Tag: cardiology
ACEi and ARB use not associated with increased risk of COVID-19 hospitalization or mortality
Kathleen Lau -0
1. There is no association between ACE inhibitor or ARB use compared with other antihypertensives for risk of COVID-19 hospitalization for outpatients.
2. There is no association between ACE inhibitor or ARB use compared with other antihypertensives for increased mortality risk in patients hospitalized with diagnosis of COVID-19.
Evidence...
Diagnosis and treatment of iron deficiency in heart failure: OFICSel study by the French Heart Failure Working Group
1. Cardiologists were under-testing, against guidelines, for iron deficiency in heart failure patients, likely resulting in under-diagnosing and under-treatment.
Evidence Rating Level: 2 (Good)
One in every two patients with heart failure (HF) also...
Lower risk of dementia in patients with atrial fibrillation taking non-vitamin K antagonist oral anticoagulants: A nationwide population-based cohort study
1. Among patients with incident atrial fibrillation, the use of non-vitamin K antagonist oral anticoagulants compared with warfarin was associated with a decreased risk of dementia.
Evidence Rating Level: 2 (Good)
While...
Poor cardiovascular health associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations
Jack Lennon -
1. The American Heart Association’s cardiovascular health index has clinical utility with an understudied sub-Saharan African population.
2. The targets for preventing atherosclerosis in this population are smoking, obesity, hypertension, hyperglycemia, and physical activity.
Evidence Rating Level: 3 (Average)
The American Heart Association’s cardiovascular health index (CVHI) is known to be a...
Liver fibrosis in post-PCI patients associated with higher incidence of cardiovascular events
Kathleen Lau -
1. Post-PCI patients with intermediate to high liver fibrosis scores were observed to experience higher incidences of major cardiovascular events.
Evidence Rating Level: 1 (Excellent)
While the introduction of percutaneous coronary interventions (PCI) have significantly reduced the rate of major cardiovascular events in patients with coronary artery disease, patients post-PCI continue...
Alcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation
Kathleen Lau -
1. Low to moderate alcohol intake was not significantly associated with risk of stroke or other cardiovascular outcomes in patients with atrial fibrillation.
Evidence Rating Level: 2 (Good)
“Holiday heart syndrome” describes the association found between excessive alcohol intake and incidence of atrial arrhythmias. Even low amounts of regular alcohol intake...
#VisualAbstract: Paclitaxel coating of endovascular devices not associated with a difference in all-cause mortality
Constance Wu -
1. Patients with peripheral artery disease who received a drug-coated device did not face an increased risk of death compared to those who received an uncoated device at any point during the 2+ year follow-up.
2. This finding appeared to be independent of disease severity, although the wide confidence interval...
Independent and Synergistic Effects of High Blood Pressure and Obesity on Retinal Vasculature in Young Children: The Hong Kong Children Eye Study
1. Hypertension and overweight to obese BMI in children were associated with changes in retinal microvasculature.
Evidence Rating Level: 2 (Good)
Hypertension and obesity, two of the most important risk...
Machine learning-based PRAISE score may aid in the prediction of adverse events following an acute coronary syndrome
Neel Mistry -
1. The PRAISE score showed accurate discriminative capabilities for the prediction of all-cause death, acute myocardial infarction, and major bleeding after an acute coronary syndrome.
2. Compared with low risk stratification, a high-risk PRAISE score was associated with a 58.8-times increase in death, 27.7-times increase in myocardial infarction, and a...
Gaps in evidence-based therapy use in patients with type 2 diabetes mellitus and atherosclerotic cardiovascular disease
Jack Lennon -
1. Significant gaps were found in the use of evidence-based therapies in insured patients with atherosclerotic cardiovascular disease and type 2 diabetes mellitus.
Evidence Rating Level: 2 (Good)
Prevalence of atherosclerotic cardiovascular disease (ASCVD) in patients with type 2 diabetes mellitus (T2DM) is twice as high as those without T2DM, resulting...