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150 minutes of moderate-to-vigorous physical activity per week may reduce cardiovascular risk in overweight or obese adults
1. In adults with overweight or obesity, performing at least 150 minutes of moderate-to-vigorous physical activity per week reduces cardiovascular risk, whether activity is concentrated in 1–2 days or distributed...
![2 Minute Medicine: Pharma Roundup: Price Hikes, Breakthrough Approvals, Legal Showdowns, Biotech Expansion, and Europe’s Pricing Debate [May 12nd, 2025]](data:image/svg+xml;nitro-empty-id=NzM3OjEzNTE=-1;base64,PHN2ZyB2aWV3Qm94PSIwIDAgMSAxIiB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==)
2 Minute Medicine: Pharma Roundup – Merck and Mayo Clinic’s AI precision medicine lab, Novartis’ remibrutinib hits Phase III hive endpoint, FDA grants priority review for iberdomide in myeloma, oral infigratinib boosts growth velocity in achondroplasia, and shingles vaccine/sildenafil linked to lower Alzheimer’s risk [February 2026]
Merck and Mayo Clinic launch AI-driven precision medicine partnership Merck and Mayo Clinic have officially kicked off a landmark R&D agreement that pairs one of the world’s top hospital systems...
Virtual reality rehabilitation is safe and feasible for upper extremity recovery after subacute ischemic stroke
1. Non-immersive virtual reality rehabilitation was feasible and safe but did not demonstrate superiority over equally intensive conventional physiotherapy for upper extremity recovery after subacute ischemic stroke. 2. Both rehabilitation...
Safety and efficacy of novel antibody-oligonucleotide therapy for myotonic dystrophy type 1
1. In this phase 1-2 randomized controlled trial involving adults with myotonic dystrophy type 1, del-desiran was well-tolerated in most patients 2. The treatment was also associated with decreased biochemical...
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![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](data:image/svg+xml;nitro-empty-id=ODYzOjE0MTY=-1;base64,PHN2ZyB2aWV3Qm94PSIwIDAgMSAxIiB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==)
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
Ablation may reduce stroke risk, death, heart failure hospitalization in patients with atrial fibrillation
1. In this systematic review and meta-analysis, catheter ablation was found to reduce overall risk of ischemic stroke, hospitalization...
Breast cancer survivors may have a lower risk of Alzheimer’s dementia
1. In this retrospective cohort study, breast cancer survivors had a lower risk of Alzheimer’s dementia compared with cancer-free...
Repeated medial branch blocks do not improve pain outcomes for thermal radiofrequency ablation
1. For patients with facet-mediated spine pain that achieve ≥80% pain relief after a medial branch block, a second...
