Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Quick Take: Glucagon Receptor Antagonist–Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age

Glucagon-containing α-cells are important for regulating glucose homeostasis along with insulin-secreting β-cells. Glucagon receptor antagonists (GRAs) hold potential as antidiabetic therapies, but there is...

Ticagrelor reversal agent provides immediate and sustained effect

1. A monoclonal antibody fragment to ticagrelor, PB2452, increased platelet function significantly in healthy patients given the oral P2Y12 inhibitor ticagrelor.2. Adverse effects were...

Single dose aspirin prior to fecal immunochemical testing does not increase detection of advanced...

1. In this randomized controlled trial, single dose aspirin given two days prior to fecal immunochemical testing (FIT) did not increase test sensitivity for...

Quick Take: Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and...

Laparoscopic cholecystectomy for the treatment of symptomatic cholecystolithiasis is currently the standard of care. However, multiple studies indicate that 10-41% of patients continue to...

Quick Take: Individualised nutritional support in medical inpatients at nutritional risk

Malnutrition is a common occurrence in hospitalized patients. Current clinical practice guidelines recommend considering placing medical inpatients deemed to be at risk of malnutrition...

Nutrients from food, not supplements, linked to lower risks of death, cancer

1. This prospective cohort study suggested that nutrients derived from food were associated with lower risks of all-cause death among participants.2. Excess calcium intake...

Quick Take: Safety and Feasibility of Using Magnetic Resonance Imaging Criteria to Identify Patients...

For patients with rectal cancer, the strongest predictor of local recurrence is the circumferential resection margin (CRM) after surgery, with negative CRMs being the...

Quick Take: Association of Domestic Responsibilities With Career Satisfaction for Physician Mothers in Procedural...

Although females currently account for roughly 50% of graduates from U.S. medical schools, there is a skew in terms of which residencies or medical...

Quick Take: The burden of health conditions for middle-aged and older adults in the...

Understanding the burden of health conditions in older adults in the U.S. is essential in addressing the healthcare demands of this patient population. This...

Internal medicine interns spending minority of time on direct inpatient care

1. In this direct observational study, first year internal medicine residents (interns) spent only 13% of their time on direct patient care, while spending...
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