Earlier menopause is associated with faster cognitive decline and greater late-life brain changes
1. Earlier age at menopause was associated with faster global and episodic memory decline, earlier Alzheimer disease diagnosis, and faster white matter hyperintensity accumulation in a 2,603-woman cohort followed for...
Giredestrant plus everolimus improves progression-free survival in treatment-resistant breast cancer
1. In this randomized controlled trial involving patients with disease progression during first-line treatment for breast cancer, giredestrant plus everolimus prolonged progression-free survival compared with standard endocrine therapy plus everolimus....
Antibiotics after appendectomy were not associated with reduced postoperative infections
1. Patients who underwent appendectomy for acute appendicitis had similar rates of postoperative infectious outcomes regardless of the use of postoperative antibiotics. 2. Symptom duration greater than two days, ASA...
Probiotic supplementation is associated with reduced risk of death and necrotizing enterocolitis among preterm infants
1. Probiotic supplementation was associated with a lower risk of death and/or necrotizing enterocolitis in very preterm infants. Evidence Rating Level: 2 (Good) Specific probiotics have been shown to reduce...
2MM+ membership
View full plan →The full 2MM experience.
- 100+ physician-written reports monthly
- EvidencePulse™ + HypeCheck™
- Ad-free reading + newsletters
Monthly plan: $4.99 USD per month after your 3-day free trial.
Start your 3-day free trial
Then $4.99/month. Manage renewal from your account.
License Our Award-Winning Physician-Written Medical News and Visual Abstracts
2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.
Explore the Classics Series™
![ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]](https://www.2minutemedicine.com/wp-content/uploads/2013/05/web-cover-classics-with-logo-medicine-BW-small-jpg-350x250.jpg){kind=logo}
EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
BI-RADS study identifies mammography features with high positive predictive values for carcinoma [Classics Series]
1. Lesions observed in mammography with spiculated margins, linear calcification morphology, irregular shape, segmental calcification distribution, or linear calcification...
Ottawa ankle rules reduce the rate of referral for ankle radiography [Classics Series]
1. The Ottawa ankle rules significantly reduced referral for ankle, but not foot, radiography in the emergency department. 2....
Canadian C-Spine Rules superior to NEXUS Low-Risk Criteria for detecting cervical-spine injuries [Classics Series]
1. The Canadian C-Spine Rule (CCR, Figure I) demonstrated higher sensitivity and specificity for cervical-spine injury compared to the...
