Endocrinology

Reports of high-impact endocrinology studies by medical professionals

Quick Take: Glucagon Receptor Antagonist–Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age

Glucagon-containing α-cells are important for regulating glucose homeostasis along with insulin-secreting β-cells. Glucagon receptor antagonists (GRAs) hold potential as antidiabetic therapies, but there is...

Sodium-glucose cotransporter-2 inhibitors may be linked to Fournier gangrene

1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described.2....

Sex, hemoglobin A1c, psychosocial factors associated with type 1 diabetes-related distress

1. In this prospective cohort study, adolescents with type 1 diabetes (T1D) were noted to be more likely to have persistently elevated distress levels...

Quick Take: Effect of basal insulin supplement therapy on diabetic retinopathy in short‐duration type...

Better treatments are needed for diabetic retinopathy (DR), a microvascular complication of diabetes. Intensive glycemic treatment can delay DR onset and progression, but it...

Metformin may help patients maintain long-term weight loss

1. Continued use of metformin beyond the randomized controlled trial was found to be predictive of long-term weight loss among participants who had lost...

Quick Take: The burden of health conditions for middle-aged and older adults in the...

Understanding the burden of health conditions in older adults in the U.S. is essential in addressing the healthcare demands of this patient population. This...

Internal medicine interns spending minority of time on direct inpatient care

1. In this direct observational study, first year internal medicine residents (interns) spent only 13% of their time on direct patient care, while spending...

Quick Take: Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injection Regimens in Children and...

Multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) are two forms of intensive insulin regimens utilized by patients with type 1 diabetes....

Quick Take: Effect of a Multifaceted Quality Improvement Intervention on the Prescription of Evidence-Based...

In low and middle-income countries, the implementation of evidence-based therapies for cardiovascular disease, including the use of statins, antiplatelet therapy and anti-hypertensive medications, remains...

In utero administration of ivacaftor averts multiorgan disease in ferret model of cystic fibrosis...

1. A G551D missense mutation in the cystic fibrosis transmembrane conductance receptor (CFTR) is a genetic cause of cystic fibrosis (CF).2. In utero administration...
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