Tag: psychiatry

1. Individuals with bipolar disorder at higher risk of chronic kidney disease after lithium initiation include patients who are young, female, obese, have high LDL cholesterol, and have lower baseline eGFR levels. Evidence Rating Level: 2 (Good) Lithium is the standard first-line treatment for bipolar disorder worldwide. However, due to its...

1. Mood disorder diagnoses prior to hospitalization for COVID-19 was associated with increased risk of in-hospital mortality after Day 12. 2. Prior mood disorders were associated with a greater likelihood of discharge to a lower level of care, rather than home. Evidence Rating Level: 2 (Good) Extrapulmonary manifestations of COVID-19 have been...

Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy 1. Pain relief and health-related quality of life was significantly improved among those undergoing 10-kHz spinal cord stimulation, compared to conventional medical management. 2. Outcomes in pain relief were sustained through the six-month follow-up. Evidence Rating Level: 1 (Excellent) The...

1. Older adults with recent diagnoses of mild cognitive impairment (MCI) or dementia were significantly more likely to attempt suicide, compared to those without these diagnoses. Evidence Rating Level: 2 (Good) Study Rundown: The relationship between cognitive decline and suicide is unclear, with most studies focusing on dementia and specific suicidal...

1. Patients who had schizophrenia, bipolar disorder or major depression had worse short-term mortality outcomes at 30 days and 1 year and were less likely to receive coronary revascularization. Evidence Rating Level: 2 (Good) For patients with severe mental illness (SMI, includes schizophrenia (SCZ), bipolar disorder (BPD) and major depression (MD)),...

P2Y12 inhibitor monotherapy after coronary stenting according to type of P2Y12 inhibitor 1. In patients undergoing percutaneous coronary intervention, 3-month dual antiplatelet therapy (DAPT) followed by P2Y12 inhibitor monotherapy showed comparable cardiovascular outcomes to 12-month DAPT. Evidence Rating Level: 2 (Good) Several randomized trials have showed that after percutaneous coronary intervention (PCI),...

1. Among adolescents with treatment-resistant depression, an infusion of ketamine significantly reduced depressive symptoms over a two-week period compared with an infusion of midazolam. Evidence Rating Level: 2 (Good) Study Rundown: Major depressive disorder (MDD) has a lifetime prevalence of nearly 20% by adolescence and is associated with substantial morbidity and...

1. Telephone cognitive behavioral therapy for insomnia (CBT-I) was an effective treatment for sleep issues among patients with osteoarthritis pain (OA). 2. Fatigue was significantly reduced among the CBT-I group, compared to the education-only group. 3. CBT-I demonstrated evidence of short-term pain reduction, but this was not sustained at 12-month follow-up. Evidence...

1. High adiponectin and low leptin levels were associated with greater anxiety and depression symptoms in postmenopausal women. Evidence Rating Level: 2 (Good) Rates of depression and anxiety are nearly 2 times higher during and after menopause, with some prevalence estimates ranging from 18-41.8% and 7-25% for peri- and postmenopausal periods...

1. Schizophrenia spectrum disorders were significantly associated with mortality among adults with COVID-19. 2. Participants with Schizophrenia had 2.7 times the odds of death due to COVID-19 than those without Schizophrenia. 3. Mood and anxiety disorders were not associated with COVID-19-related mortality. Evidence Rating Level: 2 (Good) Study Rundown: Coronavirus disease 2019 (COVID-19)...