Obstetrics

Reports of high-impact obstetrics and gynecology studies by medical professionals

The NAMSAL ANRS 12313 trial: HIV viral suppression similar for dolutegravir and low-dose efavirenz...

1. For previously untreated HIV-1 patients in Cameroon, treatment with dolutegravir was noninferior to low dose efavirenz at lowering viral load over a period...

Quick Take: Pregnancy duration and endometrial cancer risk

Full-term pregnancies are strongly associated with a reduced risk of endometrial cancer. Whether this protective association is driven by fecundity, a specific process that...

Quick Take: T-Cell Receptor Gene Therapy for Human Papillomavirus–Associated Epithelial Cancers: A First-in-Human, Phase...

Genetically engineered T-cell therapies, such as chimeric antigen receptor T-cells (CAR T-cells), have been approved for the treatment of hematologic malignancies, however, there are...

Quick Take: Association between maternal pre-pregnancy obesity and preterm birth according to maternal age...

Preterm birth is the leading cause of infant mortality and neonatal morbidity. Maternal obesity is associated with an increased risk of gestational diabetes and...

Quick Take: Assessment of long-term distant recurrence-free survival associated with tamoxifen therapy in post-menopausal...

Most estrogen receptor (ER)-positive breast cancers can be classified as luminal A or luminal B subtype. It has been estimated that 1 in 4...

Quick Take: Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES)

Studies have shown that intrahepatic cholestasis of pregnancy is associated with poor birth outcomes and neonatal unit admission. Ursodeoxycholic acid, which increases bile acid...

Quick Take: Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe...

Hypertension commonly affects women in pregnancy, and is associated with adverse effects for both mother and baby. Currently, there is a lack of consensus...

Racial, ethnic differences in outcomes of extremely preterm infants decreasing but persistent

1. In this retrospective cohort study reviewing data from 2006 to 2017, researchers showed very premature infants identified as African American had more rapid...

Quick Take: Overall survival with ribociclib plus endocrine therapy in breast cancer

Hormone therapy is the standard of care for premenopausal and postmenopausal women with hormone receptor-positive, human epidermal growth factor receptor2 (HER2)-negative advanced breast cancer....

Challenges and feasibility of fertility preservation in feminizing transgender youth

1. In this retrospective cohort study, fertility preservation proved feasible in transgender feminizing youth, both before and after the initiation of gender-affirming hormonal therapies.2....
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