Discontinuation of statins in older patients with polypharmacy associated with increased cardiovascular events
1. Older patients with polypharmacy who discontinued statins had increased rates of admissions for heart failure, all-cause emergency hospital admissions, cardiovascular outcomes, and all-cause...
Ziltivekimab antagonism of IL-6 reduces inflammation and thrombosis in patients with atherosclerotic risk factors
1. Ziltivekimab lowered high-sensitivity CRP levels, a predictor of vascular events, compared to placebo in a dose-dependent manner.
2. Thrombotic biomarkers including fibrinogen, serum amyloid...
Reports of myocarditis in healthy adolescents after Pfizer-BioNTech COVID-19 Vaccination
1. In a case series, 7 healthy male adolescents aged 14-19 developed acute myocarditis or myopericarditis within 4 days of receiving the second dose of...
Genetic variants associated with unexplained sudden cardiac death in adult white and African American...
1. Nearly 20% of participants with unexplained sudden cardiac death carried pathogenic or likely pathogenic variants of cardiomyopathies and arrhythmia syndromes.
Evidence Rating Level: 2...
Carriers of genetic variants of inherited cardiomyopathies and arrhythmias associated with unexplained sudden cardiac...
1. In this study of White and African American adults who had unexplained sudden cardiac death, nearly 20% of individuals had pathogenic or likely...
Early initiation of rhythm-control for atrial fibrillation associated with lower risk of adverse cardiovascular...
1. Compared to patients only receiving rate-control treatment, those who received rhythm-control treatment within one year of diagnosis of atrial fibrillation had a lower...
Long‐term cardiovascular outcomes after pregnancy in women with heart disease
1. Women with heart disease had were at greater risk of cardiovascular events postpregnancy, compared to women without heart disease.
2. Tools that assess cardiovascular...
Implantable loop recorder associated with increased detection of atrial fibrillation post-ischemic stroke compared with...
1. In patients with recent ischemic stroke and no diagnosed atrial fibrillation (AF), there were increased AF diagnoses in those who received an implantable...
Risk factors for acute kidney injury and mortality in high risk patients undergoing cardiac...
1. In a retrospective cohort study, several pre-operative and operative factors were found to be associated with acute kidney injury and future mortality.
Evidence...
Treatment with Percutaneous Coronary Intervention versus Coronary Artery Bypass not associated with increased rate...
1. Rate of age-related memory decline did not significantly differ when comparing individuals over the age of 65 who underwent percutaneous coronary intervention (PCI)...
