Trends in systemic lupus erythematosus pregnancy outcomes in the United States

1. In this retrospective cohort study, the authors observed that the greater decline in in-hospital maternal mortality was found for systemic lupus erythematosus (SLE)...

Opioid overdose associated with opioid prescriptions to family members

1. In this case-control study in the US, opioid overdoses were associated with history of opioid prescription to a family member, with a dose-response...

Parental, neighborhood support decrease negative impact of adverse childhood events

1. In this cross-sectional study, researchers discovered that as children’s adverse childhood events (ACEs) scores went up, their school performance and attitude declined; conversely,...

Quick Take: Effect of 1-Month Dual Antiplatelet Therapy Followed by Clopidogrel vs 12-Month Dual...

While dual antiplatelet therapy (DAPT) is the standard of care post-percutaneous coronary intervention (PCI) using drug-eluting stents (DES), the optimal duration of therapy remains...

Quick Take: Physical activity trajectories and mortality

While numerous studies have previously examined associations between physical activity and mortality, cardiovascular disease and certain cancers, the majority of this evidence has been...

Quick Take: Effect of P2Y12 Inhibitor Monotherapy vs Dual Antiplatelet Therapy on Cardiovascular Events...

The current standard therapy following percutaneous coronary intervention (PCI) with drug-eluting stents (DES) is dual antiplatelet therapy (DAPT) with aspirin plus a P2Y12 inhibitor,...

Quick Take: Investigating causal relations between sleep traits and risk of breast cancer in...

Previous studies have provided evidence for an association between circadian disruption and breast cancer risk. However, studies examining sleep traits such as chronotypes, insomnia...

Non-cardiac admissions most common for heart-failure patients in last year of life 

1. In this retrospective analysis of patients with heart failure, admissions to the hospital for non-cardiac problems were more frequent than admissions for heart...

Tanezumab provides modest benefit for osteoarthritis

1. In this randomized controlled trial, subcutaneous tanezumab resulted in moderate improvements in joint pain and physical function for patients with osteoarthritis compared to...

Quick Take: Association Between Preoperative Opioid and Benzodiazepine Prescription Patterns and Mortality After Noncardiac...

Strategies to amend clinician prescription patterns are of critical importance in addressing opioid abuse and opioid-related deaths across the United States. One potential approach...
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