Hydrocortisone plus fludrocortisone decreases mortality in adults with septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation receiving hydrocortisone plus fludrocortisone had a lower 90-day all-cause mortality...
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion, did not have...
Effect of low-fat vs low-carbohydrate diet on weight loss in overweight adults
1. No significant difference in weight change between a healthy low-fat diet and a healthy low-carbohydrate diet.
2. Genotype pattern or insulin secretion was not...
First-degree family history of breast cancer associated with increased risk of breast cancer in...
1. In this prospective cohort study, first-degree family history of breast cancer was associated with increased risk of breast cancer in women 65 years...
Improved islet encapsulation device for the treatment of type 1 diabetes [PreClinical]
1. A device for islet transplantation for type 1 diabetes was designed and demonstrated to be safe and retrievable in animal models.
2. When tested...
Living kidney donation associated with some increased health risks
1. Living kidney donation was associated with higher diastolic blood pressure, lower estimated glomerular filtration rates, and increased relative risk of preeclampsia and end-stage...
First trimester exposure to antithyroid drugs associated with increased risk of birth defects
1. First trimester exposure to anytithyroid drugs (ATDs) was associated with a greater risk of congenital malformations, especially for pregnant women who were given...
Longer lactation duration linked to lower risk of diabetes in women
1. In this 30-year prospective cohort study, self-reported duration of lactation in women of childbearing age was associated with a lower risk of development...
Thyroid hormone supplementation may be a promising treatment for idiopathic pulmonary fibrosis [PreClinical]
1. An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis.
2. Following the treatment of various mouse...
Normal tissue BRCA1 methylation associated with risk for high-grade ovarian cancer
1. BRCA1 promoter methylation in normal white blood cells (WBCs) was linked to risk for high-grade serous ovarian cancer (HGSOC).
2. BRCA1 methylation was detected...
