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Bimekizumab is effective for active psoriatic arthritis in biologic-naïve adults
1. Significantly more patients in the bimekizumab group reached ACR50 at week 16 compared to the placebo. 2. Fungal infections...
Ferric derisomaltose may reduce heart failure-related hospitalizations
1. Risk of hospital admission was lower in the ferric derisomaltose group versus usual care. 2. Treatment-related adverse events were...
Monofilament suture does not reduce pregnancy loss compared to braided suture for cervical cerclage
1. Pregnancy loss was reported among 8.0% of patients in the monofilament suture group and 7.6% of patients in the...
Bivalirudin during and post-percutaneous coronary intervention reduces bleeding and mortality compared to heparin monotherapy
1. Bivalirudin during percutaneous coronary intervention plus high-dose infusion after demonstrated decreased all-cause mortality compared to heparin monotherapy. 2. Risk...
Low-dose low-molecular weight heparin comparable to intermediate-dose for risk of venous thromboembolism in peripartum women
1. Risk of venous thromboembolism in the antepartum and postpartum period was comparable between the intermediate- and low-dose low-molecular weight...
Balloon catheters are comparable to vaginal prostaglandins for induction of labour
1. There was no significant difference between groups in terms of rate of caesarean delivery, caesarean delivery for failure to...
Intensive blood pressure control post-endovascular thrombectomy after acute ischemic stroke linked with worse clinical outcomes
1. More intensive blood pressure targets were associated with poor functional outcome at 90 days, neurological deterioration, and major disability...
All-oral regimen with delamanid, linezolid, levofloxacin, and pyrazinamide is effective for fluoroquinolone-sensitive multidrug-resistant tuberculosis
1. At 24 months, treatment success rate was numerically greater in the shorter-regimen group versus conventional therapy, satisfying the noninferiority...
Timing of daily antihypertensives does not change cardiovascular outcomes
1. The primary composite cardiovascular endpoint was similar among patients in the evening and morning dose groups. 2. Self-reported adverse...
Chlorhexidine and povidone-iodine equally effective for skin antisepsis of open fractures undergoing surgical fixation
1. Povidone-iodine and chlorhexidine were comparable in terms of surgical site infections. 2. 16% of patients in both groups required...
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