Golimumab effective at preserving insulin production in type 1 diabetes
1. In this randomized, double-blind, phase two trial, the use of golimumab led to more C-peptide production, indicative of improved endogenous function, compared to...
No mortality benefit found for in-home glucose-lowering medications among those with COVID-19
1. In-home glucose-lowering medications were not associated with increased mortality or complications among those with COVID-19.
Evidence Rating Level: 2 (Good)
Diabetes is one of the...
Semaglutide associated with dose-dependent weight loss and resolution of nonalcoholic steatohepatitis
1. Nonalcoholic steatohepatitis (NASH) resolution without worsening of fibrosis occurred in a significantly greater percentage of patients who received semaglutide versus placebo, but the...
Finerenone may lower risk of chronic kidney disease progression and cardiovascular events
1. Finerenone treatment lowered the risk of chronic kidney disease (CKD) progression in patients diagnosed with type 2 diabetes and advanced CKD.
2. Treatment with...
Elevated plasma ACE2 associated with an increased risk of poor cardiovascular outcomes
1. Increased levels of circulating ACE2 were associated with greater risk of cardiovascular and non-cardiovascular death, heart failure, myocardial infarction, stroke, and diabetes.
2....
Postpartum plasma metabolomic profile among women with preeclampsia and preterm delivery: implications for long-term...
1. Mothers with preterm deliveries have significantly different levels of metabolites among them compared to term mothers.
2. There are different levels of metabolites among...
Association of the amount and pattern of physical activity with arterial stiffness: The Maastricht...
1. Higher amounts of weekly physical exercise were associated with better carotid-to-femoral pulse wave velocities but not with carotid distensibility, which are both markers...
Early changes in albuminuria with Canagliflozin predicts kidney and cardiovascular outcomes
1. Among patients with type 2 diabetes mellitus and chronic kidney disease being treated with canagliflozin, earlier reductions in albuminuria were associated with a...
Pediatric usage of SSRI’s associated with increased risk of type 2 diabetes
1. Selective serotonin reuptake inhibitor use among children and adolescents with public health insurance was found to be associated with a mildly increased risk...
Better glucose control with closed-loop system in children with type 1 diabetes
1. The closed-loop system maintained glucose levels within the target range for a significantly greater percentage of time for children with type 1 diabetes.
2....
