Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Heterologous ChAdOx1 prime-boosted vaccination schedules are non-inferior to homologous vaccination

1. Heterologous AstraZeneca followed by Pfizer vaccination was noninferior to homologous, two-dose AstraZeneca vaccination with a geometric mean ratio of 9.2. 2. Heterologous Pfizer followed...

Inhaled budesonide shortens time to recovery for high-risk COVID-19 patients in the community

1. Time to recovery was lower in patients assigned to budesonide compared to usual care, meeting the superiority criteria. 2. Rate of hospitalizations or death...

Association of age and pediatric household transmission of SARS-CoV-2 infection

1. Children aged 0 to 3 years old were more likely than children aged 14 to 17 to transmit SARS-CoV-2 to other household members. Evidence...

Milrinone and dobutamine show no difference for cardiogenic shock treatment

1. Milrinone was shown not to be significantly different than dobutamine for the treatment of cardiogenic shock. 2. In-hospital deaths of patients treated with either...

Metformin does not improve the progression-free survival of stage IIIA or IIIB locally advanced...

1. Metformin, in addition to standard chemoradiation therapy, did not improve the progression-free survival, overall survival, local-regional recurrence, or distant metastasis occurrence compared to...

Canakinumab not associated with increased survival without invasive mechanical ventilation among patients hospitalized with...

1. Among patients hospitalized with severe COVID-19 and hyperinflammation, treatment using the anti-interleukin-1β antibody canakinumab, compared with placebo, did not significantly increase the likelihood...

Study highlights trends and outcomes of bronchodilator use in infants with bronchiolitis

1. In a large retrospective study, the rate of bronchodilator use during emergency visits for infants with bronchiolitis decreased from 51.5% to 22.8% between...

Seroprevalence of SARS-CoV-2 differed among different types of healthcare workers in Italy in the...

1. Health care assistants and nurses were at the highest risk of contracting SARS-CoV-2 among healthcare professionals early in the COVID-19 pandemic in Italy. 2....

Systematic analysis of tobacco smoking prevalence in 204 countries from 1990 to 2019

1. In 2019, 1.14 billion individuals worldwide were active smokers, accounting for 7.41 trillion cigarette-equivalents of tobacco. 2. Without intervention, the current count of 7.69...

Standard cytisine treatment for smoking cessation does not demonstrate noninferiority compared to standard varenicline...

1. Among adult daily smokers attempting to quit, cytisine treatment over 25 days failed to demonstrate noninferiority regarding smoking cessation when compared with standard...

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