Lack of superiority of rivaroxaban for secondary prevention of embolic stroke of undetermined source
1. At a median follow-up of eleven months, rivaroxaban was not superior to aspirin for prevention of secondary stroke after an initial primary embolic...
Improved calculations suggest major changes to statin, aspirin, and blood pressure medication prescribing
1. Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.
2. Many Americans, especially those of African American...
Radial-artery grafts outperform saphenous-vein grafts when used in CABG: The RADIAL trial
1. Patients undergoing coronary artery bypass grafting (CABG) who received a radial-artery graft rather than a saphenous-vein graft (both groups also received an internal-thoracic-artery...
ECMO for severe ARDS does not improve mortality
1. Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared to conventional ventilation and...
Aldosterone antagonist therapy linked to reduced mortality following STEMI without heart failure
1. In this meta-analysis of available randomized clinical trials, use of aldosterone antagonist therapy in patients with preserved ejection fraction following ST-elevation myocardial infarction...
Amyloid-beta (1-40) is a strong predictor of mortality in acute coronary syndrome
1. Patients with the highest Aβ40 also had the worst non-ST-segment elevation acute coronary syndrome (NSTE-ACS) risk profile.
2. Greater all-cause mortality was observed in...
Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock
1. In this meta-analysis, addition of vasopressin to catecholamine vasopressors was associated with a lower risk of atrial fibrillation when compared to catecholamine monotherapy.
2....
Improved research methods needed to determine effectiveness of anti-obesity public health initiatives
1. Researchers found that amongst nearly 300 studies reporting the impact of policies, programs, or changes in built environment on controlling and preventing obesity,...
Sickle cell trait not linked to increased risk of ischemic stroke
1. In this meta-analysis of prospective population-based studies, sickle cell trait (SCT) was not associated with any difference in risk of first ischemic stroke.
2....
Addition of ticagrelor to aspirin significantly increased graft patency after elective CABG
1. In this randomized controlled trial, saphenous vein graft patency after elective CABG was significantly improved in patients treated with ticagrelor plus aspirin versus...
