Moderately accelerated cardiac pacing may be beneficial in patients with heart failure with preserved ejection fraction
1. Quality of life at one year was improved in patients with heart failure with preserved ejection fraction (HFpEF) who...
Mavacamten associated with improvement in submaximal exertional tolerance: A secondary analysis of the EXPLORER-HCM randomized trial
1. In the EXPLORER-HCM trial, among 251 included patients, there were significant improvements with mavacamten vs placebo in cardiopulmonary exercise...
Disposable elevator cap duodenoscopes may reduce contamination in endoscopic retrograde cholangiopancreatography – the ICECAP trial
1. Duodenal contamination was detected in 11.2% of patients who underwent endoscopic retrograde cholangiopancreatography (ERCP) using a standard duodenoscope and...
Torsemide not associated with significant difference in all-cause mortality over 12 months compared to furosemide – The TRANSFORM-HF randomized clinical trial
1. In this randomized clinical trial, among 2859 patients, death occurred in 26.1% of patients randomized to torsemide and 26.2%...
Web-based self-treatment may be an effective strategy in the management of benign paroxysmal positional vertigo
1. 85% of individuals randomized to undergo treatment with a web-based self-directed regimen were able to successfully navigate the platform...
Comparison of simulation versus didactic-based instruction for transesophageal echocardiography teaching: the SIMULATOR randomized clinical trial
1. This randomized clinical trial demonstrated significantly increased post-training theoretical and practice scores among cardiology fellows who received simulation-based teaching...
Adding posterior wall isolation to pulmonary vein isolation not beneficial in ablation for patients with persistent atrial fibrillation — the CAPLA trial
1. Among patients with persistent atrial fibrillation (AF) treated with cardiac ablation, those who underwent pulmonary vein (PVI) and posterior...
High-dose selenium not associated with a reduction in morbidity and mortality in high-risk cardiac surgery patients
1. In this randomized clinical trial of 1416 adult cardiac surgery patients, high-dose selenium did not increase the number of...
Frail patients with acute decompensated heart failure may benefit from physical rehabilitation intervention
1. Patients with acute heart failure who were more frail at baseline derived greater benefits from a tailored, multimodal rehabilitation...
Fibrinogen concentrate may be cost-effective for bleeding management in adult cardiac surgery patients
1. In this within-trial economic evaluation of the Fibrinogen Replenishment in Surgery (FIBERS) randomized clinical trial, the median total 7-day...
