Tag: adjuvant chemotherapy

1. Concomitant pembrolizumab plus chemoradiation therapy was associated with improved antitumor activity and safety profile in patients with previously untreated, locally advanced, stage III non-small cell lung cancer. 2. This treatment regimen represents a promising therapy in patients with previously untreated, locally advanced, stage III non-small cell lung cancer, regardless...
1. Adding celecoxib to adjuvant chemotherapy did not increase disease-free survival or overall survival compared to placebo in patients with stage III colon cancer. 2. Celecoxib treatment led to increased incidence of hypertension and elevated levels of creatinine versus placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Aspirin and cyclooxygenase 2 (COX-2)...
1. Explicit emulation of a target trial investigating the comparative efficacy of a shortened duration of adjuvant chemotherapy in individuals with stage III colon cancer was found to be noninferior to the standard 6-month regimen, consistent with results from the International Duration Evaluation of Adjuvant (IDEA) trial. 2. In contrast,...
1. In a prospective cohort study of over 3000 patients with breast cancer, more than 50% of patients discontinued their adjuvant hormone therapy by 5 years. 2. Risk factors for discontinuation of adjuvant hormone therapy in patients with breast cancer include family history of ovarian cancer, extremes in age, higher...