Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Quick Take: Ultra-processed food intake and risk of cardiovascular disease

The consumption of ultra-processed food has increased substantially over the last several decades. These foods often have higher proportions of total and saturated fat,...

Quick Take: Estimates of all cause mortality and cause specific mortality associated with proton...

Proton pump inhibitors (PPIs) are widely used in the management of gastroesophageal reflux. However, several studies have demonstrated serious adverse events associated with PPI...

Quick Take: Low rates of specialized cancer consultation and cancer-directed therapy for noncurable pancreatic...

Eighty percent of patients with advanced or metastatic pancreatic adenocarcinoma are not candidates for surgical resection and require noncurative therapy, including multi-agent chemotherapy regimens,...

Quick Take: Treatment and Long-Term Clinical Outcomes of Incidental Pulmonary Embolism in Patients With...

Venous thromboembolism (VTE) is a common complication in patients with cancer. Often, VTEs are incidentally detected on imaging studies undertaken for cancer staging or...

Laparoscopic distal gastrectomy non-inferior to open distal gastrectomy for locally advanced gastric cancer

1. In this randomized clinical trial, three-year disease-free survival rates were similar for patients with locally advanced gastric cancer treated with laparoscopic vs. open...

Quick Take: Liver Fibrosis and Metabolic Alterations in Adults with Alpha1 Antitrypsin Deficiency Caused...

Alpha-1 antitrypsin (AAT) is a major protease inhibitor responsible for the inhibition of neutrophil elastase and proteinase 3. Alpha-1 antitrypsin deficiency (AATD) is a...

Quick Take: Fracture risk after Roux-en-Y gastric bypass adjustable gastric banding among Medicare beneficiaries

Roux-en-Y gastric bypass (RYGB) is associated with significant bone loss and may increase fracture risk as a result. This is in contrast to other...

Quick Take: Body composition and cardiovascular events in patients with colorectal cancer

Patients with colorectal cancer (CRC) are 2-4 times more likely to develop cardiovascular disease, as compared to individuals without a history of cancer. With...

Quick Take: Glucagon Receptor Antagonist–Stimulated α-Cell Proliferation Is Severely Restricted With Advanced Age

Glucagon-containing α-cells are important for regulating glucose homeostasis along with insulin-secreting β-cells. Glucagon receptor antagonists (GRAs) hold potential as antidiabetic therapies, but there is...

Ticagrelor reversal agent provides immediate and sustained effect

1. A monoclonal antibody fragment to ticagrelor, PB2452, increased platelet function significantly in healthy patients given the oral P2Y12 inhibitor ticagrelor.2. Adverse effects were...
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