#VisualAbstract: Amoxicillin for the treatment of pneumonia with tachypnea in low resource settings

1. In this noninferiority study, children who received placebo for pneumonia with tachypnea had a higher incidence of treatment failure compared to those who...

Sorafenib maintenance therapy after allogenic stem cell transplantation reduces relapse rate in FLT3-ITD acute...

1. Sorafenib maintenance therapy following allogenic stem cell transplantation in FLT3-ITD acute myeloid leukemia was associated with significantly lower rates of cancer relapse at...

Incidence trends of optic neuritis and its association with immune-mediated inflammatory diseases

1. Incidence of optic neuritis remained stable in the UK across 22 years. 2. Participants with optic neuritis demonstrated significantly greater odds of several immune-mediated...

Fifteen year quality of life outcomes in men with localized prostate cancer: population based...

1. Men diagnosed with localized prostate cancer have lower self-reported quality of life outcomes, particularly sexual function in those who underwent radical prostatectomy. 2. Mental...

Pre-hospital administration of TXA for patients at risk of hemorrhage not associated with improved...

1. In trauma patients at risk for hemorrhage, pre-hospital administration of tranexamic acid did not significantly improve 30-day mortality compared to a placebo. 2. 30-day...

Increased proportion of out of hospital cardiac arrests at start at COVID-19

1. The proportion of out of hospital cardiac arrests (OHCAs) within all acute myocardial infarction (AMI) hospital admissions was higher at the start of...

Midwifery continuity of care model not associated with improved clinical outcomes compared to standard...

1. A midwifery continuity of care model, involving maternal care before, during, and after birth, yielded no improved clinical outcomes compared to a standard...

Low dose edoxaban prevents stroke in elderly patients with atrial fibrillation

1. Low dose edoxaban was superior to placebo in preventing stroke or systemic embolism for very elderly patients with nonvalvular atrial fibrillation at risk...

#VisualAbstract: Active malignancy during COVID-19 infection not associated with increased risk of ICU admission,...

1. There was no significantly increased risk of ICU admission, intubation, or death among hospitalized patients with COVID-19 and active malignancy compared with a...

Atezolizumab may increase overall survival in patients with metastatic non-small-cell lung cancer

1. Atezolizumab significantly increased overall survival compared to platinum-based combination chemotherapy in participants with untreated metastatic non-small-cell lung cancer (NSCLC) and high programmed death...
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