Tag: metastatic thyroid cancer

1. Multifocal papillary thyroid carcinoma (PTC) was associated with a higher risk of cancer recurrence than unifocal PTC. 2. Large (>1cm) and small (≤1 cm), adult and pediatric PTC, and high (≥3), but not low (2), foci count were associated with an increased risk of multifocal PTC recurrence. Evidence Rating Level:...
1. A metastatic anaplastic thyroid cancer with inactivation of tumor suppressor gene TSC2 and overactivation of the mammalian target of rapamycin (mTOR) pathway proved exquisitely sensitive to everolimus, an inhibitor of mTOR, providing 18 months of treatment response before development of acquired tumor resistance. 2. The resistant tumor harbored a...
Feb 13th – Published today, 8 out of 20 patients with metastatic thyroid cancer refractory to radioiodine therapy trapped therapeutic doses of radioiodine after administration of Selumetinib. Image: PD 1. 8 out of 20 patients with metastatic thyroid cancer refractory to radioiodine therapy trapped therapeutic doses of radioiodine after administration of Selumetinib. 2. 7...