![siRNA against antithrombin alleviates symptoms of hemophilia [PreClinical]](https://www.2minutemedicine.com/wp-content/uploads/2015/04/clot-CCWiki-350x250.jpg)
Tenecteplase not associated with visual improvement in central retinal artery occlusion
1. In this randomized controlled trial of adults with central retinal artery occlusion, tenecteplase administration shortly after symptom onset did...
Palbociclib as adjunct maintenance therapy prolongs progression-free survival in some types of metastatic breast cancer
1. This randomized controlled trial found that, in patients with hormone-receptor-positive, HER2-positive metastatic breast cancer, the addition of palbociclib to...
Sacituzumab govitecan plus pembrolizumab improves survival in advanced triple-negative breast cancer
1. Among patients with previously untreated programmed death-ligand 1 positive, triple-negative breast cancer, first-line sacituzumab govitecan plus pembrolizumab significantly prolonged...
Fremanezumab reduces migraine frequency in children and adolescents with episodic migraine
1. In this randomized controlled trial involving pediatric patients, fremanezumab led to greater reductions in the number of migraine days...
Brain-penetrant enzyme replacement therapy improves biomarkers in mucopolysaccharidosis type II
1. In this open-label phase 1–2 study, pediatric patients with mucopolysaccharidosis type II treated with tividenofusp alfa showed substantial reductions...
One dose of human papillomavirus vaccine noninferior to two for preventing persistent infection
1. In a large randomized trial of adolescent girls, one dose of either the bivalent or nonavalent human papillomavirus (HPV)...
Nucleoside-modified mRNA influenza vaccine more effective than standard shot in adults
1. A nucleoside-modified mRNA (modRNA) influenza vaccine showed greater protection against influenza-like illness compared to a standard inactivated vaccine in...
Mediterranean diet may be effective for managing IBS
1. In this randomized clinical trial, a higher percentage of adults following a Mediterranean diet achieved clinical response to irritable...
Longer bouts of exercise may be associated with decreased mortality and cardiovascular disease
1. In this prospective cohort study, cumulative all-cause mortality and risk for cardiovascular disease were lower among adults who accumulated...
Work effort and time expenditure of primary care physicians
1. In this cross-sectional study, primary care physicians were estimated to spend over sixty hours per week managing a full-time...
