Mazdutide significantly reduces weight in adults with overweight or obesity
1. In this randomized controlled trial, weekly administration of Mazdutide resulted in significant weight reduction in adults classified as overweight...
Endocrinology
Reports of high-impact endocrinology studies by medical professionals
Type 2 diabetes and abnormal amyloid concentrations are associated with accelerated brain atrophy
1. Type 2 diabetes and abnormal amyloid-β concentration (low Aβ42:Aβ40 ratio) in the cerebrospinal fluid were associated with accelerated brain...
Artificial intelligence based clinical decision systems are safe and effective for diabetes management
1. In this randomized clinical trial of adults with type 2 diabetes (T2D), the artificial intelligence-based insulin clinical decision support...
Sodium-glucose cotransporter 2 inhibitors may decrease risk of serious liver events in patients with cirrhosis
1. Use of Sodium-Glucose Cotransporter 2 (SGLT-2) inhibitors among adults with cirrhosis receiving diuretic therapy was associated with lower incidence...
Weighted vests and resistance training confer similar outcomes for bone density in the elderly
1. In this 12-month randomized clinical trial, weight loss (WL)-associated bone loss occurred in older adults with obesity, regardless of...
Volumetric diet and time-restricted eating demonstrate similar outcomes for weight reduction
1. In this randomized controlled trial comparing the volumetrics diet (VD) and time-restricted eating (TRE), both interventions led to significant...
Tirzepatide-associated improvements in cardiometabolic risk factors linked to degree of weight loss
1. In this post-hoc analysis of the SURMOUNT-1 trial, there was a mostly linear relationship between percentage change in weight...
Semaglutide may improve cardiovascular outcomes versus empagliflozin in patients with diabetes
1. In this retrospective cohort study, treatment with semaglutide resulted in nominally lower incidence of the composite of death, myocardial...
Midlife weight loss is associated with decreased risk of mortality and chronic disease
1. Participants with sustained midlife weight loss from nonsurgical and nonpharmacological intervention had a decreased risk of chronic diseases beyond...
Semaglutide improves walking ability in patients with peripheral artery disease and type 2 diabetes
1. Maximum walking distance at 52 weeks was significantly improved with semaglutide. 2. There were fewer treatment-related serious adverse events...