#VisualAbstract: Placebo-Controlled Trial of an Oral BTK Inhibitor in Multiple Sclerosis
1. The Bruton’s tyrosine kinase (BTK) inhibitor evobrutinib when compared to placebo treatment in multiple sclerosis patients showed the ability...
Verubecestat linked to worse outcomes among patients with prodromal Alzheimer’s Disease compared to placebo
1. Verubecestat, an orally administered beta amyloid precursor protein-cleaving enzyme 1 (BACE-1) inhibitor , did not slow or prevent the progression...
No decrease in risk of deep vein thrombosis seen with adjunctive pneumatic compression
1. A randomized control trial of adult ICU patients randomized to receive either adjunct intermittent pneumatic compression with pharmacologic thromboprophylaxis...
HCV-positive heart and lung transplant likely safe with post-transplant sofosbuvir-velatasivir treatment
1. HCV-naive patients in need of heart or lung transplants who received organs from HCV-positive donors and were treated with...
Combined anastrozole and fulvestrant therapy found to have improved survival outcomes in metastatic breast cancer
1. A randomized control trial of patients with hormone receptor-positive metastatic breast cancer compared survival outcomes between patients who received...
Shorter treatment regimen found to be noninferior for patients with multidrug resistant tuberculosis
1. A randomized control trial of patients with multidrug resistant tuberculosis found that shorter treatment regimens were noninferior to longer...