Effect of high elevation on deep vein thrombosis: a multicenter cohort study
1. Injuries suffered at high elevations are associated with a significantly higher odds of developing deep vein thrombosis (DVT) compared...
Chronic Disease
Reports of high-impact chronic disease studies by medical professionals
Duloxetine is effective in refractory chronic cough
1. Duloxetine is significantly more effective than placebo at reducing refractory chronic cough (RCC) frequency and sensitivity. Evidence Rating Level:...
Berberine is safe and effective in lowering lipoprotein cholesterol levels in metabolic dysfunction-associated steatotic liver disease
1. In diabetes-free individuals with metabolic dysfunction–associated steatotic liver disease (MASLD) and obesity, berberine is safe, well-tolerated, and associated with...
Ethosuximide may not be effective for the treatment of abdominal pain in irritable bowel syndrome
1. Ethosuximide was not superior to placebo for the treatment of abdominal pain in adults with irritable bowel syndrome. Evidence...
One in three people with cystic fibrosis may experience nephrolithiasis during their life
1. Nearly one in three people with cystic fibrosis experienced nephrolithiasis during their lifetime. 2. The degree of exocrine pancreatic...
Brain-penetrant enzyme replacement therapy improves biomarkers in mucopolysaccharidosis type II
1. In this open-label phase 1–2 study, pediatric patients with mucopolysaccharidosis type II treated with tividenofusp alfa showed substantial reductions...
Metformin is associated with lowering maternal hyperglycemia and reducing the risk of neonatal hypoglycemia among pregnant patients at risk of preterm delivery
1. Among pregnant patients at risk of preterm delivery, metformin was associated with lower mean maternal glucose values and a...
Aerobic-resistance training and high-intensity interval training may improve metabolic and functional outcomes in adults with type 2 diabetes
1. 12 weeks of aerobic–resistance training and high-intensity interval training improved metabolic, functional, and quality-of-life outcomes in adults with type...
An elevated Apolipoprotein B to Apolipoprotein A ratio may be associated with increased kidney stone recurrence
1. A higher ApoB/ApoA ratio was associated with a higher risk of kidney stone recurrence. Evidence Rating Level: 2 (Good)...
Baseline cannabis use may not be associated with abstinence from vaping
1. Among young adults, baseline cannabis use was not associated with nicotine vaping abstinence. 2. 12 weeks of varenicline were...
