Methadone initiation linked to lower mortality compared to buprenorphine-naloxone after opioid overdose
1. In this retrospective cohort study examining people who had survived a recent opioid overdose, initiating methadone was associated with lower all-cause mortality over the following year compared with initiating...
Continuous femoral nerve block is not superior to continuous adductor canal block for postoperative pain following ACL reconstruction
1. Continuous femoral nerve block (CFNB) was not superior to continuous adductor canal block for the primary outcome of average postoperative pain over 48 hours following ACL reconstruction, despite CFNB...
Uterine-Sparing Mesh Repair Outperforms Hysterectomy for Prolapse
1. Vaginal mesh hysteropexy resulted in fewer composite treatment failures than vaginal hysterectomy with uterosacral suspension over 10 years of follow-up in women with symptomatic uterovaginal prolapse. 2. Failure rates...
Daraxonrasib showed antitumor activity in previously treated RAS-mutant non–small-cell lung cancer
1. In patients with previously treated advanced RAS-mutant non–small-cell lung cancer, daraxonrasib produced objective responses in approximately one-third of subjects across the evaluated dose groups. 2. Antitumor activity remained similar...
2MM+ membership
View full plan →The full 2MM experience.
- 100+ physician-written reports monthly
- EvidencePulse™ + HypeCheck™
- Ad-free reading + newsletters
Then $4.99/month. Manage renewal from your account.
License Our Award-Winning Physician-Written Medical News and Visual Abstracts
2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.
Explore the Classics Series™
![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient...
Child-Pugh Score: Prognosis, Classification & Cirrhosis Staging in Chronic Liver Disease [Classics Series]
1. The Child-Pugh score, derived from five clinical and lab measures (bilirubin, albumin, INR/prothrombin time, ascites, encephalopathy), is widely...
POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]
1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk...
