Association between atrial fibrillation and both the in-hospital mortality and disease severity in acute pancreatitis: insights from a multicenter study

1. Among patients with acute pancreatitis (AP), a history of atrial fibrillation (AF) was associated with increased disease severity but not in-hospital mortality. 

Evidence Rating Level: 2 (Good)

AP is a condition associated with significant mortality with a rising global incidence in recent years. AF is a cardiac arrhythmia disorder associated with an increased risk of thromboembolic events and substantial disability. While both conditions are associated with significant mortality, there is a lack of research investigating the association between AP and AF. This retrospective cohort study therefore sought to investigate the association between AF and in-hospital mortality with AP in a population of Chinese patients. 3537 patients from 3 Chinese medical centres with a diagnosis of AP were included in this study, among whom 122 patients (3.45%) had a history of AF. A history of AF was not independently associated with increased in-hospital mortality (OR: 1.65, 95% 124 CI: 0.68-3.68; Hosmer and Lemeshow test P value > 0.1). However, a history of AF was independently associated with increased disease severity (OR: 1.65, 95% CI: 1.11-2.44; Hosmer and Lemeshow 127 test P value > 0.1). Overall, this study found that among Chinese patients with AP, a history of AF was associated with increased disease severity but not in-hospital mortality.

Click here to read this study in BMC Gastroenterology

Image: PD

©2025 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.