Radial-artery grafts outperform saphenous-vein grafts when used in CABG: The RADIAL trial

1. Patients undergoing coronary artery bypass grafting (CABG) who received a radial-artery graft rather than a saphenous-vein graft (both groups also received an internal-thoracic-artery...

Viruses not linked to asthma exacerbation severity

1. Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure. Evidence Rating Level: 2 (Good) Study Rundown: Viral...

MRI pattern selects patients with unknown stroke time who benefit from thrombolysis

1. Stroke patients with unknown time of stroke onset and DWI-FLAIR mismatch indicative of a stroke within the prior 4.5 hours who were randomized...

ECMO for severe ARDS does not improve mortality

1. Extracorporeal membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) did not show a 60-day mortality benefit compared to conventional ventilation and...

Aldosterone antagonist therapy linked to reduced mortality following STEMI without heart failure

1. In this meta-analysis of available randomized clinical trials, use of aldosterone antagonist therapy in patients with preserved ejection fraction following ST-elevation myocardial infarction...

Physicians should look for misuse patterns that lead to overdose before prescribing opioids

1. All opioid misuse patterns examined had a positive association with opioid overdose and death. 2. High number of prescribers and/or pharmacies was a key...

Physicians report feeling moral distress over hospital policies that force inadequate care based on...

1. Physicians working in settings that provide emergency only hemodialysis (EOHD) reported higher rates of professional burnout. 2. Physicians providing EOHD reported feeling moral distress...

Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial

1. In patients with mild asthma, use of the inhaled combined corticosteroid (ICS) and beta agonist budesonide-formoterol as needed was superior to terbutaline as...

AAP recommends life support training for general public

1. The Committee on Pediatric Emergency Medicine of the American Academy of Pediatrics (AAP) has published a statement in support of bystander CPR and AED...

Long-acting buprenorphine depot injections may be efficacious in treatment of opioid use disorder

1. In this double-blind randomized controlled trial, weekly or monthly buprenorphine depot injections were non-inferior to daily sublingual buprenorphine/naloxone in maintaining no evidence of...
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