Tag: POISE trial

Classics Series, Landmark Trials in Medicine

POISE Trial: Perioperative Metoprolol Reduces MI but Increases Stroke & Mortality [Classics Series]

byAndrew Cheung, MD MBAand1 others

August 13, 2025

1. In adults undergoing noncardiac surgery, perioperative β-blocker therapy with extended-release metoprolol significantly reduced nonfatal myocardial infarction (MI) risk but ...

Perioperative Aspirin may increase major bleeding in noncardiac surgery (POISE 2)

byDavid Mattos, MDand1 others

April 21, 2014

Image: CC/Wiki 1. Perioperative Aspirin use did not correlate with reduction of death or nonfatal myocardial infarction within 30 days ...

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