All-oral chemotherapy regimen tolerable and efficacious for newly diagnosed acute myeloid leukemia
1. In this phase 1-2 trial involving patients with newly diagnosed acute myeloid leukemia who were ineligible for intensive chemotherapy,...
Thrombectomy may improve functional independence in acute ischemic stroke with medium vessel occlusion
1. In this randomized controlled trial, acute stroke patients with medium-vessel occlusion and moderate-to-severe neurological deficits who received thrombectomy in...
Ensitrelvir associated with reduced risk of Covid-19 among household contacts
1. In this randomized controlled trial, household contacts of patients with Covid-19 who received ensitrelvir shortly after exposure had reduced...
Telitacicept may reduce proteinuria in patients with high-risk IgA nephropathy
1. In this interim analysis from a randomized controlled trial, adults with biopsy-proven IgA nephropathy and persistent proteinuria who received...
Activated factor VIII-mimetic prophylaxis associated with reduced bleeding in hemophilia A
1. In adolescents and adults with hemophilia A, subcutaneous Mim8 prophylaxis reduced treated bleeding events versus on-demand therapy and versus...
![Shorter moxifloxacin-containing regimens ineffective for treating TB [REMoxTB trial]](https://www.2minutemedicine.com/wp-content/uploads/2014/09/TB-original-e1591582219420-350x250.jpg)
Near-point-of-care molecular test accurately detects pulmonary tuberculosis
1. In patients with presumptive pulmonary tuberculosis, the MiniDock MTB molecular test using sputum and tongue swabs showed diagnostic accuracy...
Nirmatrelvir–ritonavir does not improve severe outcomes in adults vaccinated against COVID-19
1. In two large randomized platform trials, early treatment with nirmatrelvir–ritonavir did not reduce hospitalization or death among mostly vaccinated,...
Triple low-dose antihypertensive pill reduced recurrent stroke after intracerebral hemorrhage
1. In clinically stable patients with prior intracerebral hemorrhage, a fixed-dose combination pill containing three low-dose antihypertensive agents reduced recurrent...
Asundexian may reduce recurrent ischemic stroke without increased bleeding risk
1. In this randomized controlled trial involving patients with recent noncardioembolic ischemic cerebrovascular accident, asundexian in combination with antiplatelet therapy...
Adjunctive prednisolone does not reduce coronary artery lesions in Kawasaki disease
1. In this randomized controlled trial involving children with newly diagnosed Kawasaki disease, adjunctive prednisolone did not reduce the incidence...
