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The association between serum S100β levels and prognosis in acute stroke patients after intravenous thrombolysis
1. S100β levels 24 hours after IVT were independently associated with HT, infarct volume, and prognosis in stroke patients Evidence Rating Level: 2 (Good) Intravenous thrombolysis (IVT) is the treatment...
Pomalidomide effective in reducing epistaxis in hereditary hemorrhagic telangiectasia
1. Among patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide significantly reduced the severity of epistaxis and improved quality of life. 2. Pomalidomide was associated with neutropenia, constipation, and rash. Evidence...
Ziresovir reduces the severity of respiratory syncytial virus in hospitalized infants
1. Ziresovir, an antiviral drug targeted at respiratory syncytial virus (RSV), was superior to placebo in reducing signs and symptoms of hospitalized young children with RSV infection. 2. The incidence...
Combination of doxorubicin-trabectedin with trabectedin improves leiomyosarcoma outcomes
1. In patients with advanced leiomyosarcoma, a regimen of doxorubicin-trabectedin was superior to doxorubicin alone in improving progression-free and overall survival. 2. Trabectedin was associated with higher incidence and severity...
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The ABCD2 score: Risk of stroke after Transient Ischemic Attack (TIA) [Classics Series]
1. The ABCD2 score is a validated, seven-point, risk-stratification tool to identify patients at high risk of stroke following...
The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]
1. The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver...
The POISE trial: Perioperative use of beta-blockers [Classics Series]
1. The POISE trial was a randomized controlled trial exploring the effect of perioperative beta-blockers on cardiac death, nonfatal...
The NICE-SUGAR trial: Intensive glycemic control harmful in the ICU [Classics Series]
1. Intensive glycemic control in critically ill patients significantly increases 90-day mortality when compared to conventional glycemic control. 2....
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