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No difference in live birth rates between intracytoplasmic sperm injection and conventional in-vitro fertilization...

...r oocyte retrieved and per oocyte inseminated observed in intracytoplasmic injection group with no impact on outcomes at 12 months post-randomization. Evidence Rating Level: 1 (Excellent) Study Rundown: Intracytoplasmic sperm injection (ICSI) is an IVF technique initially utilized in couples with severe male factor infertility. Recently, ICSI rates have increased relative to rates of conventional IVF despite retrospective studies showing similar o...

[Researcher Comment] Corticosteroid injections for tennis elbow associated with poorer recovery versus placebo

...d physiotherapy to the injection. In our study, we evaluated the effect of combining injection and physiotherapy and found that (a) adding physiotherapy to corticosteroid injection does not solve the problem, (b) the corticosteroid medication appears to be responsible for the recurrence and delayed recovery (as it was much less in the placebo injection), (c) the effect of physiotherapy is compromised when combined with steroid injection, and (d) t...

New molecular probes for melanoma imaging and treatment [PreClinical]

...ur post-injection, with prolonged tumor retention (~12% ID/g) 2 hours post-injection. Co-injection of nonradioactive α-MSH hormone blocked 92% of tumor uptake 1 hour after injection, demonstrating that uptake of the PET probe was MC1R-mediated. Whole-body clearance of the probe was rapid, with 92% of the injected dose cleared by 2 hours post-injection. The kidneys exhibited the highest (non-MC1R-specific) uptake of the probe of all normal organs B...

Patient Basics: Abortion (Termination of Pregnancy)

...uring the first procedure or to repair a perforated uterus. Women rarely become infertile after an uncomplicated abortion. However, infertility may result when surgical abortion leads to endometritis or is complicated by heavy bleeding, perforation or incomplete removal of pregnancy tissue. When To Call a Professional Contact your doctor for any of the following problems: A fever of 100.4 degrees Fahrenheit or higher Bleeding heavier than a normal...

Patient Basics: Soft Tissue Sarcoma

...12074 Phone: 518-882-6729 Toll-Free: 800-522-6676 Fax: 518-882-6730 http://www.acoms.org/ American Urological Association 1000 Corporate Blvd. Linthicum, MD 21090 Phone: 410-689-3700 Toll-Free: 866-746-4282 Fax: 410-689-3800 http://www.urologyhealth.org/ American Urological Association 1000 Corporate Blvd. Linthicum, MD 21090 Phone: 410-689-3700 Toll-Free: 866-746-4282 Fax: 410-689-3800 http://www.urologyhealth.org/ American College of Obstetricia...

Patient Basics: Head Injury In Adults

...706 Phone: 301-459-5900 Toll-Free: 1-800-346-2742 TTY: 301-459-5984 http://www.naric.com/ Brain Injury Association of America 8201 Greensboro Drive Suite 611 McLean, VA 22102 Phone: 703-761-0750 Toll-Free: 1-800-444-6443 Fax: 703-761-0755 http://www.biausa.org/ Brain Trauma Foundation 523 E. 72nd St. New York, NY 10021 Phone: 212-772-0608 Fax: 212-772-0357 http://www.braintrauma.org/ National Institute on Disability and Rehabilitation Research 400...

Patient Basics: Allergy Shots (Allergen Immunotherapy)

...ople receiving allergy shots will be asked to keep to a strict schedule of injections, because missed injections may reduce the benefits and delay the effectiveness of treatment. Risks Most people do not have any bad reactions to allergy shots. Sometimes, you may develop swelling, redness or itching at the site of the injection. These mild reactions typically are treated with antihistamines, and your doctor may decide to adjust the dose for the ne...

High fertilization rates following intracytoplasmic sperm injection (ICSI) [Classics Series]

...suggested improvement in clinical outcomes with ICSI but did not directly compare outcomes with SUZI. In this landmark study, authors investigated ICSI outcomes in a large cohort and directly compared ICSI to SUZI outcomes in 11 sister oocytes. Results demonstrated markedly improved outcomes associated with ICSI (39% clinical pregnancy rate) and, compared with SUZI, ICSI conferred a greater than 18-fold increase in fertilization rate. This landma...

Sperm injection, hatching do not improve live births in IVF for decreased ovarian reserve

...altering eggs and embryos prior to implantation) to maximize success. Two commonly used methods are intracytoplasmic sperm injection (ICSI), where a sperm is directly introduced into the egg, and assisted hatching (AH), where various techniques are used to help the embryo hatch through the zona pellucida and thus aid in implantation. While these techniques improve live birth rate for some, they are not without risk (e.g. AH is associated with an...

Patient Basics: Rotator Cuff Injury

...0 Forbes Boulevard Suite 202 Lanham, MD 20706 Phone: (301) 459-5900 http://www.naric.com/naric/ American Academy of Orthopaedic Surgeons (AAOS) 6300 North River Rd. Rosemont, IL 60018-4262 Phone: (847) 823-7186 Toll-Free: (800) 346-2267 Fax: (847) 823-8125 http://www.aaos.org/ National Athletic Trainers’ Association 2952 Stemmons Freeway Dallas, TX 75247-6196 Phone: (214) 637-6282 Fax: (214) 637-2206 http://www.nata.org/ American Orthopedic Societ...

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