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Low-dose amitriptyline effective and well-tolerated for management of irritable bowel syndrome
1. Low-dose amitriptyline was associated with a marked decrease in IBS-SSS score at 6 months compared to placebo. 2. There were 5 serious adverse reactions (2 in the amitriptyline group...
Patisiran prevents functional decline in patients with cardiac amyloidosis
1. In this randomized controlled trial, patisiran demonstrated a reduction in functional capacity decline transthyretin amyloidosis (ATTR amyloidosis) with a cardiac component as compared to placebo. 2. Compared to placebo,...
#VisualAbstract: Amivantamab plus Chemotherapy in Non-Small Cell Lung Cancer with EGFR Exon 20 Insertions Showed Superior Progression-Free Survival Than Chemotherapy Alone
Click here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article...
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The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated, seven-point, risk-stratification tool to identify patients at high risk of stroke following...
The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]
1. The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver...
The POISE trial: Perioperative use of beta-blockers [Classics Series]
1. The POISE trial was a randomized controlled trial exploring the effect of perioperative beta-blockers on cardiac death, nonfatal...
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