Quick Take: Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN)

Tenosynovial giant cell tumor (TGCT) is a rare mesenchymal neoplasm that arises in the joints, bursae, or tendon sheaths. The standard treatment is surgical...

Effective adolescent mental health programs incorporate interpersonal skills, emotional regulation, and drug education

1. Of 25 psychosocial intervention components studied in adolescents, only interpersonal skills, emotional regulation, and alcohol and drug education predicted positive effects across multiple...

Quick Take: Comparison of Outcomes After Transcatheter vs Surgical Aortic Valve Replacement Among Patients...

In patients who have previously undergone coronary artery bypass graft surgery (CABG), surgical aortic valve replacement (SAVR) can be a complicated procedure due to...

Quick Take: Treatment Outcomes of Immune-Related Cutaneous Adverse Events

Immune-checkpoint inhibitors (ICIs) have significantly improved outcomes in a variety of malignancies. Immune-related adverse events, however, are common and may lead to treatment discontinuation...

Quick Take: Safety and Efficacy of the Addition of Lapatinib to Perioperative Chemotherapy for...

Current international guidelines recommend a combination of perioperative chemotherapy and surgery in the treatment of operable gastroesophageal cancer. However, given high mortality rates in...

The MR-INFORM trial: fewer patients undergo revascularization when coronary perfusion is assessed with MRI...

1. In patients with stable angina and multiple cardiac risk factors, those undergoing myocardial-perfusion cardiovascular magnetic resonance imaging (MRI) compared to invasive angiography and...

Defining airflow obstruction as FEV1:FVC of less than 0.70 optimal compared to other fixed...

1. In this retrospective cohort study, an FEV1:FVC threshold of 0.71 was the best fit for discriminating COPD-related events, though it was not statistically...

Quick Take: Suicide in older adults living in or transitioning to residential long-term care,...

It is estimated that by the year 2050, 1 in 5 individuals will be 65 years or older. In addition to the growing number...

Social robots increase joy, decrease sadness in hospitalized pediatric patients

1. In this randomized control trial, researchers discovered that social robots were associated with improved affect in pediatric hospitalized patients as compared to plush...

Beneficiaries of Medicare Advantage run higher risk of readmission compared with traditional Medicare

1. In this retrospective cohort study, the authors observed that Medicare Advantage beneficiaries have a higher risk of readmission compared to traditional Medicare in...
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