Long-term use of apremilast for psoriasis associated with an acceptable safety profile

1. In a prospective observational study of over 1100 patients with moderate to severe plaque psoriasis, long-term use (≥156 weeks) of apremilast was not...

Individualized screening for diabetic retinopathy with fundoscopy and HbA1c

1. Risk of developing clinically significant diabetic retinopathy or macular edema over specified timeframes can be modeled using fundal exam and hemoglobin A1c (HbA1c)...

Risankizumab more effective than ustekinumab for moderate-to-severe psoriasis

1. Risankizumab was associated with a significantly greater improvement in the primary endpoint of ≥90% reduction of the Psoriasis Area and Severity Index (PASI)...

Long term phototherapy can enhance treatment response in vitiligo

1. Examination of prospective studies found that a majority of patients with vitiligo had at least 25% re-pigmentation in response to phototherapy, with rates...

Effective subcutaneous C1-inhibitor for hereditary angioedema prophylaxis: The COMPACT trial

1. The self-administered, subcutaneous C1-inhibitor CSL830 demonstrated a dose-dependent high efficacy in the prophylactic treatment of hereditary angioedema (HAE) attacks compared to placebo. 2. CSL830...

Laser therapy may be effective in patients with infantile hemangiomas

1. In a retrospective review of over 140 infants with infantile hemangiomas (IH), combined neodymium-doped yttrium aluminum garnet laser and pulsed dye laser (Nd:YAG/PDL)...

Patients with psoriasis associated with increased systemic arterial and subcutaneous adipose inflammation

1. In a retrospective cohort study of 12 patients with psoriasis, 8F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) demonstrated significantly increased arterial inflammation...

Hidradenitis suppurativa associated with increased risk of subclinical atherosclerosis

1. In a prospective study of 62 patients with hidradenitis suppurativa (HS) and their matched controls, HS was associated with an increased risk of...

Autosomal dominant, maternal inheritance of infantile hemangioma

1. Pedigrees of families with infantile hemangioma (IH) were consistent with 2 distinct modes of transmission: autosomal dominant transmission and maternal inheritance, both with...

Anti-IL-17A therapy linked to sustained improvement in plaque psoriasis: The UNCOVER trials

1. Patients with moderate-to-severe plaque psoriasis treated with ixekizumab had significantly greater improvements in psoriasis compared to those treated with placebo at the end...
licensing as small

Popular