Tag: FEV

1. In this multicenter, phase 3 study of cystic fibrosis patients who were previously unresponsive to modulator regimens, triple-combination therapy with the next-generation corrector elexacaftor resulted in a significantly improved percentage of predicted forced expiratory volume in one second versus placebo after 4 and 24 weeks. 2. Improvements were also...
1. In this retrospective cohort study, an FEV1:FVC threshold of 0.71 was the best fit for discriminating COPD-related events, though it was not statistically different than using 0.70. 2. The FEV1:FVC 0.70 threshold provided optimal discrimination in a subgroup analysis of ever smokers and in adjusted models. Evidence Rating Level: 2...