Clinician denial of certain patient requests linked with decreased satisfaction

1. In an observational study of a single family practice clinic, clinician-patient interactions in which a request was denied was linked to lower patient...

Multiple treatment trajectories exist in adolescent depression

1. In this longitudinal retrospective cohort study, there were multiple treatment trajectories identified among youth with depression. 2. Psychotherapy monotherapy was associated with the lowest...

Parents report greater optimism than oncologists about their child’s cancer prognosis

1. Three quarters of parents of children with a cancer diagnosis report greater optimism about their child’s prognosis than the child’s physician. 2. Parents who...

Non-alcoholic fatty liver disease associated with brain volume loss in middle-aged individuals

1. In this cross-sectional study of middle-aged adults, radiologic evidence of non-alcoholic fatty liver disease (NAFLD) was associated with reduced total cerebral brain volume...

Erenumab linked to decreased episodic migraine frequency: The STRIVE trial

1. Monthly injections of erenumab were associated with reduced migraine frequency, decreased use of acute migraine medication, and decreased migraine burden on daily activities...

Fremanezumab reduces headache frequency in patients with chronic migraine

1. Patients with chronic migraine receiving fremanezumab had significantly fewer migraines and headaches than those receiving placebo after 12 weeks of treatment. 2. Injection-site reactions,...

Extremely premature children have worse cognitive outcomes

1. Extremely premature (EP) and extremely low birth weight (ELBW) infants born in the early 2000s have worse executive function outcomes when compared to...

Surgeons from Massachusetts General Hospital Express Support for Research on Firearm Violence 

1. Pediatric surgeons from Massachusetts General Hospital promote research funding to address the current public health crisis of gun violence in a special commentary published in...

Evidence-based supportive therapy for bronchiolitis varies significantly between hospitals

1. Less than 75% of study infants hospitalized with acute bronchiolitis received the current recommended treatment, evidence-based supportive therapies (EBST), with significant variation between...

Tezacaftor-ivacaftor improves pulmonary function in cystic fibrosis patients: The EVOLVE trial

1. Tezacaftor-Ivacaftor significantly improves lung function and reduces the frequency of pulmonary exacerbations in cystic fibrosis (CF) patients homozygous for the Phe508 deletion (Phe508del). 2....
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