Coronary CT-angiography-guided management improves outcomes in patients with stable chest pain
1. Composite of coronary heart disease death and non-fatal myocardial infarction was less frequent in the CCTA group compared to...
Pulmonology
Reports of high-impact pulmonology studies by medical professionals
Depemokimab therapy reduces exacerbations in patients with severe eosinophilic asthma
1. In this randomized, placebo-controlled replicate trial, depemokimab decreased the annual rate of exacerbations among patients with severe eosinophilic asthma....
High flow nasal cannula reduces hypoxia for obese patients undergoing endoscopy
1. The use of high flow nasal cannula (HFNC) in patients with obesity undergoing sedated gastrointestinal endoscopy significantly reduced the...
Increased blood–urea–nitrogen-to-albumin ratio associated with increased mortality in coronavirus disease
Association between blood–urea–nitrogen-to-albumin ratio and in-hospital mortality in patients diagnosed with coronavirus disease 2019: a retrospective cohort study 1. Increased...
Different single inhaler triple therapies appear to have similar clinical outcomes for chronic obstructive pulmonary disease
1. In a cohort of adults with chronic obstructive pulmonary disease (COPD), receiving fluticasone-umeclidinium-vilanterol was not associated with improved clinical...
Fractional dosing of pneumococcal conjugate vaccine noninferior to full dosing schedule
1. In this randomized non-inferiority trial, 40% of a full dose of the 13-valent pneumococcal conjugate vaccine (PCV13) was noninferior...
Reduced pneumococcal vaccine schedules non-inferior to WHO recommendations
1. In this cluster-randomized controlled trial, it was found that a pneumococcal conjugate vaccine (PCV) schedule involving a single primary...
RAMOSE Phase II trial finds promising results for osimertinib and ramucirumab in non-small cell lung cancer
1. Treatment of patients with tyrosine kinase inhibitor (TKI)-naïve epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) with...
Point of care C-reactive protein testing may be useful in guiding antibiotic prescribing
1. C-reactive protein (CRP)-point-of-care tests can be used to guide antibiotic prescribing in primary care for patients with acute exacerbations...
Amivantumab plus lazertinib improves survival in EGFR-mutated advanced NSCLC
1. In this randomized trial, amivantamab-lazertinib led to significantly longer progression-free survival than osimertinib therapy for mutated advanced non-small-cell lung...
