Neurology

Reports of high-impact neurology studies by medical professionals

Non-drug interventions highly efficacious at reducing depressive symptoms in people with dementia

1. Systematic review found that social prescribing was associated with a reduction in depressive symptoms in patients with dementia without a diagnosis of major...

Young adult patients recovering from COVID-19 might be at increased risk of acute ischemic...

1. The rate of acute ischemic stroke was elevated in South Asian males recovering from asymptomatic SARS-CoV-2 2019 (COVID-19) infection. Evidence Rating Level: 4 (Below...

Levetiracetam not clinically effective nor cost-effective compared to valproate for newly diagnosed generalized or...

1. 12-month remission was superior with valproate than with levetiracetam. 2. Compared to levetiracetam, patients in the valproate group reported fewer adverse reactions (42% vs....

Lamotrigine offers higher net health benefits and is more cost-effective than levetiracetam and zonisamide...

1. Lamotrigine offered greater clinical benefit, fewer adverse reactions, and higher cost-utility normalized to quality-adjusted life years compared to levetiracetam and zonisamide. 2. Lamotrigine continues...

Immunovirotherapy showed acceptable adverse-event profile in pediatric high-grade gliomas

1. Treatment with herpes simplex virus type 1 oncolytic virotherapy was shown not to demonstrate serious adverse events in pediatric patients with high-grade gliomas. 2....

Effect of high-frequency spinal cord stimulation in patients with painful diabetic neuropathy

1. Pain relief and health-related quality of life was significantly improved among those undergoing 10-kHz spinal cord stimulation, compared to conventional medical management. 2. Outcomes...

Direct oral anticoagulants more effective in patients with valvular atrial fibrillation

1. Patients who received a direct oral anticoagulant had a lower risk of thromboembolic events and major bleeds compared to patients who received warfarin. 2....

Sex and race‐ethnic disparities in door‐to‐CT time in acute ischemic stroke found in Florida...

1. Women patients with stroke were 10% less likely than male patients to achieve a door-to-computed tomography time (DTCT) within 25 minutes, the recommended...

Spinal cord stimulation shows considerable improvement in pain and quality of life for patients...

1. 10-kHz spinal cord stimulation (SCS) was safe and effective in treating patients with painful diabetic neuropathy (PDN) refractory to medical management, leading to...

Ponesimod may be superior to teriflunomide for relapsing multiple scleorsis

1. Ponesimod was superior to teriflunomide for relapsing multiple sclerosis, in terms of reducing relapse rates, unique active lesions on MRI, and fatigue symptoms. Evidence...

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