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2 Minute Medicine Rewind July 6, 2026
Efficacy of leflunomide in active Takayasu arteritis: a randomized double-blind placebo-controlled trial subtitle: Takayasu arteritis clinical trial in China (TACTIC) 1. Leflunomide (LEF) plus prednisone was well tolerated but did...
Behavioral support does not improve patient-directed opioid tapering success
1. In this randomized clinical trial, adding cognitive behavioural therapy (CBT) or self-management support to patient-centered opioid tapering did not improve taper success at 12 months. 2. However, CBT was...
Carvedilol linked to lower cirrhosis complication risk
1. In this retrospective cohort study, carvedilol was associated with a lower risk of major liver decompensation compared with nadolol and propranolol. 2. Carvedilol was also associated with lower risks...
Telemedicine may reduce interhospital transfers without increasing mortality
1. In this systematic review and meta-analysis, telemedicine was associated with lower rates of interhospital transfer among both pediatric and adult patients. 2. Across most studies, telemedicine reduced or did...
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Explore the Classics Series™
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization...
Breast cancer survivors may have a lower risk of Alzheimer’s dementia
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free...
Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second...
