2 Minute Medicine Rewind October 12, 2026
Low pressure (8 mmHg) pneumoperitoneum does not significantly reduce postoperative visual analog scale score after laparoscopic cholecystectomy: Randomized trial 1. Low-pressure pneumoperitoneum (LPP) at 8 mmHg did not significantly reduce...
Gepotidacin (Blujepa) is safe and effective in women with uncomplicated urinary tract infections
1. Gepotidacin (Blujepa) leads to rapid clinical response in female patients with uncomplicated urinary tract infections (uUTIs) and is generally well-tolerated. Evidence Rating Level: 2 (Good) uUTIs are exceedingly common...
Physician edits to artificial intelligence (AI)-generated messages to patients were associated with different response time burdens
1. Poursoltan and colleagues examined physician modifications to AI-generated patient messages and associated time burden. 2. Messages about clinical interpretations had the greatest per-message time burden, while frequent scheduling edits...
Male sex is associated with higher mortality among patients with hepatocellular carcinoma
1. In patients with hepatocellular carcinoma, male sex was associated with significantly higher mortality compared to female sex, but the relationship was heterogeneous across liver disease etiologies. Evidence Rating Level:...
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Explore the Classics Series™
![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
BI-RADS study identifies mammography features with high positive predictive values for carcinoma [Classics Series]
1. Lesions observed in mammography with spiculated margins, linear calcification morphology, irregular shape, segmental calcification distribution, or linear calcification...
Ottawa ankle rules reduce the rate of referral for ankle radiography [Classics Series]
1. The Ottawa ankle rules significantly reduced referral for ankle, but not foot, radiography in the emergency department. 2....
Canadian C-Spine Rules superior to NEXUS Low-Risk Criteria for detecting cervical-spine injuries [Classics Series]
1. The Canadian C-Spine Rule (CCR, Figure I) demonstrated higher sensitivity and specificity for cervical-spine injury compared to the...
