Behavioral dysregulation in infancy predicts later child mental health

1. Infants classified as having moderately or severely unsettled behavioral regulation at 12 months of age had greater odds of having a positive behavioral...

De novo design of artificial IL-2 mimic for the treatment of cancer [PreClinical]

1. IL-2 is a central cytokine that enhances the immune response, with considerable potential for the treatment of cancer.2. A mimic of IL-2 binds...

Quick Take: Hospital admission on weekends for patients who have surgery and 30-day mortality...

Previous work has suggested that healthcare interventions on weekends may be associated with increased mortality, but findings have been inconsistent. In this matched cohort...

The POET trial: oral antibiotics in stable endocarditis patients noninferior to intravenous treatment

1. Patients with left sided infective endocarditis who switched to oral antibiotics once stable had similar composite adverse event outcomes compared to patients treated...

Automated office blood pressure measurement more accurate than routine office readings

1. In this systematic review and meta-analysis, routine office systolic blood pressure readings were, on average, higher than automated office blood pressure readings.2. Awake...

Individualized exercise program linked to faster recovery following pediatric sport-related concussion

1. In this randomized control trial of pediatric sport-related concussion (SRC), a progressive sub-symptom threshold aerobic exercise program was linked to a shorter time...

EEG-guided anesthetic administration unlikely to reduce post-operative delirium

1. In this randomized controlled trial, EEG-guided anesthetic administration during surgical interventions did not reduce the incidence of delirium compared to anesthetic administration as...

Type 1 diabetes unlikely to affect standardized test performance

1. In this Danish retrospective cohort study, there was no association between standardized reading and mathematics test scores and type 1 diabetes.2. Among those...

Topical creams likely ineffective in treating localized chronic pain

1. In a randomized controlled trial, researchers found that topical analgesic creams were ineffective in treating localized chronic pain.2. Compared to the placebo, there...

Antibiotic therapy for asthma exacerbation associated with longer hospital stay

1. In this retrospective cohort study looking at patients admitted with asthma exacerbations and treated with corticosteroids, antibiotic administration within the first two days,...

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