Tag: cardiology

1. Among patients with HFpEF and resistant hypertension, administration of spironolactone was associated with a reduced risk of composite cardiovascular events, all-cause mortality, and hospitalization for heart failure. Evidence Level Rating: 2 (Good) Heart failure with preserved ejection fraction (HFpEF) and resistant hypertension, a salt-retaining condition secondary to inappropriate aldosterone secretion,...
1. Children with congenital heart disease experience seasonal peaks (late spring and autumn) and dips (winter and summer school holidays) in physical activity. Evidence Rating Level: 1 (Excellent) Occurring in 1 of 100 live births, congenital heart disease (CHD) is the most common congenital defect in newborns. WIth survival rates increasing...
1. Non-calcium-based phosphate binders did not affect arterial stiffness or aortic calcification compared to placebo in moderate-to-severe chronic kidney disease. Evidence Rating Level: 1 (Excellent) Abnormal phosphate homeostasis is characteristic of chronic kidney disease, with hyperphosphatemia strongly associated with increased arterial stiffness secondary to calcification. Positive phosphate balance may contribute to...
Association between antipsychotic use and acute ischemic heart disease in women but not in men: a retrospective cohort study of over one million primary care patients 1. There was a moderate association found between antipsychotic use and acute ischemic heart disease found in women, but not men. Evidence Rating Level: 2...
1. Low BMI, Killip class 3/4, history of previous MI, use of mechanical support, and flow worsening were shown to be significantly associated with major adverse cardiac events (MACE) in patients with an ST-elevation myocardial infarction (STEMI) who have achieved a door-to-balloon time (DTBT) under 90 minutes. 2. Radial access...
1. Among patients who have received a saphenous vein graft during coronary bypass surgery and later experience treatment failure, deployment of a drug-eluting stent during percutaneous coronary intervention leads to more favorable outcomes than does use of a bare-metal stent. Evidence Rating Level: 1 (Excellent) Study Rundown: Though it has been...
1. A total of 7 medium- and long-chain acylcarnitines were associated with higher risk of atrial fibrillation (AF). 2. Caffeine and acisoga were associated with increased risk of incident AF while beta carotene was associated with a lower risk. Evidence Rating Level: 2 (Good) Atrial fibrillation (AF) is the most common cardiac...
1. Among patients who have received a saphenous vein graft during coronary bypass surgery and later experience treatment failure, deployment of a drug-eluting stent during percutaneous coronary intervention leads to more favorable outcomes than does use of a bare-metal stent. Evidence Rating Level: 1 (Excellent) Study Rundown: Though it has been...
The Incidence, Risk Factors and In-Hospital Mortality of Acute Kidney Injury in Patients After Surgery for Acute Type A Aortic Dissection: A Single-Center Retrospective Analysis of 335 Patients 1. For patients undergoing surgical interventions for acute type A aortic dissections (AAAD), post-operative acute kidney injury was shown to increase patient...
1. Higher amounts of weekly physical exercise were associated with better carotid-to-femoral pulse wave velocities but not with carotid distensibility, which are both markers of arterial stiffness. 2. Diabetic patients may benefit from a more profound correlation between physical exercise with carotid-to-femoral pulse wave velocity. Evidence Rating Level: 2 (Good) Arterial stiffness...