Post-traumatic stress disorder is associated with increased risk of mild cognitive impairment and dementia among United States Veterans
1. Among US Veterans, post-traumatic stress disorder (PTSD) and health-related social needs (HRSNs) were independently associated with a higher hazard of incident mild cognitive impairment, Alzheimer disease, or AD-related dementias,...
A long-term gonadotropin-releasing hormone agonist protocol may be associated with increased positive pregnancy outcomes in women with endometriosis undergoing frozen embryo transfer
1. Long-term gonadotropin-releasing hormone agonist (GnRH-a) protocol was associated with higher odds of positive pregnancy outcomes for women with endometriosis undergoing frozen embryo transfer (FET), compared with GnRH-antagonist (GnRH-ant), and...
Artificial intelligence (AI) capable of identifying uncommon gastrointestinal pathologies despite no targeted disease training
1. Dippel and colleagues evaluated AI detection models’ ability to identify infrequent pathological changes on gastrointestinal (GI) biopsies. 2. The best-performing model detected unfamiliar malignancies with high accuracy but missed...
Prognostic associations of anthropometric indices vary by clinical outcomes
1. Prognostic associations of anthropometric indices varied according to clinical outcomes. The body roundness index showed the highest discrimination for atherosclerotic cardiovascular disease, body mass index for all-cause mortality, and...
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Explore the Classics Series™
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient...
Child-Pugh Score: Prognosis, Classification & Cirrhosis Staging in Chronic Liver Disease [Classics Series]
1. The Child-Pugh score, derived from five clinical and lab measures (bilirubin, albumin, INR/prothrombin time, ascites, encephalopathy), is widely...
POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]
1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk...
