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✦EvidencePulse™by 2 Minute Medicine3 reportsYou askedtop stroke trials 2026Synthesizing medical evidence...Top 2026 stroke trial results:OCEANIC — ischemic stroke: 6.2% vs 8.4%OPTION* — mRS 0–1: 43.6% vs 34.2%ORIENTAL* — mRS 0–2: 58.6% vs 46.6%*Higher sICH in intervention armsParticipants randomizedNOCEANIC12,327OPTION570ORIENTAL564Ask about guidelines or landmark trials...↑Try EvidencePulse™Ask the evidence. Get the signal.Try it now →
Home All Specialties Cardiology

Acceptance and commitment therapy not associated with different outcomes in patients with coronary artery disease

byPaary Balakumar, MD, MScandAlex Chan
June 20, 2024
in Cardiology, Chronic Disease, Psychiatry
Reading Time: 2 mins read
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1. Acceptance and Commitment Therapy in patients with coronary heart disease does not affect short-term biological indicators of risk but does improve psychological well-being timelines

Evidence Rating Level: 1 (Excellent)

This randomized controlled trial aimed to evaluate the efficacy of Acceptance and Commitment Therapy (ACT) on biological and psychological well-being of patients with coronary heart disease. The control group received the usual care (UC) of a 6-week multidisciplinary outpatient cardiac rehabilitation program which includes physical exercise, educational counselling, and medical exams. The experimental group received the same care with the addition of ACT given as 3 group sessions. Over the course of care, participants were tested for low-density lipoproteins (LDL), resting systolic blood pressure, body mass index, and a psychological well-being score (Psychological General Well-Being Index – PGWBI). Additionally, psychological inflexibility, dietary habits, exercise, smoking status and quality of life were assessed using questionnaires. Of the tested measures, the only significant change seen was a time effect seen in PGWBI. The study would have been improved with a larger sample size (n=92) though the heterogeneity in the population due to broad inclusion criteria means the results are more generalizable. Conducting the study with the UC as a control group is also a strength as other studies tend to compare to no treatment. A longer ACT duration should be done to investigate the effect of ACT length on outcomes.

Click to read the study in the BMJ (British Medical Journal)

Image: PD

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