1. In this randomized controlled trial, administering pegfilgrastim 72 hours after chemotherapy reduced bone pain compared with 24- or 48-hour...
1. Pyrotinib combined with trastuzumab and docetaxel prolonged progression-free survival compared to placebo combined with trastuzumab and docetaxel in patients...
1. Neoadjuvant capecitabine-oxaliplatin chemotherapy did not improve three-year disease-free survival compared to upfront surgery in locally advanced colon cancer. 2....
1. Neoadjuvant immunoradiotherapy with camrelizumab and radiotherapy demonstrated favourable pathologic tumour regression and safety in the management of resectable locally...
1. In a randomized phase 2–3 trial of patients with resectable high-risk intrahepatic cholangiocarcinoma, neoadjuvant therapy with gemcitabine–oxaliplatin, lenvatinib, and...
1. In this cohort study, the quadrivalent human papillomavirus (HPV) vaccine provides strong, long-lasting protection against invasive cervical cancer, with...
1. In this phase 1-2 single-group trial, the p53 reactivator rezatapopt was well-tolerated in adults with solid tumors harboring the...
1. In this prospective cohort, individuals with greater periods of sedentary time have increased risks of all-cause mortality and mortality...
1. For women at higher-than-average risk, adding supplemental MRI to DBT provided only modest additional benefit, resulting in a similar...
1. A new AI workflow utilizing large language models can predict with 99% accuracy which ulcerative colitis patients will remain...
Over the past 30 years, the transition from print to digital media has contributed to an exponential increase in medical literature. In response, 2 Minute Medicine presents 160+ authoritative, physician-written summaries of the most cited landmark trials in medicine.
