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Lilly’s retatrutide achieves significant weight loss and A1C reduction in Phase 3 trial
1. Retatrutide met all major Phase 3 endpoints, delivering substantial reductions in both A1C and body weight in patients with...
Pharma
Zorevunersen appears safe and may alleviate symptoms in children with Dravet syndrome
1. In this phase 1/2a trial involving patients with Dravet syndrome who received intrathecal zorevunersen, treatment-related adverse events occurred in...
Apixaban (eliquis) outperforms Rivaroxaban (xarelto) in venous thromboembolism bleeding risk
1. In the randomized COBRRA trial, apixaban was associated with substantially less clinically relevant bleeding than rivaroxaban in patients with...
Pfizer’s Talzenna combo significantly delays prostate cancer progression
1. The combination of talazoparib and enzalutamide demonstrated a statistically significant improvement in radiographic progression-free survival for metastatic hormone-sensitive prostate...
Ketorolac administration after cesarean delivery may reduce postoperative opioid use
1. In this randomized controlled trial, a 60‑mg IV ketorolac loading dose after cesarean delivery modestly reduced postoperative opioid use...
2 Minute Medicine: Pharma Roundup – Pfizer’s Talzenna delays prostate cancer progression, apixaban lowers VTE bleeding risk, Lilly’s retatrutide hits Phase III metabolic targets, and FDA warns Novo Nordisk over safety reporting violations [March 2026]
Pfizer’s Talzenna combo significantly delays progression in frontline prostate cancer Topline results from the Phase 3 TALAPRO-3 study indicate that...
Dipeptidyl peptidase-4 inhibitors may be associated with an increased incidence of malignancy
1. Sitagliptin demonstrated the most prominent malignancy-related safety signal among the dipeptidyl peptidase-4 inhibitors studied. Evidence Rating Level: 2 (Good) ...
Finerenone improves albuminuria in adults with type 1 diabetes and chronic kidney disease
1. In this phase 3 trial involving patients with type 1 diabetes and chronic kidney disease, finerenone was associated with...
Early control of systolic blood pressure following intracerebral hemorrhage may improve functional recovery
1. Maintaining systolic blood pressure in a lower, stable range during the first 24 hours after intracerebral hemorrhage was associated...
The Scan by 2 Minute Medicine®: Susie Wiles breast cancer diagnosis drives national screening surge, Jensen Huang’s GTC keynote turns healthcare AI into a pop-culture phenomenon, landmark ACSM guidelines simplify resistance training for longevity, and consumer alert issued for high-pressure cosmetic surgery chains
The Scan by 2 Minute Medicine® is a pop-culture medical newsletter and exclusive benefit for 2 Minute Medicine Plus subscribers....
