Tafolecimab monotherapy reduced low-density lipoprotein cholesterol by more than 60% at week 12 in phase 3 CREDIT-5 results
In topline phase 3 CREDIT-5 results, tafolecimab monotherapy reduced low-density lipoprotein cholesterol by more than 60% at week 12 versus placebo.
In At-Risk Patients With Moderate Aortic Stenosis, TAVR Reduced 2-Year Death or Heart-Failure Events
1. Treatment with transcatheter aortic-valve replacement (TAVR) showed improved outcomes at 2 years compared to a surveillance strategy in patients with moderate aortic stenosis (AS) + one at-risk feature. 2....
Nipocalimab patient interviews identify mouth dryness as the most important symptom to improve in phase 2 Sjögren’s disease data
Phase 2 patient interviews identified mouth dryness as the most important symptom to improve in Sjögren's disease, while nipocalimab increased salivary flow in exploratory analyses.
CDC reports 5,182 confirmed measles cases in the United States in 2026
The CDC reported 5,182 confirmed measles cases in the United States in 2026, with 96% associated with outbreaks.
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EAST-AFNET 4 Trial: Early Rhythm Control vs Usual Care in Atrial Fibrillation (East AF) [Classics Series]
1. The EAST-AFNET 4 trial (East AF) demonstrated that early rhythm control therapy—including antiarrhythmic drugs or catheter ablation—was associated...
BI-RADS study identifies mammography features with high positive predictive values for carcinoma [Classics Series]
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Thrombectomy between 6 and 24 hours after acute stroke reduces disability: The DAWN trial [Classics Series]
1. Thrombectomy performed between 6 and 24 hours after onset of acute stroke in patients with a mismatch between...
Ottawa ankle rules reduce the rate of referral for ankle radiography [Classics Series]
1. The Ottawa ankle rules significantly reduced referral for ankle, but not foot, radiography in the emergency department. 2....
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