Frailty in older adults with atrial fibrillation is multifactorial and associated with metabolic and cognitive factors
1. Among older adults with atrial fibrillation, higher homocysteine and C-reactive protein levels, poorer cognitive performance, and greater nutritional risk were independently associated with frailty. Evidence Rating Level: 2 (Good)...
Artificial intelligence (AI) capable of identifying uncommon gastrointestinal pathologies despite no targeted disease training
1. Dippel and colleagues evaluated AI detection models’ ability to identify infrequent pathological changes on gastrointestinal (GI) biopsies. 2. The best-performing model detected unfamiliar malignancies with high accuracy but missed...
2 Minute Medicine Rewind September 28, 2026
Probiotics and Risk of Death, Necrotizing Enterocolitis, and Sepsis in Very Preterm Infants 1. Probiotic supplementation was associated with a lower risk of death and/or necrotizing enterocolitis in very preterm...
Nirsevimab (Beyfortus) may reduce severe respiratory syncytial virus infections among infants
1. In this large case-control study across 7 tertiary pediatric hospitals, receiving Nirsevimab (Beyfortus) among symptomatic infants with respiratory syncytial virus (RSV) significantly reduced the burden of severe disease and...
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Explore the Classics Series™
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated clinical tool that estimates the short-term risk of stroke following a transient...
Child-Pugh Score: Prognosis, Classification & Cirrhosis Staging in Chronic Liver Disease [Classics Series]
1. The Child-Pugh score, derived from five clinical and lab measures (bilirubin, albumin, INR/prothrombin time, ascites, encephalopathy), is widely...
POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]
1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk...
