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Adverse pregnancy outcomes is associated with worse offspring cardiovascular health in early adulthood
1. Exposure to adverse pregnancy outcomes, particularly hypertensive disorders of pregnancy, was associated with worse cardiovascular health and early arterial injury among offspring in early adulthood. Evidence Rating Level: 2...
GLP-1 receptor agonists move from weight loss into the longevity conversation
GLP-1 receptor agonists move from weight loss into the longevity conversation GLP-1 receptor agonists are quickly shifting from niche metabolic drugs to something much broader in clinical conversation. What started...
2 Minute Medicine Rewind May 18, 2026
Determinants of treatment outcomes among hospitalised patients with skin and soft tissue infections: a prospective observational study 1. Delayed initiation of antibiotic therapy was strongly associated with treatment failure and...
Adjuvanted influenza vaccines and high-dose influenza vaccines may have similar effectiveness in adult patients
1. Adjuvanted influenza vaccines did not differ significantly in effectiveness compared to high-dose influenza vaccines against laboratory-confirmed influenza and influenza-related hospitalizations or emergency department (ED) visits in adult patients. Evidence...
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Explore the Classics Series™
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization...
Breast cancer survivors may have a lower risk of Alzheimer’s dementia
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free...
Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second...
