Tag: alanine aminotransferase (ALT)

Alpha-1 antitrypsin (AAT) is a major protease inhibitor responsible for the inhibition of neutrophil elastase and proteinase 3. Alpha-1 antitrypsin deficiency (AATD) is a genetic disease that can lead to accelerated destruction of lung parenchyma and accumulation of AAT in hepatocytes. Severe AATD is caused mainly by the homozygous...