Tag: heart failure

1. Receiving medications from a greater number of drug classes is linked to lower incidence of rehospitalization and death, for patients in heart failure with reduced ejection fraction (HFrEF). 2. Approximately half of HFrEF patients are not receiving medical therapies that follow clinical guidelines established by the American College of...

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1. Patients experienced a greater incidence of severe adverse events during the 3-month period following prescription of a steroid burst compared to the 3-month period prior. 2. During the posttreatment period, the risk for severe adverse events generally appeared to decrease over time but nonetheless remained elevated above baseline. Evidence Rating...

1. The reduction in Brain Natriuretic Peptide, in conjunction with worsening renal failure, can predict prognosis of patients with acute heart failure Evidence Rating: 2 (Good) For patients with acute heart failure (AHF), congestion is one of the primary reasons for hospital admission. A common decongestive treatment employs intravenous loop diuretics:...

Physical exercise associated with reduced risk of chronic pain in university students 1. Higher frequency, intensity, and duration of physical exercise linked to lower risk of chronic pain in Norwegian University students Evidence Rating: 3 (Average) Chronic pain is estimated to impact around one-third of the population, and is a leading cause...

The association between use of proton-pump inhibitors and excess mortality after kidney transplantation: A cohort study 1. PPI use may be associated with an increased mortality risk in patients who have received kidney transplants. Evidence Rating Level: 1 (Excellent) Proton-pump inhibitors (PPIs) are commonly prescribed to kidney transplant recipients (KTRs) to protect...

1. Heart failure patients whose EF deteriorated from ≥50% to between 40% and 50% were at an increased risk of mortality and cardiovascular events Evidence Level Rating: 2 (Good) Clinicians use left ventricular ejection fraction (LVEF) to guide treatment of heart failure (HF). Patients with HF are commonly divided into two...

1. Exposure to higher levels of air pollutants was associated with increased dementia incidence, with the 5 years preceding onset being the most impactful. 2. The association between dementia and air pollutant exposure was amplified in patients with cardiovascular disease, specifically heart failure and ischemic heart disease. Evidence Rating: 2 (Good) With increasing...

Association of a Care Bundle for Early Sepsis Management With Mortality Among Patients With Hospital-Onset or Community-Onset Sepsis 1. Sepsis bundles were not significantly associated with decreased risk of mortality or reduced vasopressor treatment time in community- or hospital-onset sepsis. 2. Components of the SEP-1 bundle, such as broad-spectrum IV antibiotic...