Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

Quick Take: HIV incidence among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine...

Previous studies have suggested that certain hormonal contraceptive methods, including intramuscular depot medroxyprogesterone acetate (DMPA-IM), may increase women’s susceptibility to HIV acquisition. In this...

The CREOLE trial: amlodipine and either hydrochlorothiazide or perindopril optimally lowers blood pressure in...

1. Black African patients with hypertension randomized to multiple two-drug combinations experienced greater blood pressure control when treated with amlodipine plus either hydrochlorothiazide or...

Alzheimer’s Disease imaging biomarkers slightly improve prediction of memory decline

1. In this prospective cohort, Alzheimer’s Disease biomarkers derived from imaging, namely amyloid, tau, and cortical thickness estimates, had a moderate impact in predicting...

Post-procedure stroke rates stable in TAVR patients in United States

1. In this retrospective cohort study, the rate of 30-day post-procedure stroke after transcatheter aortic valve replacement (TAVR) remained stable during the first five...

Being denied a wanted abortion may have detrimental health effects in the long term

1. The authors of this prospective cohort study found that women who were denied a wanted abortion were found to have higher rates of...

Quick Take: Association of Cortical Stimulation–Induced Seizure With Surgical Outcome in Patients With Focal...

Cortical stimulation during intracranial electroencephalography (EEG) is used in defining the epileptogenic zone in patients with epilepsy, with the aim of removing the seizure...

Quick Take: Assessment of the Safety of Pembrolizumab in Patients With HIV and Advanced...

Immunotherapies such as anti-PD-1 (anti-programmed cell death 1) and anti-PD-L1 (anti-programmed cell death ligand 1) are effective in treating numerous malignancies. The safety and...

Lisinopril and carvedilol reduce cardiotoxicity in breast cancer patients receiving trastuzumab and anthracyclines

1. In this randomized, placebo controlled study of HER2-positive breast cancer patients receiving trastuzumab, use of preventative lisinopril or carvedilol did not significantly reduce...

Quick Take: Ultra-processed food intake and risk of cardiovascular disease

The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat,...

Quick Take: Estimates of all cause mortality and cause specific mortality associated with proton...

Proton pump inhibitors (PPIs) are widely used in the management of gastroesophageal reflux. However, several studies have demonstrated serious adverse events associated with PPI...
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