Neurology

Reports of high-impact neurology studies by medical professionals

The SPICE III trial: dexmedetomidine is rarely effective as a sole agent for sedation...

1. Patients in the intensive care unit (ICU) randomized to continue sedation for ventilation with dexmedetomidine often required use of supplementary propofol, midazolam, or...

Quick Take: Robot assisted training for the upper limb after stroke (RATULS)

Upper limb functionality is often compromised after a stroke, leading to distressing long-term consequences and a diminished quality of life. Therefore, optimizing upper limb...

Quick Take: Amyotrophic Lateral Sclerosis versus Multifocal Motor Neuropathy: Utility of MR Neurography

Both multifocal motor neuropathy (MMN) and amyotrophic lateral sclerosis (ALS) affect the peripheral nervous system and present with palsies. Differentiating between these two diseases...

Quick Take: Association of Blood and Cerebrospinal Fluid Tau Level and Other Biomarkers With...

Human prion disease, also known as Creutzfeldt-Jakob disease (CJD), is a neurodegenerative disease caused by abnormally folded prion proteins. The progression of CJD is...

Use of aspirin for primary prevention linked to increased risk of intracranial hemorrhage

1. In this systematic review and meta-analysis, use of low-dose aspirin in patients without symptomatic cardiovascular disease was linked with an increased risk of...

PET scans show high tau levels in former NFL players with potential chronic traumatic...

1. Former National Football League (NFL) players with cognitive and neurological symptoms showed higher tau amyloid levels as detected on positron emission tomography (PET)...

The EXTEND trial: neurological deficits decreased with thrombolysis up to 9 hours after stroke...

1. Patients presenting between 4.5 and 9 hours after stroke onset with viable brain tissue who received thrombolytic therapy had better neurological outcomes compared...

Quick Take: Association of socioeconomic status and brain injury with neurodevelopmental outcomes of very...

Preterm birth remains a leading cause of lifelong neurodevelopmental disability. While the effect of brain injury on neurodevelopmental disability has been studied extensively, far...

Trans-nasal cooling during cardiac arrest does not improve survival with good neurologic outcome

1. In this randomized controlled trial, intra-cardiac arrest, trans-nasal evaporative cooling did not improve survival with good neurologic outcome at 90 days compared to...

Quick Take: Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer...

Alzheimer disease (AD) is characterized by the accumulation of amyloid b (Ab) and tau aggregates in the brain. The progression of AD can be...
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