On-demand sildenafil (Viagra) shows limited effectiveness for Raynaud phenomenon

1. Sildenafil may be more effective than placebo for treating patients with Raynaud phenomenon. 2. Patient responses to sildenafil treatment showed substantial heterogeneity. Evidence Rating...

Gastric bypass most effective for weight loss among common bariatric procedures

1. Roux-en-Y gastric bypass was found to be the most effective bariatric procedure reviewed in this study in terms of patient weight loss. 2. The...

American College of Physicians updates policy recommendations for reducing gun-related injuries and deaths in...

1. The American College of Physicians (ACP) revises and expands on current policy recommendations regarding gun-related injuries and deaths. 2. The evidence for policy changes...

Public underestimates the relative frequency of firearm-related violent deaths

1. In this study, only a few adults correctly identified the most frequent cause of firearm-related violent deaths. 2. A higher number of firearm-related suicides...

Medical vaccine exemptions increase after elimination of nonmedical exemptions

1. After California eliminated nonmedical exemptions from school-entry vaccinations in 2015, the proportion of kindergarten students who received all required vaccines rose from 92.8%...

Quick Take: Efficacy and cost-effectiveness of nurse-led care involving education and engagement of patients...

Gout is the most common inflammatory-type arthritis worldwide, resulting from the presence of intra-articular sodium urate crystals. In addition to painful gout attacks, resulting...

Quick Take: Pre-eclampsia and risk of dementia later in life: nationwide cohort study

Pre-eclampsia is defined as new onset hypertension accompanied by signs of organ dysfunction in the setting of pregnancy. Unfortunately, the risks associated with pre-eclampsia...

Quick Take: The IRIS Trial: Effect of cricoid pressure compared with a sham procedure...

The administration of anesthetic agents during induction results in a loss of protective upper airway reflexes, and thus may be associated with an increased...

Quick Take: β-Blocker use in pregnancy and the risk of congenital malformations: an international...

Beta-blocker medications are commonly used in managing high blood pressure in pregnancy. With an increased prevalence of obesity and related comorbidities in women of...

Quick Take: Use of radiography in patients diagnosed as having acute bronchiolitis in US...

Bronchiolitis occurs with the viral infection of the lower respiratory tract, carrying with it a significant health burden among young children. According to the...

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