Direct oral anticoagulants increase bleeding risk after intracerebral hemorrhage in patients with atrial fibrillation
1. Ischemic stroke occurred less often in patients with atrial fibrillation on DOACs compared to those on placebo. 2. Patients...
Chronic Disease
Reports of high-impact chronic disease studies by medical professionals
Ivonescimab improves survival in advanced non-small cell lung cancer
1. Patients in the ivonescimab group demonstrated a significantly greater progression-free survival than those in the pembrolizumab group. 2. Grade...
Utilization of an early-life risk factor score to determine later life type 2 diabetes risk
Longitudinal association of cumulative risk factors in early life, genetic risk, and healthy lifestyles during adulthood with the risk of...
BRAFV600-mutant ctDNA as a Prognostic Biomarker in Resected Stage III Melanoma
1. ctDNA detection was found to have a relapse HR of 2.91 in the placebo and HR 2.98 in the...
Motivational interviewing not effective in reducing rehospitalisation and improving patient activation among patients with respiratory failure
1. Standalone motivational interviewing post-discharge did not reduce rehospitalization in older multimorbid patients with heart failure or chronic obstructive pulmonary...
Upper extremity pain associated with poor functional recovery post-stroke
1. A third of stroke survivors experienced upper extremity pain, which was associated with poor arm functional recovery at 12...
Exenatide does not slow Parkinson’s disease progression compared to placebo
1. There was no significant difference in functional outcome between both groups at 96 weeks. 2. Exenatide was safe and...
Ultrasound-guided radiofrequency ablation may be effective for treatment of aldosterone-producing adenomas
1. There were no gastric and adrenal puncture instances among patients who underwent radio-ablation in both groups. 2. Majority of...
Inflammatory bowel disease may be associated with increased risk of osteoporosis and osteopeia
1. In postmenopausal patients with ulcerative colitis (UC) or Crohn’s disease (CD), approximately one-third had osteoporosis while approximately 40% had...
Increased tirzepatide use for glycemic and weight control since United States market entry
1. In this retrospective cohort study, tirzepatide dispensations were found to have increased significantly following approval in the United States...