suggested...

Pembrolizumab plus concurrent chemoradiation therapy associated with robust antitumor activity in patients with locally...

1. Concomitant pembrolizumab plus chemoradiation therapy was associated with improved antitumor activity and safety profile in patients with previously untreated, locally advanced, stage III...

Maternal influenza vaccine during pregnancy not linked to adverse early childhood outcomes

1. Over a mean follow-up period of 3.6 years, no significant association was detected between maternal influenza vaccination during pregnancy and early childhood health...

Continuous glucose monitoring results in better glycemic control compared to conventional methods in patients...

1. Among adults with poorly controlled type 2 diabetes treated with basal insulin without prandial insulin, continuous glucose monitoring resulted in significantly lower hemoglobin...

Shorter antibiotic therapy for prosthetic joint infection caused worse outcomes

1. A six-week antibiotic therapy was not shown to be non-inferior to a 12-week antibiotic therapy for patients with confirmed prosthetic joint infections. 2.The six-week...

Genetic variants associated with unexplained sudden cardiac death in adult white and African American...

1. Nearly 20% of participants with unexplained sudden cardiac death carried pathogenic or likely pathogenic variants of cardiomyopathies and arrhythmia syndromes. Evidence Rating Level: 2...

Study outlines trends in pediatric toxic ingestions during the COVID-19 pandemic

1. In this national study of poison control center reports, there was an absolute decrease in reported pediatric ingestions during the first year of...

Carriers of genetic variants of inherited cardiomyopathies and arrhythmias associated with unexplained sudden cardiac...

1. In this study of White and African American adults who had unexplained sudden cardiac death, nearly 20% of individuals had pathogenic or likely...

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