Cardiology

Reports of high-impact cardiology studies by medical professionals

The REGROUP trial: endoscopic and open vein-graft harvest associated with similar outcomes

1. Among patients randomized to an open or endoscopic vein-graft harvest technique for coronary-artery bypass graft (CABG) surgery, there was no difference in major...

Medication co-payment vouchers for P2Y12 inhibitors not associated with reduced major adverse cardiovascular events

1. In this randomized controlled trial, medication vouchers were associated with a small increase in patient-reported persistence with P2Y12 inhibitors for patients who had...

Low-dose intracoronary alteplase unlikely to improve outcomes in STEMI patients treated with primary PCI

1. In this randomized controlled trial, low-dose intracoronary alteplase given early during primary percutaneous coronary intervention (PCI) for acute ST-Elevation Myocardial Infarction (STEMI) did...

Maternal obesity linked to increased risk of certain congenital heart defects

1. In this large population-based cohort study conducted in Sweden, maternal obesity status was linked to an increased prevalence rate of congenital heart defects...

Cardiac troponin elevation without definitive diagnosis associated with higher mortality

1. Among patients admitted for suspected acute coronary syndrome but discharged without a specific diagnosis, higher cardiac troponin levels were associated with elevated all-cause...

The VITAL trial: Omega-3 supplementation does not reduce risk of cardiovascular events

1. Healthy adult patients randomized to receive marine n-3 fatty acids (omega-3) experienced similar rates of adverse cardiovascular events as those receiving a placebo...

The REDUCE-IT trial: Icosapent ethyl reduces ischemic event risk in patients with hypertriglyceridemia despite...

1. After a median follow-up of 4.9 years, patients with elevated triglyceride levels despite statin use treated with icosapent ethyl had a lower risk...

PCI for unprotected left main coronary artery stenosis still performed infrequently

1. Revascularization with percutaneous coronary intervention (PCI) of unprotected left main (ULM) artery remains an infrequently performed procedure in the United States.2. The patients undergoing...

Aspirin alone likely safest antithrombotic therapy after bioprosthetic aortic valve replacement

1. Aspirin combined with warfarin was linked with increased bleeding but not less thromboembolism compared with aspirin alone after bioprosthetic aortic valve replacement.2. Dual...

Quick Take: Long-term Outcomes of Tetralogy of Fallot: A Study From the Pediatric Cardiac...

Tetralogy of Fallot (TOF) is the most common congenital cyanotic heart disease. Surgical repair of TOF was shown in 1954 to have a long-term...

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