Quick Take: Continuous Subcutaneous Insulin Infusion Versus Multiple Daily Injection Regimens in Children and...

Multiple daily injections (MDI) and continuous subcutaneous insulin infusion (CSII) are two forms of intensive insulin regimens utilized by patients with type 1 diabetes....

HCV-positive heart and lung transplant likely safe with post-transplant sofosbuvir-velatasivir treatment

1. HCV-naive patients in need of heart or lung transplants who received organs from HCV-positive donors and were treated with sofobuvir-velpatasvir demonstrated intact graft...

Quick Take: Effect of a Multifaceted Quality Improvement Intervention on the Prescription of Evidence-Based...

In low and middle-income countries, the implementation of evidence-based therapies for cardiovascular disease, including the use of statins, antiplatelet therapy and anti-hypertensive medications, remains...

Quick Take: Pembrolizumab Versus Chemotherapy for Previously Untreated, PD-L1-Expressing, Locally Advanced or Metastatic Non-Small-Cell...

Pembrolizumab is a monoclonal antibody against programmed cell death protein 1 (PD-1). Previous studies have shown that pembrolizumab is effective in prolonging survival in...

Pre-exposure HIV prophylaxis may lead to riskier behavior and increased STIs

1. In this population intervention study, receipt of HIV preexposure prophylaxis (PrEP) was associated with an increased incidence of STIs in homosexual and bisexual...

Electronic health record clinical and genomic data provides relevant insights for non-small cell lung...

1. In patients with non-small cell lung cancer (NSCLC), an analysis of clinical and genomic data from routine care replicated previously established relationships between...

Exclusive breastfeeding linked to slight decrease in adolescent LDL Cholesterol

1. Exclusive breastfeeding in the first 3 months of life, as opposed to mixed breast and bottle feeding and exclusive bottle feeding, was associated...

Catheter-based renal denervation reduces blood pressure in patients with uncontrolled hypertension

1. Meta-analysis of sham-controlled randomized trials of catheter-based renal denervation demonstrated reduction in ambulatory and office systolic blood pressures.2. Second-generation trials demonstrated greater reduction...

Quick Take: Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g

Little is known about the survival and neurodevelopmental outcomes of extremely preterm infants with low birth weight. More data is needed to facilitate decisions...

Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the...

Intravenous thrombolytic therapy with alteplase (recombinant human tissue plasminogen activator) is approved for the treatment of acute ischemic stroke. However, whether it is efficacious...
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