Quick Take: Prophylactic Irradiation of Tracts in Patients With Malignant Pleural Mesothelioma: An Open-Label,...
Malignant pleural mesothelioma is a devastating cancer, with survival rates ranging from as low as 17% to 46%. Diagnosis and/or treatment usually involves an...
In utero administration of ivacaftor averts multiorgan disease in ferret model of cystic fibrosis...
1. A G551D missense mutation in the cystic fibrosis transmembrane conductance receptor (CFTR) is a genetic cause of cystic fibrosis (CF).2. In utero administration...
Shorter treatment regimen found to be noninferior for patients with multidrug resistant tuberculosis
1. A randomized control trial of patients with multidrug resistant tuberculosis found that shorter treatment regimens were noninferior to longer treatment regimens currently recommended...
The PreVent trial: bag-mask ventilation decreases hypoxia in patients undergoing tracheal intubation
1. For intensive care unit (ICU) patients undergoing tracheal intubation, bag-mask ventilation between induction and laryngoscopy resulted in less hypoxia during the procedure.2. No...
Omadacycline is noninferior to moxifloxacin in treating community acquired bacterial pneumonia
1. Intensive care unit (ICU) hospitalized adults with community acquired bacterial pneumonia had comparable clinical responses when taking antibiotic courses of omadacycline, a new...
Antibiotic therapy for asthma exacerbation associated with longer hospital stay
1. In this retrospective cohort study looking at patients admitted with asthma exacerbations and treated with corticosteroids, antibiotic administration within the first two days,...
Hydrocortisone in very preterm infants does not improve rates of bronchopulmonary dysplasia and mortality
1. There were no significant differences in rates of bronchopulmonary dysplasia (BPD) and mortality at 36 weeks’ postmenstrual age (PMA) as a composite outcome...
Quick Take: Use of Hormone Replacement Therapy and Risk of Venous Thromboembolism: Nested Case-Control...
Hormone replacement therapy (HRT), often prescribed to women during menopause, has been shown to increase the risk for venous thromboembolism (VTE). However, the effects...
Hospital Readmissions Reduction Program associated with increased 30-day post-discharge mortality for heart failure and...
1. In this retrospective cohort study, implementation of the Hospital Readmissions Reduction Program (HRRP) was unexpectedly associated with an increase in 30-day post-discharge mortality...
Quick Take: Apixaban to Prevent Venous Thromboembolism in Patients with Cancer
The risk of venous thromboembolism (VTE) is significantly increased in patients with active cancer. While parenteral prophylactic anticoagulation has been shown to reduce the...
