Strict glucose control does not improve outcomes in acute ischemic stroke patients
1. In this randomized controlled trial, intensive hyperglycemia treatment did not lead to improved outcomes compared to standard treatment in patients 90 days after...
Quick Take: Association between androgen deprivation therapy use and diagnosis of dementia in men...
Androgen deprivation therapy (ADT) is used in the treatment of prostate cancer, either alone or in combination with other treatment modalities. ADT, however, is...
The VADT-F trial: major cardiovascular events or death are not reduced in diabetics with...
1. In a 15-year observational cohort study of type 2 diabetics treated with intensive compared to standard glucose control therapy the risk of major...
Quick Take: Glucagon Receptor Antagonist–Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age
Glucagon-containing α-cells are important for regulating glucose homeostasis along with insulin-secreting β-cells. Glucagon receptor antagonists (GRAs) hold potential as antidiabetic therapies, but there is...
Sodium-glucose cotransporter-2 inhibitors may be linked to Fournier gangrene
1. In this descriptive case series, 55 cases of patients with diabetes who developed Fournier gangrene while using sodium-glucose cotransporter-2 (SGLT2) inhibitors are described.2....
Sex, hemoglobin A1c, psychosocial factors associated with type 1 diabetes-related distress
1. In this prospective cohort study, adolescents with type 1 diabetes (T1D) were noted to be more likely to have persistently elevated distress levels...
Quick Take: Effect of basal insulin supplement therapy on diabetic retinopathy in short‐duration type...
Better treatments are needed for diabetic retinopathy (DR), a microvascular complication of diabetes. Intensive glycemic treatment can delay DR onset and progression, but it...
Metformin may help patients maintain long-term weight loss
1. Continued use of metformin beyond the randomized controlled trial was found to be predictive of long-term weight loss among participants who had lost...
Quick Take: The burden of health conditions for middle-aged and older adults in the...
Understanding the burden of health conditions in older adults in the U.S. is essential in addressing the healthcare demands of this patient population. This...
Internal medicine interns spending minority of time on direct inpatient care
1. In this direct observational study, first year internal medicine residents (interns) spent only 13% of their time on direct patient care, while spending...
