• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Endocrinology

Donor egg cycles more successful than autologous oocytes in cancer survivors

byDenise PongandLeah Hawkins Bressler, MD, MPH
November 22, 2015
in Endocrinology, Obstetrics, Oncology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Women with a history of cancer were less likely to have a successful live birth using autologous oocytes compared to healthy infertile women.

2. In donor oocyte cycles, live birth rates were similar between groups.

Evidence Rating Level: 2 (Good)

Study Rundown: Assisted reproductive technology (ART) is increasingly used to help infertile couples achieve pregnancy. As cancer treatment has improved over the years, more women and men survive to their reproductive years and many turn to ART to achieve a child. Men and women with a history of cancer treatment, including chemotherapy and radiation, may experience impairment or complete loss of reproductive function. Women who received high doses of pelvic radiation are at an increased risk of premature ovarian insufficiency and/or endometrial injury; others are exposed to harmful chemotherapeutic agents. These women may choose to have their own eggs harvested and cryopreserved before undergoing treatment or they may opt to use donor oocytes. Previous work has shown that women who have undergone systemic treatment for cancer have poorer outcomes in regards to oocyte retrieval, embryo transfer, and live birth rates. In the present study, authors found that women with a history of cancer within the last 5 years were less likely to achieve successful live birth using autologous oocytes but equally likely to experience live birth when using donor oocytes.

The strengths of the study were the large quality-controlled population database and adjustment for potential confounders. The study was limited primarily by retrospective design and inclusion of only cancer diagnoses within the last 5 years. Prospective studies are needed to further characterize the success rates of ART among women with a history of cancer.

Click to read the study in Human Reproduction

Relevant Reading: Female cancer survivors are low responders and have reduced success compared with other patients undergoing assisted reproductive technologies

RELATED REPORTS

Infertility linked to higher birth defect risk

High fertilization rates following intracytoplasmic sperm injection (ICSI) [Classics Series]

More live births after natural cycle IVF

In-Depth [retrospective cohort]: This study compared outcomes between 441 women with a history of cancer within the last 5 years and 52,985 women with no history of cancer who utilized assisted reproductive technology. The primary outcomes of interest were conception and live birth rates.

Women with a history of cancer were less likely to conceive and to experience a live birth using autologous oocytes compared to healthy women (p < 0.0001). In donor oocyte cycles, there was no difference in live birth rate between healthy women and those with a cancer diagnosis. Likelihood of live birth varied by type of cancer. Compared to their peers, women with a history of breast cancer were least likely to have a live birth following ART (OR 0.19, CI 0.11-0.30).

Image: CC/Wiki/ScienceGenetics

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: assisted reproductionreproductive endocrinology
Previous Post

The Magpie trial: Magnesium lowers eclampsia risk [Classics Series]

Next Post

High incidence of cognitive impairment associated with colorectal cancer

RelatedReports

Infertility treatments not associated with increased short-term cancer risk
Obstetrics

Infertility linked to higher birth defect risk

April 10, 2016
Adverse pregnancy outcomes associated with thrombophilias [Classics Series]
Obstetrics and Gynecology Classics

High fertilization rates following intracytoplasmic sperm injection (ICSI) [Classics Series]

November 14, 2015
Infertility treatments not associated with increased short-term cancer risk
Obstetrics

More live births after natural cycle IVF

August 30, 2015
Infertility treatments not associated with increased short-term cancer risk
Obstetrics

Infertility treatments not associated with increased short-term cancer risk

August 16, 2015
Next Post
High incidence of cognitive impairment associated with colorectal cancer

High incidence of cognitive impairment associated with colorectal cancer

Stochastic resonance stimulation may decrease apnea of prematurity

Stochastic resonance stimulation may decrease apnea of prematurity

Publication of pneumonia antibiotic guidelines changed prescribing trends

Stimulant medications for ADHD linked to sleep disruption

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • #VisualAbstract: Bimekizumab shows a favourable 2-year safety profile in patients with moderate to severe plaque psoriasis
  • Medical cannabis provides little improvement to sleep in chronic pain patients
  • Alzheimer disease in individuals with Down syndrome has similar variability in age of onset and mortality rate as autosomal dominant forms
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.