Oncology

Reports of high-impact oncology studies by medical professionals

Sorafenib increases progression-free survival in patients with desmoid tumors

1. After 2 years of treatment with sorafenib, patients with desmoid tumors had significantly increased progression-free survival rates compared to patients randomized to a...

Quick Take: Oral Ixazomib Maintenance Following Autologous Stem Cell Transplantation (TOURMALINE-MM3): A Double-Blind, Randomised,...

Autologous stem cell transplantation (ASCT) is commonly used in the treatment of multiple myeloma, though relapse is extremely common. Ixazomib is a proteasome inhibitor...

Modified FOLFIRINOX results in longer disease-free survival in metastatic pancreatic cancer patients compared to...

1. Randomized control trial of patients with metastatic pancreatic adenocarcinoma demonstrates that adjuvant therapy with a modified FOLFIRINOX regimen results in significantly longer disease-free...

Negative colonoscopy screening linked to reduced risk of colorectal cancer and colorectal cancer-related death

1. Among average-risk adults, negative findings of a screening colonoscopy was linked to reduced risk of colorectal cancer and colorectal cancer related-deaths compared to...

Opioids unlikely to provide clinically meaningful reduction in chronic non-cancer pain

1. In this systematic review and meta-analysis of patients with chronic non-cancer pain, though opioids showed small improvements in pain, physical functioning, and sleep...

Data supports limiting blood transfusions for moderate anemia

1. The authors observed in this retrospective cohort study that transfusion rates decreased among patients from 2010 and 2014.2. Paralleling decreasing transfusion rates, the...

Quick Take: Apixaban to Prevent Venous Thromboembolism in Patients with Cancer

The risk of venous thromboembolism (VTE) is significantly increased in patients with active cancer. While parenteral prophylactic anticoagulation has been shown to reduce the...

Quick Take: Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood...

Umbilical cord blood (UCB) is a rich source of stem cells for transplantation in patients with hematologic malignancies. However, its widespread utilization has been...

Radical prostatectomy significantly improves survival in localized prostate cancer: the SPCG-4 trial

1. Among men under 75 years of age with localized prostate cancer, radical prostatectomy was associated with a significant survival benefit compared to watchful...

Increased risk for breast cancer after childbirth may last more than 20 years

1. The authors of the study concluded that parous women may have an elevated breast cancer risk for over 20 years following delivery.2. The...

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