Low troponin threshold could decrease unnecessary cardiac admissions by two-thirds
1. In this prospective cohort study, a low serum troponin concentration under 5ng/L had a negative predictive value of 99.6%...
Novel links identified between genetics, lung function and smoking behavior
1. In this genome-wide genetic association study based on UK Biobank data, novel genome-wide signals of association were found between...
Pre-exposure prophylaxis (PrEP) effective in preventing HIV infection in high-risk gay men
1. In this randomized open-label trial, pre-exposure prophylaxis (PrEP) with once daily tenofovir-emtricitabine was found effective in preventing HIV-1 infection...
Teens identifying with goth subculture at higher risk of depression and self-harm
1. In this longitudinal cohort study, teenagers who identify with goth subculture were found to be at increased risk for...
Increased risk of stroke and coronary heart disease with long work hours
1. In this systemic review and meta-analysis of cohort studies, long work hours was associated with increased risks of stroke...
Meta-analysis confirms protective effect of oral contraceptives against endometrial cancer
1. In this meta-analysis of epidemiological studies, oral contraceptives (OCPs) were shown to have long-lasting protective effects against endometrial cancer....
Aromatase inhibitors superior to tamoxifen in reducing ER positive breast cancer recurrence
1. In this meta-analysis of randomized controlled trials, estrogen receptor (ER) positive breast cancer recurrence rate was lower with an...
Oral cholera vaccine moderately effective in reducing the burden of severely dehydrating diarrhea
1. In this cluster-randomized, open-label trial, a whole-cell cholera vaccine demonstrated moderate effectiveness of around 40% in protecting against severely...
Readmission to the same hospital after major surgery may reduce mortality
1. When readmission was required after major surgery, patients had lower mortality rates if they returned to the same hospital....
Kidney function metrics may help predict risk for cardiovascular disease
1. In this meta-analysis, estimated glomerular filtration rate (eGFR) and albumin-to-creatinine ratio (ACR) were shown to enhance predictive value when...
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