Rivaroxaban and warfarin have similar safety and efficacy in mild atrial fibrillation-related ischemic stroke
1. In this randomized controlled trial, rivaroxaban and warfarin were similar in safety and efficacy when used to prevent early recurrence of stroke in...
Intensive blood pressure lowering linked to decreased mortality in patients with chronic kidney disease
1. In a meta-analysis of randomized trials evaluating blood pressure control in patients with stage 3-5 chronic kidney disease (CKD), more intensive blood pressure...
Re-analysis of evidence suggests that PSA screening significantly reduces the risk for death from...
1. PSA screening was associated with a reduction in risk for death from prostate cancer.
2. No differences in the effects of PSA screening were...
Sleep disordered breathing linked to impaired cognitive function
1. In this meta-analysis of available studies, prospective data demonstrated that sleep-disordered breathing (SDB) is associated with an increased risk of developing cognitive impairment.
2....
Lower target for blood pressure control linked to better cognition
1. In this prospective observational study of patients being treated for hypertension, lower systolic blood pressures were associated with slower cognitive decline.
2. The magnitude...
Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism
1. Although more extensive screening may detect more cases of occult cancer in patients with unprovoked venous thromboembolism (VTE) at the preliminary screening, it...
Canagliflozin reduces cardiovascular outcomes in patients with diabetes: The CANVAS
1. Canagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, significantly reduced the risk of the primary composite outcome of cardiovascular death, nonfatal myocardial infarction,...
Cerebral embolic protection devices not effective in surgical aortic valve repair
1. This randomized clinical trial showed that cerebral embolic protection devices did not significantly reduce the risk of CNS infarction among patients with calcific...
Plasma Epstein–Barr virus DNA useful for nasopharyngeal carcinoma screening
1. Asymptomatic study participants with persistently elevated serum Epstein-Barr virus (EBV) levels were diagnosed with nasopharyngeal carcinoma at rates higher than expected without screening.
2....
Osteoporosis medications may improve bone health in men receiving androgen deprivation therapy for prostate...
1. Bisphosphonates and denosumab increased bone mineral density (BMD) in men receiving androgen deprivation therapy (ADT) for nonmetastatic prostate cancer, with denosumab also showing...
