Pulmonology

Reports of high-impact pulmonology studies by medical professionals

Defining airflow obstruction as FEV1:FVC of less than 0.70 optimal compared to other fixed...

1. In this retrospective cohort study, an FEV1:FVC threshold of 0.71 was the best fit for discriminating COPD-related events, though it was not statistically...

Beneficiaries of Medicare Advantage run higher risk of readmission compared with traditional Medicare

1. In this retrospective cohort study, the authors observed that Medicare Advantage beneficiaries have a higher risk of readmission compared to traditional Medicare in...

Bacteremia in pediatric pneumonia associated with disease severity

1. In this retrospective analysis of prospectively collected data, researchers found that pediatric patients with pneumonia and bacteremia were more likely to have serious...

Quick Take: Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs...

Protective intraoperative mechanical ventilation has been associated with reduced postoperative pulmonary complication risk. Obesity is associated with an increased risk of atelectasis and impaired...

Quick Take: Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With...

Venous thromboembolism (VTE) is a common complication in patients with cancer. Often, VTEs are incidentally detected on imaging studies undertaken for cancer staging or...

The SPICE III trial: dexmedetomidine is rarely effective as a sole agent for sedation...

1. Patients in the intensive care unit (ICU) randomized to continue sedation for ventilation with dexmedetomidine often required use of supplementary propofol, midazolam, or...

The SENSCIS trial: nintedanib slows declines in FVC in patients with interstitial lung disease...

1. The SENSCIS trial, a randomized control trial studying the efficacy of nintedanib, an intracellular tyrosine kinase inhibitor, versus placebo on respiratory function among...

Benralizumab not shown to ameliorate COPD exacerbation rates when compared to placebo

1. Two complementary phase 3 clinical trials randomized patients with moderate-to-severe COPD to receive either benralizumab or a placebo and found that the trial...

Quick Take: Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP)

Corticosteroids are frequently used in the treatment of acute chronic obstructive pulmonary disease (COPD) exacerbations. However, the use of systemic corticosteroids is not without...

Unrecognized obstructive sleep apnea increases risk of postoperative cardiovascular events

1. In this prospective cohort study, severe but not moderate, unrecognized obstructive sleep apnea was associated with increased postoperative cardiovascular events in patients undergoing...
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