High maternal egg-peanut intake not associated with reduced infant allergy
1. In this randomized controlled trial, high maternal consumption of eggs and peanuts during pregnancy and lactation did not reduce...
Video mental health care may have clinical advantages versus phone or in-person visits
1. In this retrospective cohort study, veterans receiving most outpatient mental health care by video had lower adjusted rates of...
Methadone initiation linked to lower mortality compared to buprenorphine-naloxone after opioid overdose
1. In this retrospective cohort study examining people who had survived a recent opioid overdose, initiating methadone was associated with...
Azacitidine–venetoclax improved event-free survival in induction-eligible AML
1. In this randomized phase 2 trial involving previously untreated adults with acute myeloid leukemia, azacitidine–venetoclax improved event-free survival compared...
Enfortumab vedotin plus pembrolizumab associated with improved survival in bladder cancer
1. In this phase 3 randomized controlled trial involving patients with muscle-invasive bladder cancer, perioperative enfortumab vedotin plus pembrolizumab significantly...
Cefazolin non-inferior to penicillins for methicillin-susceptible Staphylococcus aureus bacteremia
1. In this international randomized controlled trial of adults with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, cefazolin was noninferior to antistaphylococcal...
Nirmatrelvir–ritonavir does not improve severe outcomes in adults vaccinated against COVID-19
1. In two large randomized platform trials, early treatment with nirmatrelvir–ritonavir did not reduce hospitalization or death among mostly vaccinated,...
Asundexian may reduce recurrent ischemic stroke without increased bleeding risk
1. In this randomized controlled trial involving patients with recent noncardioembolic ischemic cerebrovascular accident, asundexian in combination with antiplatelet therapy...
Next-generation yellow fever vaccine shows comparable efficacy to standard vaccine
1. A next-generation live-attenuated yellow fever vaccine (vYF) demonstrated noninferior immunogenicity compared to the standard vaccine, with nearly universal seroconversion...
Atezolizumab may improve disease-free survival in mismatch repair deficiency locally advanced colon cancer
1. In patients with resected stage III mismatch repair-deficient colon cancer, adjuvant atezolizumab plus standard chemotherapy improved disease-free survival compared...
