Limiting antihypertensive use does not reduce mortality in nursing home residents with frailty
1. In this randomized clinical trial, among older nursing home residents with frailty who were being treated for hypertension with...
Presymptomatic treatment of spinal muscular atrophy with risdiplam leads to improved functional outcomes
1. In this single-group trial, among infants predicted to develop type 1 spinal muscular atrophy (SMA) who were treated presymptomatically...
Ciprofloxacin is non-inferior to aminoglycoside-ciprofloxacin for bubonic plague treatment
1. In this randomized controlled trial, among patients with bubonic plague, oral ciprofloxacin monotherapy was found to be noninferior to...
Trastuzumab deruxtecan leads to longer overall survival than ramucirumab plus paclitaxel in HER2-positive gastric cancer
1. In this randomized controlled trial, among adults with HER2-positive unresectable or metastatic gastric cancer who had previously progressed on...
Tirzepatide leads to greater weight loss than semaglutide among adults with obesity
1. In this randomized controlled trial, among adults with obesity, it was found that tirzepatide resulted in a significantly greater...
Tumor-infiltrating clonal hematopoiesis is associated with NSCLC recurrence
1. In this retrospective cohort study, the presence of tumor-infiltrating clonal hematopoiesis (TI-CH) was associated with an increased risk of...
Twice-yearly lenacapavir prevents HIV more effectively than daily F/TDF
1. In this randomized controlled trial, among men and gender-diverse persons who have sex with men, it was found that...
Tezepelumab alleviates symptoms in severe chronic rhinosinusitis with nasal polyps
1. In this randomized controlled trial, among patients with severe, uncontrolled chronic rhinosinusitis with nasal polyps, tezepelumab more effectively reduced...
![Oral amoxicillin as effective as injectable benzylpenicillin-gentamicin for infants with infection in which referral not possible [AFRINEST Trial]](https://www.2minutemedicine.com/wp-content/uploads/2015/04/NOVAMOXIN_antibiotic-350x250.jpg)
Seven days of antibiotic treatment non-inferior to 14 days for bloodstream infections
1. In this randomized controlled trial, among hospitalized patients with a bloodstream infection, seven days of antibiotic treatment was found...
Remibrutinib alleviates symptoms in chronic spontaneous urticaria resistant to H1-antihistamines
1. In this randomized controlled trial, among patients with chronic spontaneous urticaria who continue to have symptoms while on second-generation...
