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Duloxetine is effective in refractory chronic cough
1. Duloxetine is significantly more effective than placebo at reducing refractory chronic cough (RCC) frequency and sensitivity. Evidence Rating Level:...
Pulmonology
Reports of high-impact pulmonology studies by medical professionals
One in three people with cystic fibrosis may experience nephrolithiasis during their life
1. Nearly one in three people with cystic fibrosis experienced nephrolithiasis during their lifetime. 2. The degree of exocrine pancreatic...
Middle-aged and older Canadians at high risk of obstructive sleep apnea may have worse mental health outcomes
1. Middle-aged and older Canadian adults at high risk of obstructive sleep apnea (OSA) had worse mental health outcomes than...
Etomidate is associated with higher in-hospital mortality compared with ketamine in rapid sequence intubation for severely ill patients
1. Etomidate is associated with significantly higher in-hospital 7- and 28-day mortality compared with ketamine in rapid sequence intubation (RSI)...
Positive lung cancer screens frequently receive suboptimal follow-up
1. In this retrospective cohort study, most patients with a positive lung cancer screening result received guideline-concordant follow-up, though nearly...
Adjunct corticosteroids likely reduce short-term mortality in severe non-COVID-19 pneumonia
1. In this systematic review and meta-analysis, adjunct corticosteroids likely reduce short-term mortality in patients with severe non-COVID-19 pneumonia and...
Age-based screening for lung cancer may be more cost-effective and improve detection compared to current screening criteria in the United States
1. Current US Preventive Services Task Force (USPSTF) screening criteria for lung cancer excludes many at-risk individuals and has poor...
Men with idiopathic pulmonary fibrosis have increased mortality compared with women
1. Men with idiopathic pulmonary fibrosis (IPF) have a higher comorbidity burden, worse baseline lung function, and shorter survival, with...
Influenza vaccination improves survival and reduces readmissions in patients hospitalized for acute heart failure
1. All-cause mortality and hospital readmissions were significantly decreased with influenza vaccination compared to usual care. 2. Significantly fewer adverse...
Dupilumab use is associated with lower all-cause mortality but increased risk of lymphoma in asthma patients
1. When compared with inhaled corticosteroids (ICS) plus long-acting β-agonists (LABA), dupilumab treatment was associated with an increased risk of...
