Ticagrelor monotherapy reduces bleeding risk following percutaneous coronary intervention
1. Clinically relevant bleeding was significantly lower with ticagrelor monotherapy than in the ticagrelor plus aspirin group. 2. Major cardiovascular...
Intravascular ultrasound-guided stent insertion improves outcomes in patients with acute coronary syndrome
1. Target-vessel failure was significantly lower in the ultrasound-guided group than the angiography-guided group. 2. There was no significant difference...
Preventive angioplasty reduces adverse cardiac events in patients with non-flow-limiting vulnerable plaques
1. Patients in the PCI group reported significantly lower rates of cardiac death, revascularization, and hospitalization than those in the...
Positron emission tomography-guided treatment strategy may reduce need for chemotherapy for patients with HER2+ breast cancer
1. 3-year invasive disease-free survival among the PET-based treatment group was 94.8%. 2. There were fewer treatment-related and serious adverse...
Semaglutide improves symptoms and function in obesity-related heart failure
1. Semaglutide showed significant improvements in KCCQ-CSS score and reduction in body weight compared to placebo. 2. There were fewer...
Novel transcatheter heart valve may be effective for management of high-risk aortic regurgitation
1. The 30-day composite primary safety endpoint of > 40.5% was achieved for Trilogy TAVI. 2. 8% of patients who...
Afamitresgene autoleucel as an effective T-cell therapy for synovial sarcoma and liposarcoma
1. Overall response rate to afami-cel in both groups was 37%. 2. The majority of adverse-events were moderate in nature...
Pembrolizumab enhances progression-free survival in patients with locally advanced cervical cancer
1. Progression-free survival at 24 months was higher in the pembrolizumab versus placebo-controlled group. 2. The pembrolizumab-chemoradiotherapy group reported slightly...
Respiratory syncytial virus disproportionately affects pre-term infants over term infants
1. RSV-related ALRI incidence was significantly higher among preterm infants than term infants. 2. This pattern for RSV hospitalizations remained...
High dose aflibercept may be promising for treatment of age-related macular degeneration
1. Aflibercept 8 mg was non-inferior to 2 mg for best-corrected visual acuity at 48 weeks. 2. Ocular adverse events...
