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Artificial intelligence (AI) decision support software improved spirometry diagnosis performance in primary care

March 18, 2026

Quick Take: Intravenous patient-controlled analgesia versus thoracic epidural analgesia after open liver surgery

Lower preoperative serum calcium is associated with increased risk of postoperative complications in patients undergoing orthopedic surgery

March 11, 2026

1. Lower preoperative serum calcium levels were associated with a higher risk of postoperative complications in older orthopedic patients. Evidence Rating Level: 2 (Good) As the incidence of orthopedic diseases...

High-intensity treadmill exercise may slow progression of motor symptoms in early Parkinson’s disease

Visual perturbation training may be superior to treadmill training for reduction of fall risk in Parkinson’s disease

bySiwen Liuand1 others

March 10, 2026

1. Six weeks of visual perturbation training reduced visual dependency and improved temporal gait characteristics to a greater extent than treadmill training alone in people with early-stage Parkinson’s disease. Evidence...

Patient Basics: Shingles (Herpes Zoster)

Shingles vaccine and sildenafil linked to lower Alzheimer’s risk

byDeepti Shroff

March 10, 2026

1. An expert panel identified the shingles vaccine and sildenafil as the top candidates for repurposing to protect against Alzheimer's disease. 2. Leveraging existing drugs with established safety data could...

Glucagon-like peptide-1 receptor agonists are associated with reduced risk of developing substance use disorders

bySiwen Liuand1 others

March 9, 2026

1. Use of glucagon-like peptide-1 (GLP-1) receptor agonists was associated with reduced risk of developing substance use disorders among US veterans with type 2 diabetes. Evidence Rating Level: 2 (Good)...

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Explore the Classics Series™

ABCD2 Score: Predicting Early Stroke Risk After Transient Ischemic Attack (TIA) [Classics Series]

EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]

byMarc Succi

August 27, 2025

1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...