Roflumilast effective for treatment of chronic plaque psoriasis
1. A significantly greater percentage of both roflumilast groups had clear or nearly clear skin compared to the control group...
Dermatology
Nemolizumab effective in reducing pruritis in atopic dermatitis
1. In this study, nemolizumab with topical agents and oral antihistamines when compared to topical agents and oral antihistamines alone...
Mycophenolate an effective option for morphea treatment
1. In patients with different types of morphea unresponsive to phototherapy and methotrexate, mycophenolate appears to be a safe and...
A Comparison of Psoriasis Severity in Pediatric Patients Treated With Methotrexate vs Biologic Agents
1. Treatment with biologics in pediatric patients with moderate to severe psoriasis was significantly associated with greater reduction in psoriasis...
Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo
1. Immune-related adverse events are associated with a longer recurrence-free survival in patients with stage III melanoma treated with pembrolizumab....
Difelikefalin associated with reductions in itch intensity and improvements in itch-related quality of life
1. In this double-blind phase 3 trial involving patients undergoing hemodialysis who had moderate-to-severe pruritus, a clinically significant decrease in...
Treatment Effect of Omalizumab on Severe Pediatric Atopic Dermatitis: The ADAPT Randomized Clinical Trial
1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to...
The CLASS trial: laser ablation and surgery improve quality-of-life for varicose vein patients compared to sclerotherapy
1. In patients with primary varicose veins followed for 5 years after treatment, those randomized to receive laser ablation or...
Quick Take: 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm
The ideal surgical excision margin for patients with thick (>2 mm) localized cutaneous melanomas is unclear, where the risk of...
Quick Take: Risankizumab compared with adalimumab in patients with moderate-to-severe plaque psoriasis (IMMvent)
In this randomized controlled trial, 605 patients with moderate-to-severe chronic plaque psoriasis were assigned to receive 150 mg risankizumab subcutaneously...
Popular Reports
-
Peripherally inserted central catheters are associated with twice as many complications than midline catheters when used short-term
-
Capecitabine + oxaliplatin chemoradiotherapy does not increase survival, but increases toxicity, compared to capecitabine alone in the postoperative treatment of rectal cancer
-
Ultrasound features associated with shoulder complaints
-
Automated pupillometry may be helpful in opioid agonist therapy dosing for opioid use disorder
-
The Child-Pugh score: Prognosis in chronic liver disease and cirrhosis [Classics Series]
2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.