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Long-acting cabotegravir significantly decreases incidence of HIV compared to daily oral tenofovir
1. Cabotegravir was shown to be superior to TDF-FTC in preventing HIV infection in women. 2. Both drugs were well...
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Oral methylprednisolone may reduce risk of progressive renal failure in patients with IgA nephropathy: TESTING Trial
1. This randomized controlled trial found that high dose methylprednisolone for 6-9 months reduced rates of significantly declining kidney function,...
Imiquimod noninferior to surgery in management of vulvar high-grade squamous intraepithelial lesions
1. Complete clinical response at 6 months was similar in both the topical imiquimod and surgery group. 2. Invasive disease...
Endovascular abdominal aortic aneurysm repair may be associated with higher overall mortality and complications compared to open repair
1. In this retrospective cohort study, endovascular aneurysm repair was associated with significantly higher rates of long-term rupture and reintervention...
Meditation may provide medical benefit for various health outcomes
1. Meditative therapies appear to be more beneficial for improving sleep quality, fatigue management and depressive symptoms, especially in patients...
Awake prone positioning does not seem to offer benefit in reducing endotracheal intubation for COVID-19-induced acute respiratory failure: COVI-PRONE trial
1. This randomized clinical trial demonstrated no difference in the risk of endotracheal intubation requirement at 30 days between awake...
The antibody drug conjugate MRGOO3 is a promising for use in EGFR-expressing cancers
1. The median progression free survival for all cancer-types was 2.8 months. 2. Most of the adverse events (AEs) were...
Associations remain inconclusive between religiosity and spirituality on medication adherence in cardiovascular disease
1. There was a significant association (positive or negative depending on demographic factors) between religiosity and spirituality (R/S) and medication...
Vaccination boosted immunity acquired from previous SARS-CoV-2 infection
1. Two doses of the Pfizer-BioNTech BNT162b2 vaccine were linked to high immediate protection again severe acute respiratory syndrome coronary...
Single-dose Ad26.COV2.S vaccine provides moderate protection against Covid-19 related outcomes
1. One dose of Ad26.COV2.S (Johnson & Johnson) provided some protection against moderate to severe Covid-19-related infection and medical intervention....
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