Endocrinology

Reports of high-impact endocrinology studies by medical professionals

Genetic variants of increased waist-to-hip ratios associated with diabetes and coronary disease

1. A polygenic risk score for increased waist-to-hip ratio (WHR) was developed from over 200 risk loci. 2. Polygenic risk scores for higher WHR were...

Quick Take: Pegbelfermin (BMS-986036), a PEGylated Fibroblast Growth Factor 21 Analogue, in Patients with...

Non-alcoholic steatohepatitis (NASH), the most common chronic liver disease in the United States, puts patients at increased risk of developing cirrhosis and hepatocellular carcinoma....

Liraglutide significantly reduces risk for major cardiac events in elderly patients with diabetes

1. A significant reduction in major cardiac events among elderly patients was seen in the liraglutide treatment group.2. The risk reduction of adverse cardiac events...

Nurse Practitioners and Physician Assistants can effectively manage chronic conditions, fill gaps in primary...

1. In this study, no significant differences were seen in the diabetes outcomes of patients managed by nurse practitioners (NPs) or physician assistants (PAs)...

Diabetes patients with high-deductible health care plans may delay seeking crucial care

1. In this study, patients with high-deductible health care plans were more likely to delay seeking care for the treatment of macrovascular complications of...

Quick Take: Performance of a Multigene Genomic Classifier in Thyroid Nodules With Indeterminate Cytology:...

In the evaluation of thyroid nodules, fine needle aspirate (FNA) cytology can classify most thyroid nodules as benign or malignant; a minority of results,...

Quick Take: Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor...

Glucagon-like peptide-1 (GLP-1) potentiates the release of insulin from pancreatic beta cells in a glucose-dependent manner. While pharmacologic studies have shown that GLP-1 delays...

Quick Take: Effect of lorcaserin on prevention and remission of type 2 diabetes in...

There is a strong relationship between body weight and the risk of developing diabetes. Lorcaserin is a selective serotonin 2C receptor agonist that suppresses...

Cost a key consideration of WHO guidelines for diabetes treatment intensification

1. WHO guidelines recommend selecting sulfonylureas as the single best second-line agent for Type 2 Diabetes Mellitus (T2DM) patients.2. Authors of a commentary on...

Improved cardiovascular health associated with lower incidence of dementia in older adults

1. In this prospective cohort study, older patients with more optimal cardiovascular (CV) health metrics had a lower rate of developing dementia in a...
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