Quick Take: Long-Term Survival of Patients With Melanoma With Active Brain Metastases Treated With...
Immune checkpoint inhibitors have shown significant antitumor activity in melanoma. However, previous randomized trials have excluded patients with untreated brain metastases due to concerns...
Quick Take: Phase Ib/II Study of Pembrolizumab and Pegylated Interferon Alfa-2b in Advanced Melanoma
Programmed death-1 (PD-1) inhibitors have shown efficacy in the treatment of melanoma. Pre-existing CD8+ T-cell infiltrate and interferon (IFN) gene signature has been shown...
Comparative analysis of wounds from oral mucosa versus skin reveals novel therapeutic targets for...
1. Comparative profiling of wounds induced in the oral mucosa versus skin revealed expression of genes that prime the oral mucosa for wound healing....
Early endovenous ablation of leg ulcers improves healing: The EVRA trial
1. Patients with leg ulcers caused by superficial venous reflux treated with compression therapy experienced earlier time to healing if they were treated with...
Safety confirmation of propranolol use in treatment of infantile hemangiomas
1. In healthy infants, there was no significantly increased risk for cardiovascular or metabolic events associated with propranolol use for treatment of infantile hemangioma. However,...
USPSTF: Behavioral interventions do not reduce sunburn or skin cancer outcomes in adults
1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes in adults.
2. Behavior interventions lead to increased skin...
Early dermatology consultation linked to improved diagnostic accuracy and care in cellulitis
1. Among patients admitted to the hospital for a provisional diagnosis of cellulitis, early dermatologic consultation was associated with improved recognition of pseudo-cellulitis, decreased...
Autologous stem-cell transplantation improves survival in scleroderma patients: The SCOT trial
1. Scleroderma patients treated with myeloablative autologous stem-cell transplantation experienced significantly higher rates of disease-free survival at 52 months post-treatment compared to those treated...
Herpes zoster subunit vaccine may be more cost-effective than live attenuated zoster vaccine
1. The new adjuvanted herpes zoster subunit vaccine was more efficacious and less expensive for all ages at the price of $280 per series...
Despite improving trends in lupus-related mortality, rates appear to remain high relative to non-lupus...
1. Over the 46-year study period, systemic lupus erythematosus (SLE) age-standardized mortality rates (ASMRs) did not decline as much as non-SLE ASMR, and there...
