1. A next-generation live-attenuated yellow fever vaccine (vYF) demonstrated noninferior immunogenicity compared to the standard vaccine, with nearly universal seroconversion...

1. In patients with resected stage III mismatch repair-deficient colon cancer, adjuvant atezolizumab plus standard chemotherapy improved disease-free survival compared...

1. In a randomized controlled trial of patients with acute venous thromboembolism, apixaban was associated with a substantially lower risk...

1. In a randomized phase 2–3 trial of patients with resectable high-risk intrahepatic cholangiocarcinoma, neoadjuvant therapy with gemcitabine–oxaliplatin, lenvatinib, and...

1. In this phase 1–2 open-label study, autologous lentiviral hematopoietic stem-cell gene therapy for cystinosis was associated with sustained engraftment...

1. In this randomized controlled trial, once-daily oral enlicitide was associated with sustained reductions in low-density lipoprotein cholesterol levels compared...

1. Among patients with previously untreated programmed death-ligand 1 positive, triple-negative breast cancer, first-line sacituzumab govitecan plus pembrolizumab significantly prolonged...

1. In this open-label phase 1–2 study, pediatric patients with mucopolysaccharidosis type II treated with tividenofusp alfa showed substantial reductions...

1. In a large randomized trial of adolescent girls, one dose of either the bivalent or nonavalent human papillomavirus (HPV)...

1. A nucleoside-modified mRNA (modRNA) influenza vaccine showed greater protection against influenza-like illness compared to a standard inactivated vaccine in...