Preclinical

1. This case-control study of 689 patients with frontotemporal dementia demonstrated that visual artistic creativity emerged in 17 patients (2.5%),...

1. There was no association detected between PCSK9 gene variants and alterations in cardiac morphology. 2. The odds of having...

1. In this secondary analysis of the RESCUE trial, targeted interleukin 6 (IL-6) ligand inhibition with ziltivekimab was associated with...

1. Certain sleep phenotypes, such as those with the familial natural short sleepers (FNSS) mutation, anecdotally do not exhibit the...

1. More patients with systemic lupus erythematosus (SLE) who received high doses of iberdomide achieved SRI-4 response compared to placebo...

1. The adeno-associated virus 5 (AAV5)-based gene therapy, valoctocogene roxaparvovec (AAV5-hFVIII-SQ), resulted in sustained factor VIII production, reduced bleeding rates,...

1. LentiGlobin gene therapy resulted in sustained production of the modified anti-sickling hemoglobin, HbAT87Q. 2. LentiGlobin led to reduced hemolysis...

1. Betibeglogene autotemcel (beti-cel) gene therapy resulted in sustained hemoglobin A with a T87Q amino acid substitution (HbAT87Q) in non-β0/β0...

1. Children of mothers who were exposed to anti-psychotics during pregnancy, compared to those never exposed, did not have an...

1. There was no difference in follow-up symptom severity between patients who received immediate or delayed antibiotics for respiratory tract...