High incidence of uveitis in patients with psoriatic disease

  1. Patients with psoriasis and psoriatic disease were more likely to have uveitis and vice versa. Evidence Rating Level: 2 (Good) Study Rundown: Psoriasis is an...

Combination trametinib and dabrafenib show fewer side effects for metastatic melanoma than dabrafenib alone

1. In patients undergoing treatment for metastatic melanoma, there was a statistically significant decreased risk of cutaneous toxic effects in those patients who were...

Promising phase 2 results for new plaque psoriasis therapy

1. Guselkumab, an anti-interleukin-23 antibody, produced better responses in patients with moderate to severe plaque psoriasis than standard anti-TNF alpha therapy.  Evidence Rating Level: 1...

Citrus consumption associated with malignant melanoma

1. In a secondary analysis of two large prospective trials of over 63,000 women and 41,000 men, increased consumption of citrus products, particularly grapefruit,...

US annual incidence of basal cell carcinoma nears 2 million

1. Approximately two million Americans annually have basal cell carcinomas (BCC). The majority of these patients are elderly, male, and Caucasian.  Evidence Rating Level:...

Topical fluorouracil cream reduces the long-term burden of actinic keratoses

1. Treatment with a single treatment of topical fluorouracil cream reduced the long-term number of actinic keratoses (AKs) compared to those who had received...

Incidence of non-melanoma skin cancer continues to increase in the USA

1. The total number of non-melanoma skin cancers (NMSC) in the US population was estimated to have increased to 5,434,193 in 2012 from 4,013,890...

2 Minute Medicine Rewind April 19 – April 26, 2015

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Pembrolizumab versus Ipilimumab in Advanced Melanoma...

Using adhesive strips with dermal sutures does not improve cosmesis

1. When comparing the cosmetic outcome of two different methods of wound closure (interrupted subcuticular sutures alone vs. the combination of overlying adhesive strips...

Medicare beneficiaries have a lower rate of delayed melanoma surgeries

1. The vast majority (>75%) of Medicare beneficiaries studied underwent excision of their melanoma within 1.5 months of their biopsy. 2. Surgical delay of...
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