Tag: aspirin

1. In this randomized controlled trial, single dose aspirin given two days prior to fecal immunochemical testing (FIT) did not increase test sensitivity for detection of colorectal cancer at 2 predefined cutoffs. 2. Study findings contrast with previous observational studies that showed increased sensitivity of FIT in users of low-dose...
1. In this post-hoc analysis of data from the NAVIGATE-ESUS trial, which evaluated strategies to prevent recurrent stroke in patient of embolic stroke of undetermined source, use of rivaroxaban was linked with a lower risk of recurrent stroke compared to aspirin in patients with moderate to severe left atrial...
1. In this retrospective cohort study conducted in Michigan, aspirin therapy combined with warfarin for patients without a clinical indication was associated with increased rates of major bleeding, emergency visits for bleeding, and hospital admissions for bleeding. 2. Among these patients, there was no difference in rates of thrombosis or...
1. This study evaluated the effects of post-diagnosis low-dose aspirin on prostate cancer-specific mortality and found no overall benefit. 2. The study did find a modest benefit in patients taking aspirin for at least 5 years after diagnosis. Evidence Rating Level: 2 (Good) Study Rundown: Several recent papers have suggested that regular,...
1. A model was constructed to predict bleeding risk in patients taking aspirin to prevent cardiovascular disease. 2. The predicted data closely match the observed data, supporting the use of this model in future studies and potentially in clinical decision making. Evidence Rating Level: 2 (Good) Study Rundown: In 2016, the U.S....
1. In this systematic review and meta-analysis, while aspirin use among patients without cardiovascular disease was associated with fewer adverse cardiovascular events, it was not associated with a reduction in all-cause mortality. 2. The use of aspirin in patients without cardiovascular disease was associated with increased risk of major bleeding. Evidence Rating...
Association between antithrombotic medication use after bioprosthetic aortic valve replacement and outcomes in the Veterans Health Administration system Patients that have undergone bioprosthetic aortic valve replacement (bAVR) are at an increased risk of thromboembolism. Recommendations and strategies surrounding the use of antithrombotic medications, however, vary. In this retrospective cohort study,...
1. Aspirin combined with warfarin was linked with increased bleeding but not less thromboembolism compared with aspirin alone after bioprosthetic aortic valve replacement. 2. Dual antiplatelet therapy showed a non-significant trend towards increased bleeding but no less thromboembolism compared with aspirin alone after bioprosthetic aortic valve replacement. Evidence Rating Level: 2...
1. Patients initially treated with rivaroxaban following total knee or hip arthroplasty experienced similar rates of venous thromboembolism (VTE) regardless of continued rivaroxaban use or switching to aspirin for extended VTE prophylaxis. 2. No significant difference in rates of major bleeding complications was observed between aspirin and rivaroxaban treated groups. Evidence...
1. Low-dose aspirin significantly reduced the incidence of preterm preeclampsia in women identified as high-risk for preeclampsia using a screening protocol that combined maternal factors with biochemical measurements at 11-13 weeks of gestation. 2. No significant differences in adverse outcomes were found in women given low-dose aspirin compared to placebo. Evidence...