Cardiology

Reports of high-impact cardiology studies by medical professionals

Use of aspirin for primary prevention linked to increased risk of intracranial hemorrhage

1. In this systematic review and meta-analysis, use of low-dose aspirin in patients without symptomatic cardiovascular disease was linked with an increased risk of...

Unrecognized obstructive sleep apnea increases risk of postoperative cardiovascular events

1. In this prospective cohort study, severe but not moderate, unrecognized obstructive sleep apnea was associated with increased postoperative cardiovascular events in patients undergoing...

The EXTEND trial: neurological deficits decreased with thrombolysis up to 9 hours after stroke...

1. Patients presenting between 4.5 and 9 hours after stroke onset with viable brain tissue who received thrombolytic therapy had better neurological outcomes compared...

Cardiovascular outcomes of dialysis patients using phosphate binders with or without calcium

1. In this observational cohort study of patients with end-stage renal disease (ESRD) undergoing hemodialysis, there was no observed difference in cardiovascular events for...

Mavacamten shows promise for treating patients with obstructive hypertrophic cardiomyopathy

1. In this open-label clinical trial, mavacamten was found to reduce mean postexercise left ventricular outflow tract gradient after 12 weeks of treatment, which...

Patent foramen ovale associated with four-fold increased risk for ischemic stroke in patients with...

1. In this prospective cohort study, patients with symptomatic pulmonary embolism (PE) and a patent foramen ovale (PFO) were found to have a significantly...

Ticagrelor reversal agent provides immediate and sustained effect

1. A monoclonal antibody fragment to ticagrelor, PB2452, increased platelet function significantly in healthy patients given the oral P2Y12 inhibitor ticagrelor.2. Adverse effects were...

Trans-nasal cooling during cardiac arrest does not improve survival with good neurologic outcome

1. In this randomized controlled trial, intra-cardiac arrest, trans-nasal evaporative cooling did not improve survival with good neurologic outcome at 90 days compared to...

Quick Take: Individualised nutritional support in medical inpatients at nutritional risk

Malnutrition is a common occurrence in hospitalized patients. Current clinical practice guidelines recommend considering placing medical inpatients deemed to be at risk of malnutrition...

Quick Take: Association of Rivaroxaban With Thromboembolic Events in Patients With Heart Failure, Coronary...

Rivaroxaban is a selective direct factor Xa inhibitor that has been associated with improved outcomes in stable patients with chronic atherosclerotic cardiovascular disease and...
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