Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

HbA1c may increase with switch from analogue to human insulin

1. In this retrospective cohort study, mean HbA1c levels decreased prior to systematic implementation of a program to switch from analogue to human insulin,...

Intensive blood pressure control may decrease risk of mild cognitive impairment

1. In this randomized controlled trial, intensive blood pressure lowering in elderly patients reduced the risk of developing Mild Cognitive Impairment (MCI) compared to...

Quick Take: Neutrophil–Lymphocyte Ratio as a Predictor of Kidney Function Decline Among Diabetes and...

Diabetic nephropathy is a major concern for patients with diabetes and pre-diabetes. The neutrophil-lymphocyte ratio (NLR) in kidneys has prognostic value for cancers and...

Dapagliflozin associated with reduced hospitalization rate for heart failure

1. Among patients with type 2 diabetes and established or multiple risk factors for cardiovascular disease (CVD), dapagliflozin was noninferior but did not significantly...

The LEAP trial: levodopa not associated with a disease-modifying effect in Parkinson’s disease

1. During an 80-week trial period of patient’s with early Parkinson’s disease (PD), there was no difference in the severity of symptoms between patients...

Hematopoietic stem cell transplantation reduces transcranial doppler velocities in children with sickle cell anemia

1. In this nonrandomized controlled intervention study, matched sibling donor stem cell transplantation (MSD-HSCT) was associated with lower transcranial doppler velocities (TCDs) at 1...

Robust survival benefit seen in lupus nephritis patients receiving renal transplant

1. For patients with Lupus nephritis end stage renal disease (LN ESRD), renal transplant reduced the risk of death by about 70%.2. The risk...

Aspirin use associated with reduction in cardiovascular events but increase in bleeding risk

1. In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not...

Fecal microbiota transplantation improves remission rates in ulcerative colitis

1. In this randomized controlled trial, patients who received a donor fecal microbiota transplant (FMT) had a higher rate of steroid-free remission at 8-weeks...

Disease modifying therapies likely to reduce conversion to secondary progressing multiple sclerosis

1. In this case-control cohort study, treatment with glatiramer acetate, interferon-beta, fingolimod, alemtuzumab, and natalizumab all led to reduced conversion to secondary progressive Multiple...

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