Tag: cardiology

1. Inflammatory bowel disease (IBD) is associated with increased risk of coronary microvascular dysfunction (CMD). 2. Surgical intestinal resection in IBD patients improved coronary flow velocity reserve (CFVR), a measure of CMD. Evidence Rating Level: 2 (Good) Inflammatory bowel diseases (IBDs) include conditions such as Crohn Disease (CD) and Ulcerative Colitis (UC)....
1. In this cross-sectional study, women with premature atherosclerotic cardiovascular disease (ASCVD) and extremely premature ASCVD were less likely to receive antiplatelet agents or statins than men. Evidence level rating: 2 (Good) Secondary prevention guidelines highlight the importance of initiation antiplatelet and statin therapy in patients with ASCVD, especially...
1. In patients treated with direct oral anticoagulants (DOACs) for atrial fibrillation or venous thromboembolism (VTE), adding aspirin (ASA) was associated with increased bleeding events. 2. Adding ASA to DOAC treatment for patients with atrial fibrillation or VTE did not improve the incidence of thrombotic events. Evidence Rating Level: 2 (Good) Study Rundown: Aspirin...
1. Hypertension, diabetes, smoking, atrial fibrillation, and previous myocardial infarction were associated with a higher risk of incident heart failure in younger adults (<55 years) compared to elderly participants (≥75 years). 2. There were no interactions between age and body-mass index or glomerular filtration rate with respect to the incidence...
1. Pre-term birth was associated with significantly increased risk of adult-onset heart failure, particularly among those 18 to 43 years of age. Evidence Rating Level: 2 (Good) Preterm birth is a known risk factor for early-life heart failure (HF). However, less is known about its association with adult-onset HF. This Swedish...
1. Bioelectric impedance analysis-measured edema index (EI) is a feasible, non-invasive technique for measuring fluid overload. 2. EI is an independent predictor of cardiorespiratory fitness in heart failure patients with reduced ejection fraction and type 2 diabetes mellitus. Evidence Rating Level: 2 (Good) One of the prominent features of heart failure (HF)...
1. 30% of the population suffers from reflex syncope, a major cause of transient loss of consciousness. Understanding genetic basis of this condition may offer new insight on therapeutic solution. Evidence Rating Level: 2 (Good) Study Rundown: Previously, population-based studies on familial aggregation of reflex syncope were lacking. This cohort study...
1. Direct oral anticoagulants may have a superior risk-benefit profile compared to vitamin K antagonists in atrial fibrillation for patients with hemodialysis. Evidence Rating Level: 2 (Good) While direct oral anticoagulants (DOACs) have been shown to have superior risk-benefit profiles over vitamin K antagonists (VKAs) in patients with atrial fibrillation and...
1. Patients who had schizophrenia, bipolar disorder or major depression had worse short-term mortality outcomes at 30 days and 1 year and were less likely to receive coronary revascularization. Evidence Rating Level: 2 (Good) For patients with severe mental illness (SMI, includes schizophrenia (SCZ), bipolar disorder (BPD) and major depression (MD)),...
1. In both obese and non-obese patients, NT-proBNP level <1000pg/mL during treatment showed favourable prognostic implications in heart failure with reduced ejection fraction. Evidence Rating Level: 2 (Good) While obesity itself is a major risk factor for developing heart failure, overweight and obese patients have been reported to have paradoxically better...