Familial natural short sleep mutations may reduce Alzheimer’s Disease pathology in mice [PreClinical]
1. Certain sleep phenotypes, such as those with the familial natural short sleepers (FNSS) mutation, anecdotally do not exhibit the...
1. Certain sleep phenotypes, such as those with the familial natural short sleepers (FNSS) mutation, anecdotally do not exhibit the...
1. More patients with systemic lupus erythematosus (SLE) who received high doses of iberdomide achieved SRI-4 response compared to placebo...
1. The adeno-associated virus 5 (AAV5)-based gene therapy, valoctocogene roxaparvovec (AAV5-hFVIII-SQ), resulted in sustained factor VIII production, reduced bleeding rates,...
1. LentiGlobin gene therapy resulted in sustained production of the modified anti-sickling hemoglobin, HbAT87Q. 2. LentiGlobin led to reduced hemolysis...
1. Betibeglogene autotemcel (beti-cel) gene therapy resulted in sustained hemoglobin A with a T87Q amino acid substitution (HbAT87Q) in non-β0/β0...
1. Children of mothers who were exposed to anti-psychotics during pregnancy, compared to those never exposed, did not have an...
1. There was no difference in follow-up symptom severity between patients who received immediate or delayed antibiotics for respiratory tract...
1. Whole-genome sequencing for myeloid cancers, compared to standard cytogenic analysis, was able to more effectively risk-stratify cytogenic cases. 2....
1. Nonhuman primate vaccination with messenger RNA (mRNA)-1273 induced rapid neutralizing activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....
1. Lower RBFOX1 was associated with greater amyloid burden in the prefrontal cortex. 2. Reduced RBFOX1 was associated with increased...
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