Insulin management in hospitalized patients with diabetes mellitus on high-dose glucocorticoids

1. Using a 50% basal (glargine) and 50% bolus (lispro) insulin therapy, glucocorticoid (GC) exacerbated hyperglycemic patients were associated with higher capillary blood glucose (CBG)...

Active monitoring compared to maintenance capecitabine is a viable alternative for stable metastatic colorectal...

1. Progression-free survival was extended by the use capecitabine as compared to active monitoring, but at the expense of increased toxicity. There was no...

Gemcitabine with ramucirumab improved overall survival for malignant pleural mesothelioma

1. Compared to the gemcitabine with placebo group, the gemcitabine with ramucirumab group had longer overall survival as a potential second-line treatment for malignant...

Sleep quality during pregnancy may help predict emotional distress in postpartum period

1. In this study, first time mothers with longer sleep time during pregnancy were less likely to report high levels of anxiety and depression...

Inadequate health literacy in nulliparous individuals is associated with worse maternal and neonatal outcomes

1. 17.5% of individuals giving birth for the first time were found to have inadequate health literacy. 2. Individuals with inadequate health literacy were at...

Unexplained syncope and orthostatic hypotension linked to increased risk of subsequent fractures.

1. In a large cohort of patients hospitalized due to unexplained syncope and orthostatic hypotension, there was an increased risk of subsequent fractures in...

Mental health in young adults may be linked to sleep chronotype

1. Young adults with evening chronotypes recorded higher depression and anxiety scores, and poorer sleep quality in comparison to morning and intermediate chronotypes. 2. Positive...

Camrelizumab with chemotherapy demonstrated improved overall survival and progression-free survival of esophageal squamous cell...

1. Camrelizumab improved the overall survival and the progression-free survival of esophageal squamous cell carcinoma patients compared to placebo treatment as adjuvants to chemotherapy. 2....

Detection of pathogenic genetic variants in early-onset atrial fibrillation

1. Genetic testing in patients with early-onset atrial fibrillation, via major commercial arrhythmia and cardiomyopathy gene panels, were able to detect a disease-associated variant...

Heterologous ChAdOx1 prime-boosted vaccination schedules are non-inferior to homologous vaccination

1. Heterologous AstraZeneca followed by Pfizer vaccination was noninferior to homologous, two-dose AstraZeneca vaccination with a geometric mean ratio of 9.2. 2. Heterologous Pfizer followed...

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