Gastroenterology

Reports of high-impact gastroenterology studies by medical professionals

Modified FOLFIRINOX results in longer disease-free survival in metastatic pancreatic cancer patients compared to...

1. Randomized control trial of patients with metastatic pancreatic adenocarcinoma demonstrates that adjuvant therapy with a modified FOLFIRINOX regimen results in significantly longer disease-free...

Negative colonoscopy screening linked to reduced risk of colorectal cancer and colorectal cancer-related death

1. Among average-risk adults, negative findings of a screening colonoscopy was linked to reduced risk of colorectal cancer and colorectal cancer related-deaths compared to...

Biosimilar to infliximab shows equivalent safety and efficacy for treating Crohn’s disease

1. The biosimilar to infliximab, CT-P13 was shown in this study to have equivalent efficacy to the anti tumor-necrosis factor (TNF) monoclonal antibody for...

Proton pump inhibitor co-therapy reduces gastrointestinal bleeding risk of oral anticoagulants

1. In this retrospective cohort study, rivaroxaban had the highest and apixaban had the lowest upper gastrointestinal bleeding (UGIB) risk.2. Proton Pump Inhibitor (PPI)...

Quick Take: Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis

The use of probiotics has been suggested as a way to improve outcomes in children with gastroenteritis. In this randomized controlled trial, investigators randomized...

The TARGET: Energy density of enteral nutrition not associated with mortality

1. Patients undergoing mechanical ventilation randomized to receive energy-dense enteral nutrition experienced similar rates of mortality at 90-days compared to patients treated with routine...

Gastric bypass most effective for weight loss among common bariatric procedures

1. Roux-en-Y gastric bypass was found to be the most effective bariatric procedure reviewed in this study in terms of patient weight loss.2. The...

Quick Take: Effect of lorcaserin on prevention and remission of type 2 diabetes in...

There is a strong relationship between body weight and the risk of developing diabetes. Lorcaserin is a selective serotonin 2C receptor agonist that suppresses...

Lorcaserin does not increase rate of cardiovascular events in overweight or obese patients

1. At a median follow-up of 3.3 years, rates of composite cardiovascular events in at-risk overweight or obese patients treated with lorcaserin were not...

Tailoring fecal immunochemical tests positivity thresholds by age and sex may help to optimize...

1. Cancer detection among participants was higher with lower positivity thresholds.2. Sensitivity with conventional fecal immunochemical tests (FIT) thresholds decreased with increasing age and...
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