#VisualAbstract: Association of Office and Ambulatory Blood Pressure With Mortality and Cardiovascular Outcomes

1. In this prospective cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite...

#VisualAbstract: Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome

1. Triglyceride levels in familial chylomicronemia patients were notably reduced when treated with the apolipoprotein C-III antisense mediated inhibitor volanesorsen compared to placebo treated...

#VisualAbstract: A Pivotal Response Treatment Package for Children With Autism Spectrum Disorder

1. Pivotal response treatment (PRT) is an intervention designed to increase motivation to interact by rewarding effort with natural reinforcement. Children with autism spectrum...

#VisualAbstract: Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES)

Studies have shown that intrahepatic cholestasis of pregnancy is associated with poor birth outcomes and neonatal unit admission. Ursodeoxycholic acid, which increases bile acid...

#VisualAbstract: Effect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression...

1.  In this randomized controlled trial, patients with Major depressive disorder with psychotic features who were stable on olanzapine and sertraline showed higher relapse...

#VisualAbstract: Eculizumab in Aquaporin-4–Positive Neuromyelitis Optica Spectrum Disorder

1. In this randomized control trial of neuromyelitis optica spectrum disorder (NMOSD) patients with aquaporin-4 antibodies (AQP4-IgG), those randomized to receive the eculizumab complement...

#VisualAbstract: Liraglutide in Children and Adolescents with Type 2 Diabetes

1. In children with type 2 diabetes (T2DM) on metformin, those randomized to liraglutide had better glycemic control after 26 weeks compared to placebo...

#VisualAbstract: An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

1. In relatives of patients with type 1 diabetes (T1DM) at risk for disease development, randomization to teplizumab delayed time to T1DM diagnosis compared...

#VisualAbstract: Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

1. Previously untreated chronic lymphocytic leukemia (CLL) patients experienced increased progression-free and overall survival when treated with ibrutinib-rituximab compared to current standard chemoimmunotherapy.2. Rates...

#VisualAbstract: Immediate Transfusion in African Children with Uncomplicated Severe Anemia

1. In African children with uncomplicated severe anemia, immediate blood transfusion did not notably alter patient mortality at 1- or 6-months post treatment compared...
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