Poloxamer 188 not effective for acute management of vaso-occlusive episodes in patients with sickle...

1. Poloxamer 188 did not decrease parenteral opioids reliance for pain control during acute vaso-occlusive episodes in adults and children with sickle cell disease. Evidence...

Aspirin treatment without indication in patients on direct oral anticoagulants may increase the risk...

1. In patients treated with direct oral anticoagulants (DOACs) for atrial fibrillation or venous thromboembolism (VTE), adding aspirin (ASA) was associated with increased bleeding...

Postoperative infection post-fracture linked to substantially reduced future household income

1. Postoperative infection in patients with surgically treated fractures is associated with significantly decreased patient household income Evidence Rating Level: 2 (Good) Study Rundown: Approximately 6.3...

Targeted intervention improved infant bronchiolitis treatment by deimplementing ineffective management practices

1. Targeting specific ineffective bronchiolitis treatment practices and further educating hospital staff on appropriate treatment was more effective at deimplementing inappropriate treatment, compared to...

Time-limited trials may decrease the length of stay of critically ill patients in the...

1. Time-limited trial interventions in patients with poor prognoses decreased length of stay in ICU, reduced minimally beneficial treatments, and increased communication between clinicians...

Sex and race‐ethnic disparities in door‐to‐CT time in acute ischemic stroke found in Florida...

1. Women patients with stroke were 10% less likely than male patients to achieve a door-to-computed tomography time (DTCT) within 25 minutes, the recommended...

ST-elevation myocardial infarctions in the absence of standard modifiable cardiovascular risk factors may have...

1. Patients without standard modifiable cardiovascular risk factors (SMuRFs) had a significantly higher all-cause mortality at 30 days after first presentation of STEMI. 2. Patients...

Reflex syncope might be associated with familial relationship degree

1. 30% of the population suffers from reflex syncope, a major cause of transient loss of consciousness. Understanding genetic basis of this condition may...

4PEPS clinical probability score may reduce need for imaging in suspected pulmonary embolism

1. The 4PEPs strategy (4-Level Pulmonary Embolism Clinical Probability Score) may be a useful tool for emergency department physicians in patients suspected of pulmonary...

Non-consensus transient ischemic attacks linked to high short-term and long-term risks of stroke  

1. Risk of recurrent stroke within 90 days of an index event was comparable among patients with non-consensus TIA and classic TIA. 2. Patients with...

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