Pediatric usage of SSRI’s associated with increased risk of type 2 diabetes
1. Selective serotonin reuptake inhibitor use among children and adolescents with public health insurance was found to be associated with a mildly increased risk...
Better glucose control with closed-loop system in children with type 1 diabetes
1. The closed-loop system maintained glucose levels within the target range for a significantly greater percentage of time for children with type 1 diabetes.
2....
Selpercatinib may provide an effective response against RET-mutated thyroid cancer
1. Selpercatinib, a highly selective RET kinase inhibitor, was effective in antitumor activity against medullary thyroid cancer.
2. Selpercatinib caused low-grade toxic effects in patients...
Indigenous individuals with diabetes screened less and have poorer glycemic and lipid control than...
1. Indigenous individuals with diabetes were found to have poorer blood sugar and lipid levels, as well as higher use of diabetes medications, compared...
Diet and gastric bypass have similar metabolic benefits in diabetic patients
1. Diet alone had nearly identical benefits on insulin sensitivity compared to gastric bypass surgery.
2. The metabolic benefits from diet and gastric bypass surgery...
Iodine deficiency associated with adverse fetal and gestational outcomes
1. Low iodine intake associated with decreased subfecundity, reduced fetal growth, increased preterm delivery, and increased preeclampsia.
Evidence Rating Level: 2 (Good)
The thyroid gland is...
Metformin associated with retention of cognitive ability and reduced white matter loss in pediatric...
1. Metformin was found to be safe and tolerable in survivors of pediatric brain tumors.
2. Metformin was associated with retention of memory and processing...
Sodium glucose cotransporter-2 inhibitor use associated with increased risk of diabetic ketoacidosis
1. The use of sodium-glucose cotransporter-2 (SGLT-2i) increased study participants’ risk of diabetic ketoacidosis (DKA) hospital presentations when compared to dipeptidyl peptidase 4 inhibitors
2....
Modestly lower carbohydrate diet not associated with improved outcomes related to gestational diabetes
1. A modestly lower carbohydrate diet neither increased ketonemia nor improved glycemic control in pregnant women
Evidence Rating Level: 2 (Good)
Although meta-analyses have shown significant...
Kidney function in type 1 diabetes does not benefit from allopurinol therapy
1. Serum urate reduction with allopurinol was not shown to clinically benefit kidney function among patients with type 1 diabetes and early-to-moderate diabetic kidney...
