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Patient-reported outcome measures in cardiovascular disease have limited validation of psychometric properties
1. In 50 patient-reported outcome measures evaluated, only a small minority reported the validation of all Food and Drug Administration (FDA)-recommended psychometric properties. 2. Patient-reported outcome measures (PROMs) rarely had...
Acetazolamide increases rate of successful decongestion in patients with acute decompensated heart failure
1. In addition to loop diuretic therapy, acetazolamide in patients with acute decompensated heart failure resulted in a greater incidence of successful decongestion. 2. Acetazolamide treatment was associated with higher...
Bionic pancreas reduces glycated hemoglobin levels compared to semi-automated insulin-delivery systems
1. Amongst patients with type 1 diabetes (T1D), a bionic pancreas caused a reduction in glycated hemoglobin levels over a 13-week period. 2. In comparison to the bionic pancreas group,...
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Explore the Classics Series
The ACCORD trial: Intensive glucose control associated with increased mortality [Classics Series]
1. Previous studies suggest that intensive blood glucose control reduces the risk of microvascular complications, though questions remained regarding the impact on macrovascular complications and...
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Perioperative gabapentin use associated with adverse outcomes for older adults
1. In this cohort study, perioperative gabapentin for multimodal analgesia in older adults undergoing major surgery was associated with an...
Individuals with autoimmune diseases may have an increased risk for cardiovascular diseases
1. An increased incidence of new cardiovascular disease was seen in individuals with autoimmune disease compared to those without. 2....
Commercial weight loss programs lead to greater weight loss than do-it-yourself methods
1. In this study, a commercial weight loss program resulted in greater weight loss at 3 and 12-months compared to...
Aspirin associated with significantly higher rate of symptomatic venous thromboembolism compared to enoxaparin in patients undergoing hip or knee arthroplasty – the CRISTAL randomized trial
1. In this randomized controlled trial that included 9711 patients undergoing hip or knee arthroplasty, treatment with aspirin vs enoxaparin...
Early rhythm control for atrial fibrillation reduces the risk of adverse cardiovascular events
1. Early rhythm control for atrial fibrillation (AF) was associated with a significantly reduced risk of an adverse cardiovascular event. ...
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