Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Heart failure readmission prevention program may have inadvertent consequences

1. In this interrupted time-series and survival analysis, rates of readmission after heart failure hospitalization decreased significantly after the implementation of the Hospital Readmission...

Lifestyle interventions and certain medications reduce risk of diabetes in high risk individuals

1. In this meta-analysis of studies that evaluated the rate of diabetes development in high risk individuals, lifestyle modifications (LSM) and certain classes of...

Dabigatran shown to be a safe and effective alternative to warfarin for reducing stroke...

1. The analysis of data from more than 50,000 patients showed that both dabigatran and warfarin were associated with similar amounts of bleeding and...

Cohort study suggests that functional impairment and decline are common in middle age

1. Functional impairment in activities of daily living (ADLs) and/or instrumental ADL (IADL), functional decline, and shifts between independence and functional impairment are all...

Rising price of health services drove increase in US health care spending

1. This ecological study found that between 1996-2013, annual US health care spending was largely related to increases in health care service price and...

Anti-TNF agents and thiopurines are associated with a slight increase in lymphoma in IBD...

1. In this retrospective cohort study, inflammatory bowel disease (IBD) patients on anti-tumor necrosis factor (TNF) agents or thiopurines had a higher rate of...

High intensity specialized intervention content following family-based intervention yields improved childhood weight loss

1. In this study of family-based intervention for childhood obesity, a specialized intervention incorporating social facilitation and behavioral skills was associated with improved weight...

ACE-inhibitors and statins do not impact albuminuria in adolescents with type 1 diabetes mellitus:...

1. In adolescents with type 1 diabetes mellitus, the albumin-to-creatinine ratio was not significantly changed by angiotensin-converting-enzyme (ACE) inhibitors alone, statins alone, or the...

Randomized trial suggests that self-administered latent tuberculosis treatment is noninferior to direct observation

1. Once-weekly isoniazid (INH) and rifapentine treatment for latent tuberculosis infection (LTBI) via self-administered therapy (SAT) had high completion rates in the United States...

Despite improving trends in lupus-related mortality, rates appear to remain high relative to non-lupus...

1. Over the 46-year study period, systemic lupus erythematosus (SLE) age-standardized mortality rates (ASMRs) did not decline as much as non-SLE ASMR, and there...
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