Carotid endarterectomy and medical therapy reveal similar effectiveness in asymptomatic carotid stenosis
1. In patients with asymptomatic carotid stenosis, there was no significant difference between the comparative effectiveness of initial medical therapy versus carotid endarterectomy.
2. The...
Risk of positive COVID-19 diagnosis not associated with ACE inhibitor or angiotensin receptor blocker...
1. No association was found between angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker use and test-positivity for COVID-19.
Evidence Rating Level: 2 (Good)
Severe acute respiratory...
Multiple sclerosis patient at higher risk for cerebrovascular and cardiovascular disease
1. Compared to healthy matched controls, individuals with multiple sclerosis demonstrated significantly increased risk of cerebrovascular disease, acute coronary syndrome, cardiovascular disease-related mortality, and...
Risk of QTc prolongation with hydroxychloroquine therapy
1. Use of hydroxychloroquine with or without azithromycin to treat COVID-19 was frequently associated with QTc prolongation, with results being more pronounced for patients...
COVID-19 likely associated with high incidence of thromboembolic events
1. In this study of 12 decedents with COVID-19, deep venous thrombosis was observed in over half of the study population.
2. Pulmonary embolism was...
Antihypertensive medications and risk of COVID-19
1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a...
Diets rich in fruits and vegetables may protect heart health
1. In this observational study derived from the DASH feeding trial, both diets that were rich in fruits and vegetables were found to be...
Direct oral anticoagulants associated with lower risk of osteoporotic fracture versus warfarin
1. In this observational study, patients who received one of three direct oral anticoagulants (DOACs) were significantly less likely to have an osteoporotic hip...
Renin-angiotensin-aldosterone system inhibitors do not affect COVID-19 risk
1. Angiotensin-converting-enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) were not shown to affect the risk of COVID-19.
2. ACE inhibitors and ARBs were shown to...
Febuxostat not effective at delaying progression of carotid atherosclerosis in asymptomatic hyperuricemia
1. While there was no placebo control group, treatment with febuxostat for 24 months did not slow carotid atherosclerosis progression in Japanese individuals with...
