Inhaled inorganic nitrites do not improve exercise capacity in heart failure with preserved ejection...

1. In this randomized controlled trial, there was no difference in mean peak oxygen consumption between patients with Heart Failure with preserved Ejection Fraction...

Zoliflodacin (ETX0914) effectively treats urogenital gonorrhea

1. Patients with uncomplicated urogenital gonorrhea treated with the novel antibiotic zoliflodacin, developed in part due to increasingly antibiotic resistant gonorrhea, were cured at...

The TARGET: Energy density of enteral nutrition not associated with mortality

1. Patients undergoing mechanical ventilation randomized to receive energy-dense enteral nutrition experienced similar rates of mortality at 90-days compared to patients treated with routine...

Quick Take: Association of Weather With Day-to-Day Incidence of Myocardial Infarction: A SWEDEHEART Nationwide...

The influence of certain weather trends on the incidence of myocardial infarction (MI) has not been well established. In this prospective population-based study, investigators...

Organic food consumption linked to reduced cancer risk

1. Self-reported consumption of labeled organic foods in a French population was linked to lower rates of cancer development in this prospective cohort study.  Evidence...

Quick Take: Association of Secondary Preventive Cardiovascular Treatment After Myocardial Infarction With Mortality Among...

Patients with schizophrenia have a shortened life expectancy of 15-20 years compared with the general population, with excess cardiac mortality contributing to this difference....

Quick Take: Phase Ib/II Study of Pembrolizumab and Pegylated Interferon Alfa-2b in Advanced Melanoma

Programmed death-1 (PD-1) inhibitors have shown efficacy in the treatment of melanoma. Pre-existing CD8+ T-cell infiltrate and interferon (IFN) gene signature has been shown...

E-cigarette users have greater odds of subsequent cigarette use

1. Among adolescent never smokers, electronic cigarette (e-cigarette) users had approximately 4-fold greater odds of initiating cigarette use at follow-up 2-3 years later. 2. Frequency...

Quick Take: Intravenous Iron in Patients Undergoing Maintenance Hemodialysis

Patients undergoing hemodialysis typically receive intravenous iron, despite a lack of established clinical efficacy. In this randomized controlled trial, investigators randomized 2141 patients undergoing...

Treatment of hypertension in low-risk patients not linked with improved outcomes

1. In this retrospective cohort study of low-risk patients with mild hypertension, treatment of hypertension was not linked to any change in mortality or...

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