Tag: cardiology

1. In a large cohort of hospitalized patients in Maryland, it was found that Black patients with aortic stenosis had a lower incidence of surgical treatment when compared to their White counterparts. Evidence Rating Level: 2 (Good) Aortic stenosis is one of the most common valvular heart diseases which is...

The trial to reduce antimicrobial use in nursing home residents with Alzheimer disease and other dementias (TRAIN-AD) 1. In a large trial, a multi-component interventional program did not reduce antimicrobial use amongst people with advanced dementia living in nursing homes. Evidence Rating Level: 1 (Excellent) Antimicrobials are commonly prescribed to individuals within...

1. Clopidogrel monotherapy reduced long-term rates of all-cause mortality, non-fatal myocardial infarction, and stroke after drug-eluting stent placement compared with aspirin monotherapy. 2. The superiority of clopidogrel was seen for both thrombotic and bleeding endpoints and was consistent across demographic groups. Evidence Rating Level: 1 (Excellent)  Study Rundown: Patients who receive percutaneous...

1. Compared to placebo, patients treated with mavacamten for 30 weeks showed significant improvements on the KCC Questionnaire which evaluates health status and quality of life. 2. In patients with symptomatic hypertrophic cardiomyopathy, the number needed to treat with mavacamten was 5. Evidence Rating Level: 2 (Good) Study Rundown: The EXPLORER-HCM...

1. There was no significant difference found in thrombosis or bleeding outcomes for patients with atrial fibrillation or mechanical heart valves, where patients were randomly assigned to receive dalteparin or a placebo after an invasive procedure requiring cessation of warfarin. Evidence Rating Level: 1 (Excellent) Patients with atrial fibrillation or mechanical...

1. A nationwide Swedish study demonstrated that patients with congenital heart disease are at an increased risk of developing ischemic stroke compared to controls. Evidence Rating Level: 3 (Average) Congenital heart disease (CHD) is the most common major congenital anomaly, and it is associated with an increased risk of complications...

1. A prospective observational study demonstrated moderate agreement between clinicians and researchers in assigning patients a HEART score. Evidence Rating Level: 2 (Good) The HEART score is a risk stratification aid used frequently in emergency departments (ED) to estimate the probability of major adverse cardiac events within 30 days for...

Burden of ischemic stroke in patients with congenital heart disease: A nationwide, case‐control study 1. A nationwide Swedish study demonstrated that patients with congenital heart disease are at an increased risk of developing ischemic stroke compared to controls. Evidence Rating Level: 3 (Average) Congenital heart disease (CHD) is the most common...

1. In patients with recent ischemic stroke and no diagnosed atrial fibrillation (AF), there were increased AF diagnoses in those who received an implantable loop recorder compared with those who received an external loop recorder within 12 months of the intervention. Evidence Rating Level: 1 (Excellent) Study Rundown: Atrial fibrillation (AF)...

Short-Term Antibody Response After 1 Dose of BNT162b2 Vaccine in Patients Receiving Hemodialysis 1. A single dose of BNT162b2 vaccine did not elicit a humoral immune response in most people receiving hemodialysis who had no history of previous SARS-CoV-2 infection. Evidence Rating Level: 2 (Good) One of the several groups of people...