Endocrinology

Reports of high-impact endocrinology studies by medical professionals

SGLT-2 inhibitors and GLP-1 agonists associated with better mortality outcomes than DPP-4 inhibitors for...

1. SGLT-2 or GLP-1 agonists were associated with lower mortality than DPP-4 inhibitors, placebo, or no treatment. 2. Use of DPP-4 inhibitors was not associated...

Intensive LDL-C lowering reduces mortality in patients with higher baseline LDL-C

1. In this systematic review and meta-analysis, more intensive compared with less itensive LDL-C lowering was associated with a greater reduction in risk of...

No association of overweight childhood and adult type 2 diabetes risk after weight loss

1. Compared to men who were never overweight, those overweight at age 7 who returned to a normal body mass index (BMI) by age...

Barber facilitated health promotion reduces blood pressure among black male barber patrons

1. Non-Hispanic black male barber patrons prescribed antihypertensive therapy with barber encouragement along with lifestyle modification experienced greater reductions in blood pressures compared to...

Transgender youth found to have higher rates of mental health disorders

1. Transgender and/or gender nonconforming (TGNC) children and adolescents had higher prevalence of mental health disorders compared to their cisgender peers. 2. Anxiety disorders, attention...

Single PSA screening increases prostate cancer detection but does not change mortality

1. In this randomized controlled trial, men who were screened with a single PSA test had higher diagnoses of prostate cancer than those who...

Physical, physiological benefits of hormonal treatment in gender dysphoria

1. In a limited systematic review, hormonal therapy with gonadotropin-releasing hormone analogs (GnRHas) produced some suppression of secondary sexual function, with more success in...

Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock

1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality...

Adjunctive glucocorticoid therapy does not lower mortality in septic shock

1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion, did not have...

Effect of low-fat vs low-carbohydrate diet on weight loss in overweight adults

1. No significant difference in weight change between a healthy low-fat diet and a healthy low-carbohydrate diet. 2. Genotype pattern or insulin secretion was not...
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