Tag: neural tube defect

1. Folic acid supplementation prevents neural tube deficits during pregnancy, but if continued beyond the recommended first trimester, may positively impact neurodevelopment and cognitive performance in children at seven years of age. Evidence Rating Level: 2 (Good) Periconceptional folic acid (FA) supplementation is a protective factor against neural tube defects (NTD), with...
1. Folic acid supplementation prevents neural tube deficits during pregnancy, but if continued beyond the recommended first trimester, may positively impact neurodevelopment and cognitive performance in children at seven years of age. Evidence Rating Level: 2 (Good) Periconceptional folic acid (FA) supplementation is a protective factor against neural tube defects (NTD),...
Odanacatib for the Treatment of Postmenopausal Osteoporosis: Results of the LOFT Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial and LOFT Extension Study 1. The cathepsin K inhibitor odanacatib reduced the risk of fracture but was associated with significantly increased risk of cardiovascular events, specifically stroke, in postmenopausal women with osteoporosis compared to...