Idiopathic inflammatory myositis linked to statin exposure
1. In this case control study from Australia, patients with histologically confirmed idiopathic inflammatory myositis (IIM) were more likely to report exposure to statin...
Hospital admission linked to reduced quality and quantity of sleep
1. For patients admitted to hospital, the reported quantity and quality of sleep was reported to be worse compared to habitual at home sleep...
Pre-hospital plasma transfusion in patients at risk of hemorrhagic shock decreases mortality
1. In patients at risk of hemorrhagic shock, the pre-hospital administration of thawed plasma decreased mortality at 24 hours and 30 days and patients...
Fewer adverse myocardial events in depressed patients treated with antidepressants after acute coronary syndrome
1. In this prospective cohort study, depressed patients with Acute Coronary Syndrome (ACS) who were treated with escitalopram were less likely to have Major...
Early in-bed cycling and electrical stimulation no different than standard rehabilitation for global muscle...
1. There was no difference in muscle strength at discharge between intensive care unit (ICU) patients who underwent in-bed cycling and electrical stimulation compared...
Patisiran is effective in treatment of hereditary transthyretin amyloidosis.
1. Patisiran, an RNA interference agent, improved neuropathy symptoms and motor function in patients with hereditary transthyretin amyloidosis after 18 months of use.
2. Types...
Hospital admission linked to reduced quality and quantity of sleep
1. For patients admitted to hospital, the reported quantity and quality of sleep was reported to be worse compared to habitual at home sleep...
Paradigm shift in cancer treatment to targeted therapies
1. HER2 targeted breast cancer treatment has significantly improved prognosis.
2. Novel immune checkpoint therapies have resulted in considerable clinical response for a variety...
Comparative analysis of wounds from oral mucosa versus skin reveals novel therapeutic targets for...
1. Comparative profiling of wounds induced in the oral mucosa versus skin revealed expression of genes that prime the oral mucosa for wound healing....
Viral vector based gene therapies show promise for treating focal epilepsy [PreClinical]
1. Seizures are often associated with accumulation of extracellular glutamate due to the synchronous discharges of excitatory neurons.
2. Treatment of rats with a lentiviral...
