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Use of restorative hearing aid devices improves cognition and reduces risk of dementia in patients with hearing loss
1. The use of a restorative hearing aid in patients with hearing loss decreased the hazard of developing dementia by 19%. 2. Hearing aid use was associated with a 3%...
Maternal anemia in pregnancy may be associated with subsequent brain structure changes in offspring
1. Anemia during pregnancy associated with altered brain structure in children including smaller volumes of bilateral caudate, putamen and corpus callosum Evidence Rating Level: 2 (Good) It is estimated that...
Autologous tumour lysate-loaded dendritic cell vaccine in conjunction with standard treatment for glioblastoma may increase overall survival
1. Patients receiving autologous tumour lysate-loaded dendritic cell vaccine (DCVax-L) had a 20% relative reduction in death risk. 2. DCVax-L appears safe, with only 5 of 2,151 (0.2%) doses resulting...
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Explore the Classics Series
The ACCORD trial: Intensive glucose control associated with increased mortality [Classics Series]
1. Previous studies suggest that intensive blood glucose control reduces the risk of microvascular complications, though questions remained regarding the impact on macrovascular complications and...
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Low vitamin D is associated with increased risk of all-cause mortality
1. In this cohort study, low vitamin D measured at baseline was associated with an increased risk of death in...
Heavy smoking and alcohol use may be associated with insomnia and sleep dissatisfaction
1. In this cross-sectional database study, there was a greater prevalence of insomnia and dissatisfaction with sleep in individuals that...
Daily low dose aspirin may be associated with increased fall risk for geriatric patients
1. For healthy elderly patients randomized to take low-dose aspirin for 4 weeks, there was no difference in occurrence of...
All-oral regimen with delamanid, linezolid, levofloxacin, and pyrazinamide is effective for fluoroquinolone-sensitive multidrug-resistant tuberculosis
1. At 24 months, treatment success rate was numerically greater in the shorter-regimen group versus conventional therapy, satisfying the noninferiority...
Triple mRNA vaccination and previous COVID-19 exposure provide protection against the omicron variant
1. In this retrospective cohort study among prison residents and staff, mRNA vaccination and previous exposure provided more protection against...
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