1. In a randomized control trial, caffeine administration was associated with greater cardiovascular effects in post-pubertal boys than girls.
2. Among postpubertal females, there was a significant interaction between the menstrual cycle phase and the effect of caffeine on heart rate and blood pressure.
Evidence Rating Level: 2 (Good) ...
1. Patients in septic shock who received esmolol achieved reductions in heart rate to target levels without an associated increase in adverse events.
2. The 28-day mortality rate was 49.4% among patients receiving esmolol compared to 80.5% among patients receiving standard care (p<.001).
Evidence Rating Level: 1 (Excellent)
Study Rundown: Septic...