Chronic Disease

Reports of high-impact chronic disease studies by medical professionals

In phase 3 trial, rituximab not associated with clinical improvement in patients with Myalgic...

1. In this randomized controlled trial, B-lymphocyte depletion through rituximab did not significantly improve fatigue symptoms of patients with ME/CFS compared to the placebo...

Quick Take: Efficacy and safety of biosimilar CT-P13 compared with originator infliximab in patients...

Anti-tumor necrosis factor (TNF) therapies are commonly used in the treatment of patients with moderate to severe Crohn’s disease. However, due to the high...

In utero administration of ivacaftor averts multiorgan disease in ferret model of cystic fibrosis...

1. A G551D missense mutation in the cystic fibrosis transmembrane conductance receptor (CFTR) is a genetic cause of cystic fibrosis (CF).2. In utero administration...

Quick Take: Combined Surgery and Extensive Intraoperative Peritoneal Lavage vs Surgery Alone for Treatment...

Gastric cancer is typically treated with surgical resection followed by chemotherapy. Peritoneal metastasis, caused by direct cancer cell dissemination, is the most common pattern...

Amyloid-PET imaging leads to changes in management in patients with dementia

1. In this prospective cohort study, changes in clinical management occurred after amyloid-PET imaging for a majority of patients with mild cognitive impairment (MCI)...

Quick Take: The contribution of cannabis use to variation in the incidence of psychotic...

Previous observational studies have supported a causal link between cannabis use and psychotic disorder. A recent meta-analysis has also shown a dose-response association with...

Shorter treatment regimen found to be noninferior for patients with multidrug resistant tuberculosis

1. A randomized control trial of patients with multidrug resistant tuberculosis found that shorter treatment regimens were noninferior to longer treatment regimens currently recommended...

Quick Take: Long-term outcome of surgery versus conservative management for recurrent and ongoing complaints...

Roughly 20% of patients affected by diverticulitis experience recurrent symptoms after being treated conservatively, without surgery. This is complicated by the fact that persistent...

Quick Take: Association Between the Development of Pediatric Voice Disorders and Singing in Children’sChoir

Singing has been thought to be protective against the development of voice disorders in children; however, there have been few studies evaluating this. In this...

Intervention to reduce low-value preoperative care for patients undergoing cataract surgery

1. In this quality improvement study carried out in Southern California, educational interventions to prevent low-value care before cataract surgery lead by a single...
licensing as small

All-time hits