Tag: cardiology

1. 12-months after randomization, the de-escalation group met the criteria for superiority (p=0.0001) with respect to the composite primary outcome of cardiovascular mortality, myocardial infarction, stroke, or bleeding. 2. Type 2, 3, or 5 bleeding was significantly less frequent in the clopidogrel group (3.0%) compared to ticagrelor group (5.6%). Evidence Rating...

1. In a large cohort of patients with intermittent claudication, smoking prior to open and endovascular revascularization was associated with increased post-procedural complications. Evidence Rating Level: 2 (Good) Treatment guidelines for intermittent claudication (IC) recommend optimal medical therapy, which includes smoking cessation, prior to considering revascularization. However, most patients are not...

1. In a cohort of laypersons participating in Basic Life Support courses, video-based and simulation-based teaching methods led to improved recognition of breathing patterns compared to standard teaching. Evidence Rating Level: 1 (Excellent) Agonal breath sounds are present in about half of the victims during early cardiac arrest. However, teaching laypersons...

The effect of adiposity on cardiovascular function and myocardial fibrosis in patients with Duchenne muscular dystrophy 1. In a cohort of patients with Duchenne muscular dystrophy, adiposity was associated with cardiac dysfunction. Evidence Rating Level: 2 (Good) Duchenne muscular dystrophy (DMD) is an X-linked recessive disease that leads to the absence of...

1. In the pre-COVID-19 analysis, hemodynamic monitoring reduced hospitalization and all-cause mortality rates. 2. After the COVID-19 pandemic started, hospitalization of heart failure patients was reduced and there were no appreciable differences between the control and hemodynamic monitoring group. Evidence Rating Level: 1 (Excellent) Study Rundown: Worsening hemodynamic congestion is a major...

Comparison of Routine With Clinically Indicated Replacement of Peripheral Intravenous Catheters 1. Routine replacement of peripheral intravenous catheters (PVCs) every 96 hours was associated with fewer PVC-associated bloodstream infections (PVC-BSIs) compared to PVC replacement only when clinically indicated. Evidence Rating Level: 2 (Good) Nearly 60% of patients in hospital undergo an insertion of a...

1. In a large cohort of patients hospitalized due to unexplained syncope and orthostatic hypotension, there was an increased risk of subsequent fractures in the future. Evidence Rating Level: 2 (Good) Study Rundown: The overlap between syncope, orthostatic hypotension, and falls is being increasingly studied in research. Falls, especially in...

1. The risk of developing atrial fibrillation was significantly greater in athletes compared to non-athletes. 2. Younger (<55 yrs) and mixed sport athletes had a greater risk of developing atrial fibrillation than older athletes and those participating in endurance sports respectively. Evidence Rating Level: 1 (Excellent) Many studies have shown that exercise...

1. In this large cohort study, women had a significantly higher risk of in-hospital adverse events after undergoing a percutaneous left atrial appendage occlusion when compared to men. Evidence Rating Level: 2 (Good) Atrial fibrillation is the most common sustained arrythmia and it is associated with significant morbidity and mortality, including...