Duloxetine is effective in refractory chronic cough
1. Duloxetine is significantly more effective than placebo at reducing refractory chronic cough (RCC) frequency and sensitivity. Evidence Rating Level:...
Psychiatry
Reports of high-impact psychiatry studies by medical professionals
Baseline cannabis use may not be associated with abstinence from vaping
1. Among young adults, baseline cannabis use was not associated with nicotine vaping abstinence. 2. 12 weeks of varenicline were...
Middle-aged and older Canadians at high risk of obstructive sleep apnea may have worse mental health outcomes
1. Middle-aged and older Canadian adults at high risk of obstructive sleep apnea (OSA) had worse mental health outcomes than...
Higher dose extended-release buprenorphine may reduce opioid use in patients with heavy fentanyl use
1. In this randomized double-blind controlled trial, both the 100-mg and 300-mg doses of buprenorphine were effective and well-tolerated, with...
Drug-related pressure ulcers may be characterised by medication-related characteristics such as polypharmacy and medication changes rather than baseline immobility
1. Approximately one in nine hospitalised patients with pressure ulcers met criteria for definite drug-related pressure ulcers (DRPU), characterised by...
Sertraline is associated with a lower risk of opioid overdose compared to other selective serotonin reuptake inhibitors in patients taking hydrocodone
1. Sertraline appears to be the safest selective serotonin reuptake inhibitor (SSRI) option for patients taking hydrocodone because it is...
Tai chi may be inferior to cognitive behavioural therapy for the treatment of insomnia after 3 months but not after 12 months
1. Tai chi was inferior to cognitive behavioural therapy (CBT) for treating insomnia after the 3-month intervention, but was non-inferior...
Use of selective serotonin reuptake inhibitors during breastfeeding is not associated with reduced cognitive performance in children
1. In this prospective cohort study, postpartum selective serotonin reuptake inhibitors (SSRIs) use during breastfeeding was not associated with reduced...
CBT, Behavioral Activation, and IPT Reduce Perinatal Depressive Symptoms
1. In this systematic review and meta-analysis, cognitive behavioral therapy (CBT), behavioral activation, and interpersonal therapy (IPT) were more effective...
Exercise may improve physical function and psychological well-being following COVID-19 infection in adults
1. Resistance exercise for three months improved physical function and psychological well-being among adults after COVID-19 infection. Evidence Rating Level:...
